Creation of Digital Elevated Model using lunar images of Chandrayan – 1

The present work discusses the technique and methodology of analysing and Terrain Mapping Camera (TMC) Images acquired during India’s first  Moon mission, Chandrayaan  – 1, launched on October, 2008  for generating Digital Elevated Model (DEM). The Terrain Mapping Camera (TMC) on India’s first satellite for lunar exploration, Chandrayaan-1, is intended for systematic topographic mapping of the entire lunar surface, including the far side and the polar regions. A high resolution imagery of the entire Moon will help detailed study of specific lunar regions of scientific interests and further our understanding of lunar evolution. The swath of the instrument is 20 km. The digital elevation model (DEM) is a computer representation of the moon’s surface. DEMs can be generated by traditional photogrammetry based on aerial photos if they are available and they are created very often more economically by the means of space images. A Digital Terrain Model (DEM) is a continuous representation of a ground surface landform that is commonly used to produce topographic maps. DEMs are created by integrating data obtained from a wide range of techniques including remote sensing and land surveying.DEM's are sampled arrays of elevation values representing ground positions at regularly spaced intervals. Digital Elevation Model (DEM) is the terminology adopted by the USGS to describe terrain elevation data sets in a digital raster form.  The normal orientation of data is by columns and rows. In this project work a DEM is created for each of the lunar images retrieved from the space craft using Triangulated Irregular Network (TIN)Key Words : Chandrayaan-1, DEM, Swath, TMC, TINDOI:http://dx.doi.org/10.11591/ijece.v1i2.8

Virtual Screening of Drugs against HIV-1 Protease

The life-threatening infections and pandemic spread of Human Immunodeficiency virus-1 (HIV-1), the etiologic agent of AIDS, has promoted an unending scientific effort to understand and control the disease. The resultant understanding of HIV-1 life cycle has defined many different targets for potential drug intervention. HIV protease enzyme responsible for cleaving large polyprotein precursors into biologically active protein products is an important target for the treatment of AIDS. However drug resistance is a persistent problem and new protease inhibitors are needed. Tipranavir, one of the protease inhibitors most recently approved for clinical use has been shown to be potent against viruses harbouring multidrug resistance mutations such as V82A and L90M, but even this drug is shown to lose potency due to certain mutations or mutation patterns. Thus 10 derivatives of the drug Tipranavir, chemically diverse from the initial hit were generated and screened to determine their ability to interact with protease. Further analysis revealed one unique compound with high binding ability from the initial hit and its possibility for new class of protease inhibitors is discussed in this report

A VLSI Approach for Cache Compression in Microprocessor

Speed is one of the important issues that generally customers consider for selecting any electronic component in the market. Speed of a microprocessor based system mainly depends on the speed of the microprocessor which in turn depends on the memory access time. Accessing on chip memory takes more time than accessing off-chip memory. Because of these, designers of memory system may find cache compression as an advantageous method to increase speed of a microprocessor based system, as it increases cache capacity and off-chip bandwidth. The However, most past work, and all work on cache compression, has made unsubstantiated assumptions about the performance, power consumption, and area overheads of the proposed compression algorithms and hardware. It is not possible to determine whether compression at levels of the memory hierarchy closest to the processor is beneficial without understanding its costs. Proposed hardware compression algorithms fall into the dictionary-based category, which depend on building a dictionary and using its entries to encode repeated data values. Proposed algorithm has number of novel features like including combining pairs of compressed lines into one cache line and allowing parallel compression of multiple words while using a single dictionary and without degradation in compression ratio

Comparison of leaf volatile aroma constituents and phenolic acid profiles of the seedling originated polyembryonic mango (Mangifera indica L.) genotypes

In mango, leaf and fruit volatile aroma profiles are variety specific which can be used as fingerprint of a variety. Such biochemical markers can also discriminate the nucellar and zygotic seedlings in polyembryonic mango varieties. In order to validate the applicability of volatile as well as phenolic acid profiles as biomarkers, the open pollinated seedlings of three polyembryonic varieties of mango were compared with their mother trees. Leaf volatile and phenol acid profiling were done using Gas Chromatography/Mass Spectrometry (GCMS) and Liquid Chromatography/Mass Spectrometry (LCMS) methods respectively. The sesquiterpene hydrocarbons were the most abundant in all the genotypes studied. Monoterpenoids were the major compounds in cultivars Vellaikolumban and Olour, while the sesquiterpenoids were the major compounds in cv. Turpentine. While terpinolene was the major monoterpenoid compound in Vellaikolumban and limonene in cv. Olour, the sesquiterpene á-gurjunene was the major compound in cv. Turpentine. Volatile profiling showed clear differences between the varieties but was similar within a variety. Among the 15 phenolic acids quantified in the leaves, P-coumaric acid, gallic acid, and ferulic acids were predominant whereas, vanillic acid, syringic acid, gentisic acid, benzoic acid, and sinapic acids were low in quantity. Phenolic acid profile did not show significant diversity among the varieties and therefore cannot be used for identification of varieties. The volatile profiling can be used for the identification and differentiation of polyembryonic mango genotypes

