Pathologic dislocation of the shoulder secondary to septic arthritis: a case report

Septic arthritis of the shoulder is uncommon in adults, and complete dislocation of the glenohumeral joint following septic arthritis is extremely rare. We report a case of pathologic shoulder dislocation secondary to septic arthritis in an intravenous drug abuser

The effects of gradual vs. rapid weight loss on serum concentrations of myokines and body composition in overweight and obese females

Research has shown the modulations of Follistatin (FST) and Myostatin (MST) following weight loss. We evaluated the effects of gradual weight loss (GWL) and rapid weight loss (RWL) on serum MST, FST, and body composition in overweight and obese females. Thirty-six overweight and obese females successfully completed the study interventions: GWL (  = 18) or RWL (  = 18). Serum MST and FST concentrations, as well as anthropometric measurements, were collected at baseline and at the conclusion of each weight loss intervention. MST concentration significantly (  < .05) decreased in the GWL; while FST concentration, body fat percentage and skeletal muscle mass significantly declined in both conditions. The loss in skeletal muscle mass was significantly greater in RWL relative to GWL. GWL was more effective than RWL in preserving skeletal muscle mass in overweight and obese females. Moreover, GWL leads to declines in MST concentrations

Strategic Ingestion of High-Protein Dairy Milk during a Resistance Training Program Increases Lean Mass, Strength, and Power in Trained Young Males

Background: We evaluated the effects of high-protein dairy milk ingestion on changes in body composition, strength, power, and skeletal muscle regulatory markers following 6 weeks of resistance training in trained young males. Methods: Thirty resistance-trained young males (age: 27 ± 3 years; training experience: 15 ± 2 months) were randomly assigned to one of two groups: high-protein dairy milk (both whey and casein) + resistance training (MR; n = 15) or isoenergetic carbohydrate (maltodextrin 9%) + resistance training (PR; n = 15). Milk and placebo were ingested immediately post-exercise (250 mL; 30 g protein) and 30 min before sleep (250 mL; 30 g protein). Before and after 6 weeks of linear periodized resistance training (4 times/week), body composition (bioelectrical impedance), strength, power, and serum levels of skeletal muscle regulatory markers (insulin-like growth factor 1 (IGF-1), growth hormone, testosterone, cortisol, follistatin, myostatin, and follistatin–myostatin ratio) were assessed. Results: The MR group experienced a significantly higher (p 0.05) increase in lean mass, strength, and power (upper- and lower-body) than the PR group. Further, IGF-1, growth hormone, testosterone, follistatin, and follistatin–myostatin ratio were significantly increased, while cortisol and myostatin significantly decreased in the MR group than the PR group (p 0.05). Conclusions: The strategic ingestion of high-protein dairy milk (post-exercise and pre-sleep) during 6 weeks of resistance training augmented lean mass, strength, power, and altered serum concentrations of skeletal muscle regulatory markers in trained young males compared to placebo

Effect of the COVID-19 pandemic on the psychotropic drug consumption

International audienceImportance Although the COVID-19 pandemic has had a negative impact on mental health, there is no comprehensive longitudinal study of the entire population of a country without selection bias. Objective The objective of this study was to evaluate the prescription of psychotropic drugs during the COVID-19 pandemic, using data from the French national health data system (SNDS). Design, settings, and participants Prescriptions for psychotropic drugs (antidepressants, anxiolytics, hypnotics, and antipsychotics) from 1 January 2015 to 30 September 2021 were collected from administrative data provided by the SNDS. This database includes more than 99% of the French population, i.e., 67 million people. The data were analyzed using an interrupted time series analysis (ITSA) model. Main outcomes and measures Consumption of psychotropic drugs was aggregated in months and expressed in number of boxes per thousand inhabitants. Results During the study period, more than 1.3 billion boxes of psychotropic medications were dispensed. Comparison of psychotropic drug dispensing before and after the pandemic showed a relative increase of 0.76 (95 CI 0.57 to 0.95, p &lt;0.001) boxes per month per thousand inhabitants, all classes of psychotropic drugs combined. Three classes saw their consumption increase in an almost similar proportion, respectively, by 0.23 (0.15 to 0.32, p &lt;0.001) boxes for antidepressants, 0.27 (0.20 to 0.34, p &lt;0.001) boxes for anxiolytics and 0.23 (0.17 to 0.30, p &lt;0.001) boxes for hypnotics. The change in antipsychotic consumption was very small, with an increase of 0.04 boxes (0.02 to 0.06, p = 0.001) per month per thousand population. Conclusion and relevance The COVID-19 pandemic had led to an increase in the consumption of psychotropic drugs, confirming the significant impact of the pandemic on the mental health of the general population

The impact of job-demand-control-support on leptin and ghrelin as biomarkers of stress in emergency healthcare workers

