State regulation features of university integration into national innovative system in the light of "triple helix" modern concept

The study is devoted to state regulation features research of university integration of into national innovative system in the light of “triple helix” modern concept developed by it’s kovit’s leidesdorf describing development of innovative systems through dynamics of state, business and universitiesyesBelgorod State Universit

ASSESSMENT OF EMOTIONAL INTELLIGENCE LEVEL IN INTERCULTURAL EDUCATIONAL ENVIRONMENT

Introduction. Currently, the training of professionally competent specialists is a priority in the higher education system. One of the productive creative approaches is the development of emotional intelligence (EI/EQ), which contributes to the development of emotional intercultural competence to accelerate adaptation in a new intercultural environment. Aim. The aim of the research is to empirically determine the level of emotional intelligence in the intercultural context for further improving work with students of the humanities and economics specialities and proposing new techniques that develop emotional intercultural competence. Methodology and research methods. The methodological basis of the research is the concept of developing emotional intelligence as an integral part of soft skills. To study the level of emotional intelligence, the authors used the Mark Daniel Self-Scoring Emotional Intelligence Tests, which are a compilation of tests designed to study the level of emotional intelligence and determine the strengths and weaknesses of the test takers. The methods of psycho-diagnostics, comparison and generalisation of the obtained results were used. The test results were analysed using the SPSS.27 statistical package. Results. The research results help to understand the psychological characteristics of students of the humanities and economics specialities, taking into account the cultural context, which makes it possible to predict the difficulties and problems faced by teachers in the process of work with this type of students, to more accurately determine the characteristics and motives of their behaviour and the characteristics of the professional development of the individual. It also helps to select the right curriculum to meet students' needs. Scientific novelty. The scientific novelty of the research consists in supplementing the existing knowledge in the field of EI about the psychological characteristics of representatives of the humanities and economics specialities in the context of intercultural communication and further forecasting their development based on correctly selected teaching methods. Practical significance. The presented features of students of the humanities and economics specialities can be employed by teachers when interacting with them and organising the educational process, taking into account their interests and needs, as well as adjusting the level of development of EI. The results obtained can be useful in the preparation of educational and methodological complexes specifically designed for the development of emotional intercultural competence. © 2022 Authors. All rights reserved

Disorders in the System of Mineral and Bone Metabolism Regulators—FGF-23, Klotho and Sclerostin—in Chronic Kidney Disease: Clinical Significance and Possibilities for Correction

The chapter discusses the current understanding of the system of mineral and bone metabolism regulators—FGF-23, Klotho and sclerostin—disturbances in chronic kidney disease (CKD). In the chapter we presented the date, including our own results, which allow to suggest the change in the ratio of FGF-23-Klotho-sclerostin in CKD as an early biomarker not only for the chronic kidney damage but also for high cardiovascular (CV) risk. Results of studies show that disorders in FGF-23-Klotho-sclerostin ratio correlate with the frequency and severity of hypertension, vascular calcification, cardiac remodelling, anaemia, malnutrition, inflammation and strong aggravate CV risk in CKD. It was found independent from blood pressure (BP) action of increased serum FGF-23 on the myocardium as well as the correlation of serum high-sensitive troponin I with increased serum FGF-23 and low Klotho levels in CKD patients. At the same time, it was shown that renoprotective therapy, including renin-angiotensin blockers, low-protein diet with amino/keto acid supplementation and phosphate binders, erythropoiesis stimulators, vitamin D metabolites used to get the target levels of BP, serum phosphorus, haemoglobin, parathyroid hormone and nutritional status disorders correction can reduce the risk of CV events, as the major cause of death in CKD patients

Nutritional Status Disorders in Chronic Kidney Disease: Practical Aspects (Systematic Review)

Despite the significant achievements in the management of chronic kidney disease (CKD) patients, the mortality rate of these patients still remains high. Nutritional status disorders (NSD) are considered now as one of the prognostic risk factors not only for dialysis but also for predialysis CKD stages. Since the publication of KDIGO 2012 guidelines for CKD patient’s management, there has been some significant advancement in our understanding of main NSD mechanisms in CKD, including different nosological group patients (first, in diabetic and systemic diseases patients). At the same time, there is still an urgent need for randomized trials for better-informed decisions and future optimization of CKD patients’ care. This chapter provides the current data on all aspects of NSD in CKD: etiology, diagnosis, prevention, and treatment approaches, as well as on risk factors of NSD at predialysis stages and in chronic hemodialysis patients. Considerable attention was devoted to the diagnosis and differential diagnosis of NSD in CKD patients. It was determined that the overall strategy for dietary treatment contributed to improving the life quality of patients and slowing down of CKD progression. The review is written based on the published results of clinical studies performed on the position of evidence-based medicine

