The Use of Silver Phenyl Benzyl Phosphate for the Synthesis of Monophenyl Esters of Phosphatidic Acids

Hessel, Morton, Todd, and Verkade have shown that dibenzyl esters of a-glycerophosphatidic acids I (D = acyl group), when shaken at room temperature in an ethanolic medium with hydrogen under slightly more than atmospheric pressure in the presence of a palladium/ active carbon catalyst according to Verkade, Cohen, and Vroege are smoothly hydrogenolyzed; 2 moles of hydrogen per mole of ester are rapidly absorbed, resulting in the formation of the corresponding phosphatidic acids and toluene

The Use of Silver Phenyl Benzyl Phosphate for the Synthesis of Monophenyl Esters of Phosphatidic Acids

Hessel, Morton, Todd, and Verkade have shown that dibenzyl esters of a-glycerophosphatidic acids I (D = acyl group), when shaken at room temperature in an ethanolic medium with hydrogen under slightly more than atmospheric pressure in the presence of a palladium/ active carbon catalyst according to Verkade, Cohen, and Vroege are smoothly hydrogenolyzed; 2 moles of hydrogen per mole of ester are rapidly absorbed, resulting in the formation of the corresponding phosphatidic acids and toluene