РЕКОНСТРУКТИВНО-ПЛАСТИЧЕСКИЕ ОПЕРАЦИИ В КОМПЛЕКСНОМ ЛЕЧЕНИИ И РЕАБИЛИТАЦИИ БОЛЬНЫХ РАКОМ ПРЯМОЙ КИШКИ (КЛИНИЧЕСКОЕ НАБЛЮДЕНИЕ)

Today the colorectal cancer still one of the most common oncological disease in the World. Every Year diagnosed more then 1,4 mln new cases of colorectal cancer. Approximately 40% of them – able-bodied citizens. Nowadays we achieved good results in colorectal cancer treatment thanks to multidisciplinary treatment scheme. Actual problem is to preserve quality of life, especially after neoadjuvant chemoradiotherapy. A good known that after low rectal resection patient have a high risk of low anterior resection syndrome – LARS (fecal incontinence, diarrhea, tenesmus etc). The main factor for LARS – loss of reservoir function of the rectum, the most promising direction was the work on the formation of reservoir from the remaining intestine.В настоящее время колоректальный рак занимает одну из лидирующих позиций среди онкологических заболеваний в мире. Каждый год диагностируется более 1,4 млн новых случаев колоректального рака. Примерно 40% из них – трудоспособные граждане. В настоящее время благодаря внедрению программ комбинированного и комплексного лечения удалось достигнуть хороших результатов в лечении колоректального рака. Актуальной проблемой является сохранение качества жизни пациентов, особенно после неоадъювантной химиолучевой терапии в сочетании с оперативным лечением. Хорошо известно, что после проведения резекции прямой кишки имеется высокий риск развития синдрома низкой передней резекции (СНПР) – недержание кала, диарея, тенезмы и т.д. Основная причина СНПР – потеря резервуарной функции прямой кишки. Наиболее эффективным хирургическим методом профилактики СНПР является формирование толстокишечного резервуара

ECONOMIC EFFICIENCY OF THE IMPLEMENTATION OF THE PROGRAM OF CARDIOVASCULAR DISEASES MULTIFACTORIAL PREVENTION IN THE ORGANIZED COLLECTIVE OF TECHNICAL RESEARCH INSTITUTE

Aim. To estimate economic efficiency of a complex of resource-saving activities for cardiovascular diseases prevention at a workplace.Material and methods. The complex of activities including preventive examination and preventive intervention with their efficacy monitoring was performed in 523 people of a technical research institute staff. Preventive examination included evaluation procedures for cardiovascular diseases and their risk factors (89,5% of respondents). Preventive intervention based on risk factors modification was performed in intervention group. Control group included staff not participating in preventive consultation. Costs associated with cardiovascular diseases and risk factors (medical care consumption and temporary disability) and cost- efficiency analysis was performed.Results. High prevalence of arterial hypertension, metabolic and psychoemotional risk factors at workplace was found in preventive examination. Significant reduction in blood pressure (BP) and total cholesterol (TC) plasma level as well as a tendency to cardiovascular risk (CVR) decrease was reached due to preventive intervention. Costs associated with cardiovascular diseases and their risk factors in intervention group were lower than these in control group (168 584 and 489 500 rbl per 100 people yearly, respectively). Cost- efficiency analysis shown that costs of BP, TC plasma level and CVR reduction were moderate in intervention group. Costs were not efficient in control group.Conclusion. Implementation of cardiovascular diseases prevention at workplace is economically efficient both for society and for employer

The super fixed target beauty facility at the SSC

The rationale for pursuing beauty physics at the SSC in a fixed target configuration is described. The increased beauty production cross section at the SSC, combined with high interaction rate capability of the proposed detector, results in 1010-11 produced BB events per year. The long decay length of the B hadrons (all equal to10 cm) allows direct observation of B decays in the high resolution silicon microstrip vertex detector. To optimize the operation of the proposed beauty spectrometer and the SSC, parasitic extraction of attendant or artificially generated large amplitude protons using crystal channeling is proposed and explored. The large sample of fully reconstructed B events allows detailed studies various CP violating decays with requisite statistics to confront the standard model. The CP physics potentials of the proposed experiment is evaluated and compared with alternative approaches, such as asymmetric e+e- B Factories and specialized hadron colliders. © 1992