Acoustic control system in medicine

This article describes a device, which allows to control various elements using sound signals of different tones remotely. Its possible application are also described in various control systems

The Interaction of Plasma Sialylated and Desialylated Lipoproteins with Collagen from the Intima and Media of Uninvolved and Atherosclerotic Human Aorta

We have evaluated the binding of sialylated and desialylated lipoproteins to collagen isolated from the proteoglycan and musculoelastic layers of intima and media of uninvolved human aorta and atherosclerotic lesions. Comparing various collagen preparations from the uninvolved intima-media, the binding of sialylated apoB-containing lipoproteins was best to collagen from the intimal PG-rich layer. Binding of sialylated apoB-containing lipoproteins to collagen from this layer of fatty streak and fibroatheroma was 1.4- and 3.1-fold lower, respectively, in comparison with normal intima. Desialylated VLDL versus sialylated one exhibited a greater binding (1.4- to 3.0-fold) to all the collagen preparations examined. Desialylated IDL and LDL showed a higher binding than sialylated ones when collagen from the intimal layers of fibroatheroma was used. Binding of desialylated HDL to collagen from the intimal PG-rich layer of normal tissue, initial lesion, and fatty streak was 1.2- to 2.0-fold higher compared with sialylated HDL

TO THE QUESTION ABOUT PROSPECTS (UPCYCLE) OF ABANDONED COPPER-SULPHIDE PITS IN THE URALS

Relevance of the topic is due to concern of modern civilized society about the negative impact on the ecology of man-made mineral formations of the mining activity. Technogenic ores are represented by sludges, which are removed by groundwater from abandoned pits and rock dumps. They are deposited in surface watercourse and serve as a source of environmental disasters. They overfill natural and artificial sedimentation basin, and the mine waters carrying them threaten to increase acidity in protected reservoirs that serve as a source for drinking water for big cities. At the same time, in recent years, the industrial value of these sludges has been determined, and the technology has been developed for extracting non-ferrous metals and useful associated components from them. It is revealing that this ore sludge occur directly in alluvial and deluvial deposits of river valleys and ponds, which are also of industrial interest as a source of surface gold and industrial minerals – sand gravel mixes. The need for the extraction of large volumes of the latter is particularly relevant, since an extensive construction program is planned and implemented here. The purpose of this paper is to attract attention of business and the public to an economically advantageous project for the development of manmade copper-zinc ores from the abandoned pits of the Urals with a simultaneous solution of environmental problems. Methodology. The work was done by the authors using the results of their own research and materials in collaboration with the team of Nedra group Ltd. The result of the work. The authors have shown the presence of technogenic copper-zinc deposit within the territory of the Degtyarsky pit and predicted gold-bearing placers in addition to it. Conclusions. The main task of the study in the territory of the Degtyarsky pit is granting the licenses for the sites of Istok and Elchyovka; the estimated cost of engineering design and geological exploration with an evaluation of reserves of non-ferrous, noble metals and associated raw materials in sludge and alluvium-deluvium, as well as with the solution of environmental problems, ranges from 50–60 to 80 million rubles

The Interaction of Plasma Sialylated and Desialylated Lipoproteins with Collagen from the Intima and Media of Uninvolved and Atherosclerotic Human Aorta

We have evaluated the binding of sialylated and desialylated lipoproteins to collagen isolated from the proteoglycan and musculoelastic layers of intima and media of uninvolved human aorta and atherosclerotic lesions. Comparing various collagen preparations from the uninvolved intima-media, the binding of sialylated apoB-containing lipoproteins was best to collagen from the intimal PG-rich layer. Binding of sialylated apoB-containing lipoproteins to collagen from this layer of fatty streak and fibroatheroma was 1.4-and 3.1-fold lower, respectively, in comparison with normal intima. Desialylated VLDL versus sialylated one exhibited a greater binding (1.4-to 3.0-fold) to all the collagen preparations examined. Desialylated IDL and LDL showed a higher binding than sialylated ones when collagen from the intimal layers of fibroatheroma was used. Binding of desialylated HDL to collagen from the intimal PG-rich layer of normal tissue, initial lesion, and fatty streak was 1.2-to 2.0-fold higher compared with sialylated HDL

New Cytogenetic Photomap and Molecular Diagnostics for the Cryptic Species of the Malaria Mosquitoes Anopheles messeae and Anopheles daciae from Eurasia

The Eurasian malaria vector Anopheles messeae is a widely spread and genetically diverse species. Five widespread polymorphic chromosomal inversions were found in natural populations of this mosquito. A cryptic species, Anopheles daciae, was differentiated from An. messeae by the presence of several nucleotide substitutions in the Internal Transcribed Spacer 2 (ITS2) region of ribosomal DNA. However, because of the absence of a high-quality reference cytogenetic map, the inversion polymorphisms in An. daciae and An. messeae remain poorly understood. Moreover, a recently determined heterogeneity in ITS2 in An. daciae questioned the accuracy of the previously used Restriction Fragment Length Polymorphism (RFLP) assay for species diagnostics. In this study, a standard-universal cytogenetic map was constructed based on orcein stained images of chromosomes from salivary glands for population studies of the chromosomal inversions that can be used for both An. messeae and An. daciae. In addition, a new ITS2-RFLP approach for species diagnostics was developed. Both methods were applied to characterize inversion polymorphism in populations of An. messeae and An. daciae from a single location in Western Siberia in Russia. The analysis demonstrates that cryptic species are remarkably different in their frequencies of chromosomal inversion variants. Our study supports previous observations that An. messeae has higher inversion polymorphism in all autosomes than the cryptic species An. daciae

ALGORITHM OF THE SURGICAL TREATMENT FOR SPINAL TUMORS

The 571 patients with the tumors of cervical, thoracical and lumbar spine (159 patients with benging tumors, 35 - with primary malignant tumors and 377 - with metastatic lesion of the spine) have been treated surgically in 1997-2009. Tactics of surgical treatment of patients with a tumoral lesion of a column was based on an individual approach to each case of disease and depend on histological type of a tumor, localization, a degree of diffusion of process, presence of complications, age, a somatic state of the patient and sensitivity of a tumor to conservative methods of treatment