The Study of Economic Activity of Russian Corporations in Modern Economy

The article discusses the results of the conducted in Russia's economic reforms, the terms “company”, “corporate governance” of their use in the media and in literature, as well as the formation of the idea of the control system adopted by the Corporation, as one of the ways of good governance and the withdrawal of Russian companies out of the crisis. The most urgent tasks in the practical management of corporate property can now be considered: clarifying the structure and composition of corporate ownership, the formalization of the goals, objectives and principles of its functioning, the definition of criteria for management efficiency, which, in turn, require search and study methodological approaches to solving specific economic tasks - evaluation of individual objects of corporate ownership and to determine effective areas of structural development. According to the authors, only the use of complex techniques from different sections of the economy can give the desired economic effect and solve the pressing problem of increasing the effectiveness of the management of corporate property in Russia. In this regard, the work deals with general principles of good governance and analyzed their application for enterprise property management purposes. Keywords: modern economy, Russia, corporate economic governance JEL Classifications: D23, G30, O1

Quality of life of chronic kidney disease patients on renal replacement therapy

The study demonstrated the results of the comparative analysis of various types of renal replacement therapy effects on the quality of life patients with terminal stage of chronic kidney disease on the basis of standardized questionnaires. It has been shown that the quality of life is significantly improved after a kidney transplantation. At the same time, it has also been found that the introduction of home dialysis, epoetins, active metabolites of vitamin D, calcimimetics in the clinic care expanded the opportunities for the labor rehabilitation of the dialysis patients and made their quality of life comparable with the same of the kidney transplant recipients

Anemia in Chronic Kidney Disease and After Kidney Allotransplantation (Systematic Review)

Anemia in chronic kidney disease (CKD) has been recognized as a separate independent risk factor of cardiovascular (CV) events. The aim of the review is to provide a literature summary concerning early diagnosis and treatment of anemia in CKD that may be useful for clinicians and contribute to decrease CV mortality. Literature searches were made in such major databases as: PubMed, Medline, Embase, Cochrane Library, CINAHL, Wiley Online Library, Scopus, Web of Science, e-library, and website of WHO. This search encompassed original articles, systematic reviews, and meta-analyses relevant to CKD and anemia over recent 15 years. A total of 54 references from 562 reviewed articles were selected as they met to the search criteria (anemia and CKD, including diabetes mellitus, systemic diseases and post-transplant anemia). The publications included 27 randomized controlled trials, 20 experimental studies representing new data on the links of CKD anemia and cardiovascular risk markers (cytokines, Klotho, fibroblast growth factor (FGF-23), hyperglycemia, hypoalbuminemia and some others), 4 systematic reviews and 3 clinical practice guidelines. The main attention was devoted to the analysis of the studies provided an early diagnosis of anemia, an ability to minimize the factors contributing to its severity that have allowed to improve CV and total outcomes and to reduce costs of hospital treatment of CKD patients with anemia

ПРОФИЛАКТИЧЕСКАЯ ЭФФЕКТИВНОСТЬ ВАКЦИНАЦИИ ПРОТИВ ПНЕВМОКОККОВОЙ ИНФЕКЦИИ У ДЕТЕЙ С ХРОНИЧЕСКОЙ ЛОР-ПАТОЛОГИЕЙ

The article presents the results of study of clinical and immunological effectiveness of the application of the vaccine «Pneumo-23» for children of 3—7 years old, suffering from chronic nasopharyngeal ring diseases of pneumococcal etiology. The authors revealed reduction of the frequency of cases of the main disease exacerbation and cases of ARI adjoining. Reduction of the main clinical symptoms of chronic adenoiditis and chronic tonsillitis was registered. Number of specific IgMand IgGAT to PS of the vaccine doubled reliably.Представлены результаты изучения клинико-иммунологической эффективности использования вакцины «Пневмо-23» у детей 3—7 лет, страдающих хроническими заболеваниями носоглоточного кольца пневмококковой этиологии. Выявлено снижение частоты обострений основного заболевания, присоединения ОРЗ, уменьшение основных клинических симптомов хронического аденоидита и хронического тонзиллита, а также достоверный двукратный прирост специфических IgМ-АТ и IgG-АТ к ПС, входящим в состав вакцины «Пневмо 23».