Despite the available literature on the consequences of night shiftwork on stress and food intake, its impact on leptin and ghrelin has never been studied. We previously demonstrated that leptin and ghrelin were biomarkers related to stress, and acute stress-induced a decrease in leptin levels and an increase in ghrelin levels. We performed a prospective observational study to assess the influence of night work, nutrition, and stress on the levels of ghrelin and leptin among emergency healthcare workers (HCWs). We took salivary samples at the beginning of a day shift and/or at the end of a night shift. We also monitored stress using the job demand-control-support model of Karasek. We recorded 24-h food intake during the day shift and the consecutive night shift and during night work and the day before. We included 161 emergency HCWs. Emergency HCWs had a tendency for decreased levels of leptin following the night shift compared to before the dayshift (p = 0.067). Furthermore, the main factors explaining the decrease in leptin levels were an increase in job-demand (coefficient −54.1, 95 CI −99.0 to −0.92) and a decrease in job control (−24.9, −49.5 to −0.29). Despite no significant changes in ghrelin levels between shifts, social support was the main factor explaining the increase in ghrelin (6.12, 0.74 to 11.5). Food intake (kcal) also had a negative impact on leptin levels, in addition to age. Ghrelin levels also decreased with body mass index, while age had the opposite effect. In conclusion, we confirmed that ghrelin and leptin as biomarkers of stress were directly linked to the job demand-control-support model of Karasek, when the main cofounders were considered

Adaptation and use of amphipoda in fish culture ponds in order to increase fish production

Use and enrichment of live food resource in fish farms have been interested and highly demanded. Crustacean are one of the important groups. The Pontogammarus maeoticus dominated in southern Caspian Sea shore with a high abundance. This study was designed in order to adaptation and usage of amphipoda in fish culture ponds. The first part have been surveyed the laboratory experiments including of; to increasing and developing of P.maeoticus in 200 litter container, the effects of salinity on growth and survival of amphipods in many aquariums, the culture of common carp with amphipods and growth determination of them. Chemical composition analysis of P.maeoticus and carps fed by amphipods in compare to cultured carps from ordinary ponds. Due to concern about common healthy the heavy metal concentration has been measured in P. maeoticus, carp which were fed by amphipods and the cultured carps in earth ponds. In second phase; the adaptation of two amphipods species, P. maeoticus and Obesogammarus acuminatus was studied in fish ponds where some cages with sandy soft substrate had been provided for amphipoda replacement. Also a small surface of ponds surrounded by net and covered by Azola plant, a habitat suitable for to putting of O. acuminatus. Production of amphipoda had not the successfully results in large tanks. Aquariums with Caspian Sea water had the prosper results where the specimens were breeding and developing properly, even though in some aquarium with freshwater increased the amphipods number. The chemical composition had not significant difference between two kind of cultured carps while the organic component in amphipoda had a high quality. The better quality of cultured carp by amphipod diet have been confirmed by organoleptic test. The results of heavy metal measurement in amphipoda showed a high concentration which some of them were transmitted to cultured carps. Result of amphipoda replacement in cage was not satisfy and the specimens were died after some days. According to hydro-chemical parameters the oxygen poorness and high trophy levels were the affective factor to abolish of specimens in cages. It seems that there are many type of P.maeoticus that can be adapted in different salinities. The molecular differentiation should be investigated to choose the suitable type of this spices for utilization in freshwater fish ponds. In other hand it can be used in fish culture ponds that will be supplied by brackish water

Bio-ecological study of river estuaries in Guilan province

The Caspian Sea with brackish water is known as typical environment due to geo position, precious biota and the largest land-enclosed drainage area in the world. Macrobenthos were performed the main group of the Caspian Sea fauna. While they use as environmental bio-assessment, they have not completely studied in the Caspian Sea especially in estuaries environments. In this survey were studied eighteen river estuaries in Guilan province off Caspian sea southwest including Asrara, Chelevand, Lemir, Havigh, Shirabad, Khotbesara, Lisar, Karganroud, Navroud, Nokandekeh, Sefidrud, Heshmatrud, Langerud, Polerud and Chabokrud. The macro-invertebrate sampling was conducted seasonally at eight stations during autumn 2008 to autumn 2009. The macrobenthos organisms were identified as possible level in genus or species. The Shannon Wiener diversity and the Hilsenhoff biotic indices were used for evaluation of environmental quality. In this study, 69 genus identified that belong to 36 families and 16 orders. The most presentation of genus belongs to Chironomidae family with twenty six genus while others families were included forty three genus. The most average of macro-invertebrate abundance belong to order of Diptera with 35 %, subsequently the abundance of Amphipoda and Bivalvia orders occupied the second rank with 8.2 %. Orders Polychaeta, Oligochaeta and Cumacea had a low abundance during the study, however the Polychaeta showed a high abundance in some seasons and stations (up to 25%). The Plecoptera was rarely observed in some stations with high abundance. The Stenogammarus genus had the normally distribution during study, while Chironomidae genera as Eukifferiella and Cricotopus were measured in the high abundance during autumn 2008 to spring 2009. While Streblospio and Limnodrilus had the high presentation during winter and spring 2009, Cerastoderma sp. showed a high percentage in spring and summer 2009. The result of Shannon Wiener index values showed a significantly difference among regions for most seasons. There was also observed significantly difference for diversity values among stations in different seasons. According to Hilsenhoff biotic index for water quality classification; the most stations had good quality in spring 2009, while they were slightly and moderately good condition in winter 2009. The water quality of the Caspian Sea stations was in good condition as compared with the rivers estuary stations

