Anomalous cyclotron mass dependence on the magnetic field and Berry’s phase in (Cd₁-x-γZnxMnγ)₃As₂ solid solutions

Shubnikov-de Haas (SdH) effect and magnetoresistance measurements of single crystals of diluted II-V magnetic semiconductors (Cd₁-x-γZnxMnγ)₃As₂ (x+γ= 0.4, y=0.04 and 0.08) are investigated in the temperature range T=4.2 ÷ 300 K and in transverse magnetic field B=0 ÷ 25

STUDY THE POSSIBILITY OF MODELING OF THE CUTTING PROCESS IN THE CHAMBER FOR CRUSHING FRUIT AND VEGETABLES

The grinding process of fruits and vegetables in the preparation of juice with pulp, usually carried out by means juicers, blenders or grinders with a relatively slowly rotating blades and stationary gratings with a continuous flow of raw materials. Intensification of processes of division of the products of the conversion will asunder allow sharply duration and raise the uniformity of the processing cheese that will say on quality ready drink as a whole. The interaction of the blade and material is characterized effort of the cutting moreover the general power, acting on blade on the part of material, is not found in planes of the cutting in consequence of which on blade of the knife, alongside with vertical, acts and horizontal forming power. Horizontal form to deform (change) sidebar cut-ting edge of the knife in consequence of which in general event provision to necessary acerbity in flat material requires increase of his(its) thickness and using the additional relationships (the jumper). It is installed that values of magnitude of deformation and speed of its extending are connected among themselves through the parameters characterizing pressure and plasticity of medium of installation of machining. Hence, speed depends on properties of a body in which the pulse is passed round. In the majority of materials speed of extending of a pulse appears an order of 5 103 km/s. Accounting of received data in the determination of rational cutting speeds for different materials with elastoplastic properties (approximation cutting speed for the propagation velocity of deformation) will allow to reduce pre-separation deformation and, respectively, spent on her work, localization stress under cutting edge, and, as consequence will lead to higher product yield and improve the purity of the slices. Improving the quality cutting may be associated with an increase of inertia of the structural elements of the material (fibers) by increasing the speed of the process

Assessment of Nutritive Status in Patients with Symptoms of Heart Failure

Aim of the research. To study the parameters of nutritional status of patients with acute and chronic coronary syndromes and symptoms of heart failure in conjunction with clinical, anthropometric, laboratory parameters, structural and functional characteristics of the heart. Materials and methods. A cross-sectional study of 106 patients with acute and chronic coronary syndromes and symptoms of heart failure. All subjects underwent an integrated assessment of the nutritional status (anthropometric, caliperometric (caliper metric) indicators, CONUT scale (lymphocytes, total cholesterol, albumin), hormonal indicators (N-terminal brain natriuretic propeptide), structural changes in the myocardium using echocardiography, exercise tolerance by 6-minute walk test. Results. Nutritional deficiency, according to CONUT scale, was found in 81.1 % of cases (86 patients). In the group of patients with the presence of malnutrition, there were significantly high level of fibrinogen and N-terminal brain natriuretic propeptide. The interpretation of changes in body composition showed a significant upward trend in the prognostic index of hypotrophy and a decrease in lean body mass as heart failure progresses. The dependence of nutritive insufficiency on the CONUT scale with laboratory parameters (creatinine, fibrinogen, brain natriuretic propeptide), structural and functional characteristics of the heart (diastolic and systolic dimensions of the left ventricle, ejection fraction, left ventricular myocardial mass index), a functional indicator of tolerance to the physical load (6-minute walk test) was determined. Conclusion. An integrated analysis of nutritional status indicators of patients with heart failure revealed an increase of malnutrition signs with an increase of the severity of HF. Pathological effects of nutritional deficiency are associated with impaired left ventricular systolic function, reduced exercise tolerance

Room Temperature High-Field Spin Dynamics of NV Defects in Sintered Diamonds

Sintered oriented nanodiamond arrays with the extremely high concentrations of the nitrogen-vacancy (NV) centers (up to 103 ppm) were investigated by the W-band (94 GHz) electron spin echo electron paramagnetic resonance techniques. The NV centers were fabricated by the high-pressure high-temperature sintering of detonation nanodiamonds (DND) without the post or prior irradiation of the samples. The processes of polarization and recovery of the equilibrium population of the spin sublevels by optical and microwave pulses have been examined at room temperature in high magnetic fields corresponding to the fine-structure transitions for the NV defects at 94 GHz (3,250-3,450 mT). A long spin coherence time of 1.6 μs and spin-lattice relaxation time of 1.7 ms were measured. The results were compared with those obtained on the NV centers fabricated by the irradiation and subsequent annealing of the commercially available bulk diamonds. It was shown that the relaxation characteristics of the NV defects were similar in the both types of the samples despite the extremely high concentrations of NV defects and isolated nitrogen donors in the sintered DND. © 2013 Springer-Verlag Wien