Highly Sensitive Immunochromatographic Identification of Tetracycline Antibiotics in Milk

A rapid immunochromatographic assay was developed for the control of tetracycline (TC). The assay is based on the competition between immobilized TC-protein conjugate and TC in a tested sample for binding with polyclonal anti-TC antibodies conjugated to colloidal gold during the flow of the sample along a membrane strip with immobilized reactants. Conjugation of colloidal gold and the total immunoglobulin (IgG) fraction of polyclonal antibodies was used to increase the assay sensitivity to ensure low content of specific antibodies in the conjugate. This allowed effective inhibition of free TC and conjugate binding in the strip test zone. Photometric marker registration allows control of the reduction of binding, thereby enhancing detection sensitivity. The proposed assay allows TC to be detected at concentrations up to 20 ng/mL, exceeding the limit of detection of the known analogues, in a wide working range (more than two orders) of 60 pg/mL to 10 ng/mL, ensured through the use of polyclonal antibodies. The assay time is 10 min. The efficiency of the designed assay is shown to identify TC in milk; the degree of recovery of TC ranges from 90 to 112%. The precision of the concentrations measurements was no more than 10%

Assessment of emotional intelligence level in intercultural educational environment

Introduction. Currently, the training of professionally competent specialists is a priority in the higher education system. One of the productive creative approaches is the development of emotional intelligence (EI/EQ), which contributes to the development of emotional intercultural competence to accelerate adaptation in a new intercultural environment. Aim. The aim of the research is to empirically determine the level of emotional intelligence in the intercultural context for further improving work with students of the humanities and economics specialities and proposing new techniques that develop emotional intercultural competence. Methodology and research methods. The methodological basis of the research is the concept of developing emotional intelligence as an integral part of soft skills. To study the level of emotional intelligence, the authors used the Mark Daniel Self-Scoring Emotional Intelligence Tests, which are a compilation of tests designed to study the level of emotional intelligence and determine the strengths and weaknesses of the test takers. The methods of psycho-diagnostics, comparison and generalisation of the obtained results were used. The test results were analysed using the SPSS.27 statistical package. Results. The research results help to understand the psychological characteristics of students of the humanities and economics specialities, taking into account the cultural context, which makes it possible to predict the difficulties and problems faced by teachers in the process of work with this type of students, to more accurately determine the characteristics and motives of their behaviour and the characteristics of the professional development of the individual. It also helps to select the right curriculum to meet students’ needs. Scientific novelty. The scientific novelty of the research consists in supplementing the existing knowledge in the field of EI about the psychological characteristics of representatives of the humanities and economics specialities in the context of intercultural communication and further forecasting their development based on correctly selected teaching methods. Practical significance. The presented features of students of the humanities and economics specialities can be employed by teachers when interacting with them and organizing the educational process, taking into account their interests and needs, as well as adjusting the level of development of EI. The results obtained can be useful in the preparation of educational and methodological complexes specifically designed for the development of emotional intercultural competence.Введение. В настоящее время подготовка профессионально компетентных специалистов – приоритетная задача в системе высшего образования. Одним из продуктивных творческих подходов является развитие эмоционального интеллекта (EI/EQ), способствующего развитию эмоциональной межкультурной компетентности для ускорения адаптации в новой поликультурной среде. Цель исследования – эмпирическое определение уровня эмоционального интеллекта для дальнейшего совершенствования работы со студентами гуманитарных и экономических специальностей в условиях межкультурного контекста и предложение новых методик, развивающих эмоциональную межкультурную компетентность. Методология и методы исследования. Методологической основой исследования послужила концепция развития эмоционального интеллекта как составной части soft skills. В работе использовались тесты самооценки эмоционально интеллекта (Mark Daniel Self-Scoring Emotional Intelligence Tests), которые представляют собой компиляцию тестов для исследования уровня эмоционального интеллекта и определения слабых и сильных сторон тестируемых, а также методы психодиагностики, сравнения, обобщения полученных результатов. Анализ результатов тестирования производился в статистическом пакете SPSS.27. Результаты исследования помогают понять психологические особенности студентов гуманитарных и экономических специальностей с учетом межкультурного контекста, что дает возможность прогнозировать трудности и проблемы работы с данным типом обучаемых, более точно определить особенности и мотивы их поведения, особенности профессионального развития личности. Кроме того, это помогает выбрать правильную учебную программу, удовлетворяющую потребности представителей данного вида деятельности. Научная новизна исследования состоит в дополнении имеющихся знаний в области EI о психологических особенностях представителей гуманитарных и экономическихспециальностей в контексте межкультурной коммуникации и дальнейшего прогнозирования их развития на основе правильно подобранных методик обучения. Практическая значимость. Представленные особенности студентов гуманитарных и экономических специальностей могут быть использованы преподавателями при взаимодействии с ними и организации учебного процесса с учетом их интересов и потребностей, а также корректировки уровня развития EI. Полученные результаты могут быть полезны при подготовке учебно-методических комплексов, специально предназначенных для развития эмоциональной межкультурной компетентности.The authors express their sincere gratitude to the reviewers for their constructive comments and recommendations.Авторы выражают благодарность рецензентам за их конструктивные замечания и рекомендации