4 research outputs found
Linear-T scattering and pairing from antiferromagnetic fluctuations in the (TMTSF)_2X organic superconductors
An exhaustive investigation of metallic electronic transport and
superconductivity of organic superconductors (TMTSF)_2PF_6 and (TMTSF)_2ClO_4
in the Pressure-Temperature phase diagram between T=0 and 20 K and a
theoretical description based on the weak coupling renormalization group method
are reported. The analysis of the data reveals a high temperature domain
(T\approx 20 K) in which a regular T^2 electron-electron Umklapp scattering
obeys a Kadowaki-Woods law and a low temperature regime (T< 8 K) where the
resistivity is dominated by a linear-in temperature component. In both
compounds a correlated behavior exists between the linear transport and the
extra nuclear spin-lattice relaxation due to antiferromagnetic fluctuations. In
addition, a tight connection is clearly established between linear transport
and T_c. We propose a theoretical description of the anomalous resistivity
based on a weak coupling renormalization group determination of
electron-electron scattering rate. A linear resistivity is found and its origin
lies in antiferromagnetic correlations sustained by Cooper pairing via
constructive interference. The decay of the linear resistivity term under
pressure is correlated with the strength of antiferromagnetic spin correlations
and T_c, along with an unusual build-up of the Fermi liquid scattering. The
results capture the key features of the low temperature electrical transport in
the Bechgaard salts
Decontamination strategies and bloodstream infections with antibiotic-resistant microorganisms in ventilated patients : a randomized clinical trial
Importance: The effects of chlorhexidine (CHX) mouthwash, selective oropharyngeal decontamination (SOD), and selective digestive tract decontamination (SDD) on patient outcomes in ICUs with moderate to high levels of antibiotic resistance are unknown. Objective: To determine associations between CHX 2%, SOD, and SDD and the occurrence of ICU-acquired bloodstream infections with multidrug-resistant gram-negative bacteria (MDRGNB) and 28-day mortality in ICUs with moderate to high levels of antibiotic resistance. Design, setting, and participants: Randomized trial conducted from December 1, 2013, to May 31, 2017, in 13 European ICUs where at least 5% of bloodstream infections are caused by extended-spectrum [beta]-lactamase-producing Enterobacteriaceae. Patients with anticipated mechanical ventilation of more than 24 hours were eligible. The final date of follow-up was September 20, 2017. Interventions: Standard care was daily CHX 2% body washings and a hand hygiene improvement program. Following a baseline period from 6 to 14 months, each ICU was assigned in random order to 3 separate 6-month intervention periods with either CHX 2% mouthwash, SOD (mouthpaste with colistin, tobramycin, and nystatin), or SDD (the same mouthpaste and gastrointestinal suspension with the same antibiotics), all applied 4 times daily. Main outcomes and measures: The occurrence of ICU-acquired bloodstream infection with MDRGNB (primary outcome) and 28-day mortality (secondary outcome) during each intervention period compared with the baseline period. Results: A total of 8665 patients (median age, 64.1 years5561 men [64.2%]) were included in the study (2251, 2108, 2224, and 2082 in the baseline, CHX, SOD, and SDD periods, respectively). ICU-acquired bloodstream infection with MDRGNB occurred among 144 patients (154 episodes) in 2.1%, 1.8%, 1.5%, and 1.2% of included patients during the baseline, CHX, SOD, and SDD periods, respectively. Absolute risk reductions were 0.3% (95% CI, -0.6% to 1.1%), 0.6% (95% CI, -0.2% to 1.4%), and 0.8% (95% CI, 0.1% to 1.6%) for CHX, SOD, and SDD, respectively, compared with baseline. Adjusted hazard ratios were 1.13 (95% CI, 0.68-1.88), 0.89 (95% CI, 0.55-1.45), and 0.70 (95% CI, 0.43-1.14) during the CHX, SOD, and SDD periods, respectively, vs baseline. Crude mortality risks on day 28 were 31.9%, 32.9%, 32.4%, and 34.1% during the baseline, CHX, SOD, and SDD periods, respectively. Adjusted odds ratios for 28-day mortality were 1.07 (95% CI, 0.86-1.32), 1.05 (95% CI, 0.85-1.29), and 1.03 (95% CI, 0.80-1.32) for CHX, SOD, and SDD, respectively, vs baseline. Conclusions and relevance: Among patients receiving mechanical ventilation in ICUs with moderate to high antibiotic resistance prevalence, use of CHX mouthwash, SOD, or SDD was not associated with reductions in ICU-acquired bloodstream infections caused by MDRGNB compared with standard care