Efficacy of Angio-Seal Device for Primary And Complicated Haemostasis: a Multicentre Retrospective Assay

Background. Femoral approach in endovascular surgery remains relevant being, however, associated with the risk of fatal and non­fatal complications. Modern techniques for instrumental haemostasis achieved with the Angio­Seal device (Terumo Corporation, Japan) provide an opportunity to reduce the number of fatal and non­fatal complications. Aim. A multicentre assay of the efficacy and safety of instrumental puncture closure using Angio­Seal devices (Terumo Corporation, Japan) in various settings and clinical situations.Materials and methods. A multicentre retrospective analysis of 1088 use cases of the Angio­Seal device  (Terumo Corporation, Japan) for “primary” and “complicated” instrumental haemostasis after femoral access  has been conducted for the years 2018–2020. The mean patient age was 62.3 ± 11.6 years, including 845 men (78.0%) and 243 women (22.0%). Five centres for routine and emergency endovascular radiology participated in the study.Results. The Angio­Seal device (Terumo Corporation, Japan) demonstrated a high method efficiency, with a  97.0% success rate of “primary” instrumental haemostasis (1055 of 1088 total successful haemostatic  procedures) in various clinical settings. Arterial thrombosis at the approach side had a 3.0% complication rate  (5 of 33 observations), all other complication types associated with haemorrhagic events (8 cases) or device malfunction and damage (20 cases).Discussion. The assay conducted suggests that the incidence of “complicated” instrumental haemostasis  relates to technical drawbacks of the device application that required advance planning. The key identified  prerequisites for a successful Angio­Seal application (Terumo Corporation, Japan) are the alignment of anchor tube­delivery through soft tissue into the vessel lumen and its positioning inside the vessel.Conclusion. The constructive features and instrumental haemostatic technique realised in the Angio­Seal  device (Terumo Corporation, Japan) enable an effective and safe primary sealing of arterial puncture site in 97% cases

Defects in Nanodiamonds: Application of High-Frequency cw and Pulse EPR, ODMR

© 2014, Springer-Verlag Wien. Different aspects of applications of electron paramagnetic resonance (EPR) based techniques including high frequency (HF) electron spin echo (ESE), electron-nuclear double resonance (ENDOR) and optically detected magnetic resonance (ODMR) approaches to study diamond nanostructures are examined

ЭФФЕКТИВНОСТЬ РЕТРОПЕРФУЗИОННОЙ ПОДДЕРЖКИ КОРОНАРНОГО КРОВОТОКА В ПРОЦЕССЕ ЭНДОВАСКУЛЯРНОЙ КОРРЕКЦИИ СЛОЖНЫХ ФОРМ ПОРАЖЕНИЙ ПЕРЕДНЕГО КОРОНАРНОГО БАССЕЙНА У ПАЦИЕНТОВ С ОСТРЫМ КОРОНАРНЫМ СИНДРОМОМ С ПОДЪЕМОМ СЕГМЕНТА ST

The most adverse outcomes of PCI in patients with ACS-STE occurs during prolonged endovascular correction of complex coronary impairment forms in the absence of coronary arterial flow support. The aim of this study was to assess the effectiveness of retroperfusion support of coronary blood flow during endovascular correction of complex anterior coronary bed impairment forms in patients with ACS-STE. The results of treatment of 12 patients who underwent endovascular image-guided intervention was analyzed from 26.04.2012 to 10.05.2014. 1st group consisted of 6 (50%) patients who underwent retroperfusion support of coronary circulation. 2nd group consisted of 6 (50%) patients in whom retroperfusion support have not been performed. In 1st group there there was a significant decrease in ST-segment elevation during retroperfusion after 60 seconds of the absence of antegrade blood flow in the anterior coronary bed compared with patients who underwent angioplasty without the coronary blood flow support (ST in V1-V3 with retroperfusion was 2,2±0,4 mm; ST in V1-V3 without retroperfusion was 2,9±0,4 mm; p=0,027). In 2nd group, in the absence of retroperfusion support in all patients after 60 seconds of antegrade flow overlap there was a significant increase in segment elevation ST (ST in V1-V3 was 2,7±0,3 mm; p = 0,027) compared to the initial ECG pattern. Similar dynamics was observed in blood pressure levels. Thus, selective retroperfusion of great cardiac vein can be used as an intraoperative support of cardiac hemodynamics in patients with ASC-STE.Наибольшее количество неблагоприятных исходов ЧКВ у больных с OKCotST возникает в процессе длительной эндоваскулярной коррекции сложных форм поражений переднего коронарного бассейна в отсутствие поддержки венечного артериального кровотока. Целью данного исследования являлось проведение оценки эффективности ретроперфузионной поддержки коронарного кровотока в процессе эндоваскулярной коррекции сложных форм поражений переднего коронарного бассейна у пациентов с OKCotST. В период с 26.04.2012 г. по 10.05.2014 г. проанализированы результаты лечения 12 пациентов, перенесших рентгеноэндоваскулярное вмешательство. 1-ю группу составили 6 (50%) больных, которым выполнялась ретроперфузионная поддержка коронарного кровоснабжения, 2-ю группу - 6 (50%) пациентов, которым ретроперфузионная поддержка не выполнялась. В 1-й группе в процессе ретроперфузии на 60-й секунде отсутствия антеградного кровотока по переднему коронарному бассейну наблюдалось достоверное уменьшение элевации сегмента ST по сравнению с ангиопластикой без поддержки коронарного кровотока (STв V1-V3 при ретроперфузии - 2,2±0,4 мм; ST в V1-V3 без ретроперфузии - 2,9±0,4 мм; p=0,027). Во 2-й группе, при отсутствии ретроперфузионной поддержки у всех пациентов на 60-й секунде перекрытия антеградного кровотока наблюдалось достоверное увеличение элевации сегмента ST (ST в V1-V3 - 2,7±0,3 мм; p=0,027) по сравнению с исходной ЭКГ-картиной. Подобная динамика прослеживалась и в отношении показателей артериального давления. Таким образом, селективная ретроперфузия большой кардиальной вены может быть использована как способ интраопе-рационной поддержки кардиогемодинамики у пациентов с OKCotST

