Vaccinal prevention of nodular dermatitis in Hereford cattle (clinical and immunological implications)

Animal vaccination is the principal method of preventing nodular dermatitis in cattle. Objective: to analyze the impact of using a specific transfer factor in vaccination of Hereford cattle against nodular dermatitis on the development of immunity and indices of animal homeostasis. Application of the transfer factor and the vitamin preparation Asidivit in the vaccination of animals against nodular dermatitis has reduced the reactogenicity of the vaccine in the form of a lower temperature reaction to the medicinal preparation of biological origin. The combined application of the immunoamplifier and Asidivit decreased the negative impact of vaccination on the liver of animals. The greatest quantitative decrease in bilirubin in the blood serum by 14% was observed. It made it possible to achieve a significant increase in antibodies in the blood serum by 72.4% compared to the initial analysis and an increase in the number of antibody-positive animals up to 80%