CREATION AND PHARMACOTECHNOLOGICAL INVESTIGATIONS OF INNOVATIVE DOSAGE FORMS OF MEXIDOL

The present study is devoted to the creation and study of transdermal dosage forms with mexidol and experimental substantiation of their therapeutic efficacy. The original technological scheme of production of one of the most popular structures transdermal - transdermal patches with mexidol. Selected efficient packaging, a shelf life of dosage forms. Developed, justified, biopharmaceutical research confirmed the optimal composition cohesive mass. Conducted optimal standardization of patches according to the most characteristic and important indicators. Studied local irritating effect and hipersensitivity proposed dosage form. Investigated and confirmed the ability of transdermal forms of mexidol to percutaneous transport

RANGE AND CHARACTERISTICS TRANSMUCOSAL DOSAGE FORMS

Currently, one of the promising methods of taking medications are instant formulations (in particular, medicinal films), which have a number of advantages over traditional dosage forms. In addition, the classification of rapidly dissolving films and their application are considered, and an assortment of transmucosal dosage forms is presented

Study of pharmaceutical properties of low-dosage enteric-coated acetylsalicylic acid

The article focuses on the brief content-analysis of pharmaceutical market, acetylsalicylic acid, applied in thrombosis prevention. During the study it was revealed that Thrombo ACC® drug fulfills the requirements of regulatory documents by the parameter test “Dissolution”. The quantitative study also performed for quantitative acetylsalicylic acid measurement in the Thrombo ACC® drug, under various storage and usage conditions. It was shown that if following the recommended conditions, acetylsalicylic acid amount in the drug does not change significantly