Endonasal infrared thermometry for the diagnosis of allergic inflammation of the nasal mucosa in patients with bronchial asthma

© 2017, Nizhny Novgorod State Medical Academy. All rights reserved. Bronchial asthma (BA) is often associated with chronic inflammatory processes in the nasal mucosa; these processes give rise to allergic rhinitis, chronic rhinosinusitis, adenoiditis, and polypous rhinosinusitis. Due to their multiple symptoms, these diseases of the upper respiratory tract, especially allergic rhinitis, are often difficult to verify in patients with asthma. The aim of the study was to evaluate the diagnostic potential of endonasal IR thermometry in BA patients suspected of allergic rhinitis. Materials and Methods. Fifty children diagnosed with both BA and allergic rhinitis and 15 healthy children, matched by gender and age, participated in the study. The endonasal temperature determined with contactless IR thermometry was confronted with the symptoms of allergic rhinitis and sinusitis assessed with the TNSS and SNOT-20 questionnaires. The results were compared with the severity of nasal obstruction as determined through the anterior active rhinomanometry. Results. The nasal temperature in patients with asthma and allergic rhinitis was 33.77 [33.37; 34.17]°С, which was significantly lower than that in the group of healthy children (34.98 [34.57; 35.39] °С; p=0.0006); the body temperature did not differ between the groups (36.55 [36.45; 36.65] and 36.58 [36.40; 36.76] °С, respectively; p=0.5). We found a negative correlation between the values of nasal temperature and the sinusitis symptom scores in patients with BA and allergic rhinitis (R=–0.32; p=0.02). Conclusion. Patients with both BA and allergic rhinitis showed a decreased endonasal temperature in comparison with healthy children; the endonasal temperature can serve an indicator of allergic inflammation of the nasal mucosa

Феномен формирования мезенхимальных островков из клеток костного мозга мышей в системе in vitro

An attempt to check experimentally the possibility of structure functional units existence in mesenchymal cells, similar to hemopoetic and erythroblastic islets, has been made. Experiments on long (in vitro) cultivation of adhesive rat marrow elements have been made.It has been found that from the 6 day of observation there were specific cell formations with islet-like structure in the culture. An epitelioid cell surrounded by round elements was situated in the center. Up to 12-14 days the number of mesenchymal islets reached its maximum (up to 46,0 ⋅ 106 cells), after that it decreased gradually and up to 24 days it almost disappeared. The islets were a part of mesenchymal colonies.The authors suppose that these formations are structure functional units of mesenchymopoiesis where proliferation and differentiation processes of mesenchymal stem cells and their closest scions proceed.В работе предпринята попытка экспериментально проверить возможность существования у мезенхимальных клеток костного мозга структурно-функциональных единиц, подобных гемопоэтическим и эритробластическим островкам. Проведены опыты по длительному (in vitro) культивированию адгезирующих элементов костного мозга мышей.Установлено, что начиная с 6-х сут наблюдений в культуре формируются специфические клеточные образования, имеющие островковоподобную структуру. В центре располагается эпителиоидная клетка, окруженная округлыми элементами. К 12—14-м сут количество мезенхимальных островков достигает максимума (до 46,0 ⋅ 106 клеток), после чего постепенно снижается, и они практически исчезают к 24-м сут. Островки входят в состав мезенхимных колоний.Авторами высказано предположение, что данные образования представляют собой структурно-функциональную единицу мезенхимопоэза, в которой протекают процессы пролиферации и дифференцировки мезенхимальных стволовых клеток и их ближайших потомков