Perceived discrimination based on the symptoms of covid-19, mental health, and emotional responses–the international online COVISTRESS survey

Background Despite the potential detrimental consequences for individuals’ health and discrimination from covid-19 symptoms, the outcomes have received little attention. This study examines the relationships between having personally experienced discrimination based on the symptoms of covid-19 (during the first wave of the pandemic), mental health, and emotional responses (anger and sadness). It was predicted that covid-19 discrimination would be positively related to poor mental health and that this relationship would be mediated by the emotions of anger and sadness. Methods The study was conducted using an online questionnaire from January to June 2020 (the Covistress network; including 44 countries). Participants were extracted from the COVISTRESS database (Ntotal = 280) with about a half declaring having been discriminated due to covid-19 symptoms (N = 135). Discriminated participants were compared to non-discriminated participants using ANOVA. A mediation analysis was conducted to examine the indirect effect of emotional responses and the relationships between perceived discrimination and self-reported mental health. Results The results indicated that individuals who experienced discrimination based on the symptoms of covid-19 had poorer mental health and experienced more anger and sadness. The relationship between covid-19 personal discrimination and mental health disappeared when the emotions of anger and sadness were statistically controlled for. The indirect effects for both anger and sadness were statistically significant. Discussion This study suggests that the covid-19 pandemic may have generated discriminatory behaviors toward those suspected of having symptoms and that this is related to poorer mental health via anger and sadness.info:eu-repo/semantics/publishedVersio

The influence of burnout on cardiovascular disease: a systematic review and meta-analysis

BackgroundBurnout is a public health problem with various health consequences, among which cardiovascular disease is the most investigated but still under debate. Our objective was to conduct a systematic review and meta-analysis on the influence of burnout on cardiovascular disease.MethodsStudies reporting risk (odds ratio, relative risk, and hazard ratio) of cardiovascular disease following burnout were searched in PubMed, PsycINFO, Cochrane, Embase, and ScienceDirect. We performed a random-effect meta-analysis stratified by type of cardiovascular disease and searched for putative influencing variables. We performed sensitivity analyses using the most adjusted models and crude risks.ResultsWe included 25 studies in the systematic review and 9 studies in the meta-analysis (4 cross-sectional, 4 cohort, and 1 case–control study) for a total of 26,916 participants. Burnout increased the risk of cardiovascular disease by 21% (OR = 1.21, 95% CI 1.03 to 1.39) using the most adjusted risks and by 27% (OR = 1.27, 95% CI 1.10 to 1.43) using crude risks. Using stratification by type of cardiovascular disease and the most adjusted risks, having experienced burnout significantly increased the risk of prehypertension by 85% (OR = 1.85, 95% CI 1.00 to 2.70) and cardiovascular disease-related hospitalization by 10% (OR = 1.10, 95% CI 1.02 to 1.18), whereas the risk increase for coronary heart disease (OR = 1.79, 95% CI 0.79 to 2.79) and myocardial infarction (OR = 1.78, 95% CI 0.85 to 2.71) was not significant. Results were also similar using crude odds ratio. The risk of cardiovascular disease after a burnout was not influenced by gender. Insufficient data precluded other meta-regressions.ConclusionsBurnout seems to increase the risk of cardiovascular disease, despite the few retrieved studies and a causality weakened by cross-sectional studies. However, numerous studies focused on the pathophysiology of cardiovascular risk linked to burnout, which may help to build a preventive strategy in the workplace

Study of Todebin dam reservoir in Zanjan province in order to aquaculture possibility

The Todebin dam reservoir has been constructed in central part of Abhar in the Zanjan province which has been studied with aquaculture purpose. This study was conducted on biotic and abiotic factors. The plankton, benthos and fishes were identified and the parasitology and bacteriology studies were performed on the lake fishes. Then the fisheries potential of the lake was calculated in respect of final fish farming amount and the fish releasing. The results showed the Bacillariophyta was dominated ِduring the study. the highest abundance of phytoplankton was between 2.1 and 12.5 million cells.l^-1 in the upper layer of lake as compared with the lower layer. The genus Cyclotella and Dinobryon belong to phytoplankton and Keratella and Polyathera belong to zooplankton were dominanted abundance. The mean biomass of benthos was varied from 5.5 to 29.5 g.m -2 and the Chironomidae had the most abundance. The ichtiology survey showed the presence of four cultured species and the Goldfish. The hydro-chemical results indicated no restriction for aquaculture activity. The oxygen average was more than 8 mg/l. The average of phosphate, nitrogen and hardness were measured 0.09±0.04, 2±0.8 and 237±94.5 mg/l., respectively. For the most hydrochemical factores, the values were significantly different between upper and bottom layers of the lake. The oxygen production and Chl-a amount were measured about 0.73 mg/l. and 7/03 µg/l., respectively. According to climatic restrictions, the cold fish culture is preferred than to culture of warm fishes. While the natural capacity of the lake was about 5 tones to warm fish culture, the fish production of trout was estimated about 40 tones. This volume will be available during four months periods and twice a year