Multiplier Based On Add And Shift Method By Passing Zero

In this paper, a low-power structure for shift-and-add multipliers is proposed. The architec-ture considerably lowers the switching activity of conventional multipliers. The modification to the multiplier which multiplies A by B include the removal of the shifting register, direct feeding of A to the adder, bypassing the adder whenever possible, using a ring counter instead of a binary counter and removal of the partial product shift. The architecture makes use of a low-power ring counter proposed in this work . The proposed multiplier can be used for low-power applications where the speed is not a primary design parameter

Effect of in situ Rainwater Harvesting and Mulching on Growth, Yield and Fruit Quality in Mango Var. Arka Neelachal Kesri in Eastern India

A field study was conducted at Central Horticultural Experiment Station (ICAR-IIHR), Bhubaneswar, India, during 2007-2013 in a new mango orchard of the variety 'Arka Neelachal Kesri' at 5m x 5m spacing, to conserve rain-water and to enhance soil moisture availability during dry periods for augmenting plant growth and fruit production. Among the four in situ rain-water harvesting techniques (cup-and-plate, half-moon, full-moon, and trench) evaluated in combination with three types of mulch (no mulch, inorganic mulch, and organic mulch), the cup-and-plate system resulted in maximum annual increment in vegetative growth and fruit yield (4.67kg/plant), while, organic (paddy straw) and inorganic (black polythene, 100μ thickness) mulches improved vegetative growth, fruit yield and TSS in fruit significantly over no mulch

Vitamin D receptor and interleukin-1 receptor antagonist gene polymorphism in spinal tuberculosis

Our earlier studies revealed that both MHC (Major Histocomptibility Complex) and non-MHC genes are associated with the susceptibility to pulmonary tuberculosis (TB). To find out whether non-MHC genes such as vitamin D receptor (VDR) and interleukin-1 receptor antagonist (IL-1RA) genes are associated with the susceptibility to spinal TB (extrapulmonary form of TB), the present study was carried out in spinal TB patients (n=66) and spouses of TB patients (spinal-TB and pulmonary-TB) ( n = 80) (family contacts). A trend towards an increased per cent genotype frequency of IL-1RA genotype variant 22 (12.1%) was seen in spinal TB patients when compared to the controls (3.8%) (spouses of the patients) (P=0.057; odds ratio 3.5). No difference was observed in the frequency of VDR genotypes between the overall spinal TB patients and the family contacts. However, the VDR mutant genotype tt was seen at a higher frequency in female patients with TB spine (TBS) (12.8%) than female contacts (4.2%) ( P >0.05 not significant; odds ratio 3.5). Among the contacts, a significantly increased frequency of wild type genotype TT (wild homozygotes) was seen in female contacts (55.1%) than male contacts (16.1%) (P =0.0012). Similarly a significant decrease in tt genotype was seen in female contacts (4.1%) than male contacts (25.8%) (P=0.012). The present study suggests that IL-1RA genotype 22 may be associated with the susceptibility to spinal TB. Moreover, vitamin D receptor tt genotype may be associated with the susceptibility to spinal TB in female patients. The study reveals that multicandidate genes may be associated with the susceptibility to spinal TB

Influence of non-MHC genes on lymphocyte response to Mycobacterium tuberculosis antigens and tuberculin status in Pulmonary tuberculosis

Background & objectives : Major histocompatibility complex (MHC) genes are known to influence the immune functions. In the present study, the influence of non-MHC genes such as mannose binding protein (MBP), vitamin D receptor (VDR) and interleukin-1 receptor antagonist (IL-IRA) gene polymorphisms on lymphocyte response to Mycobacterium tuberculosis culture filtrate antigen (10 μg/ml) was studied in 44 patients with active pulmonary TB and the family contacts (35) and in 32 normal healthy subjects. The influence of these gene polymorphisms on tuberculin (1TU of PPD of M. tuberculosis) reactivity status in 146 pulmonary TB patients was also studied. Methods : The MBP and VDR genes were amplified using polymerase chain reaction (PCR) and genotyping was carried out using sequence specific oligonucleotide probes by dot blot and IL-1RA by agarose gel electrophoresis. Results : A significantly decreased lymphocyte response to M. tuberculosis antigen was seen in pulmonary TB patients positive for functional mutant homozygotes of MBP (00) compared to heterozygote carriers (AO; P<0.02) and wild homozygotes (AA; P<0.01). The variant mutant genotype (tt) of VDR gene was associated with an increased lymphocyte response in control subjects compared to active TB patients with tt genotype (P<0.05). Heterozygote carriers of MBP (AO) were associated with a significantly (P<0.001) decreased tuberculin reactivity compared to wild homozygotes (AA). The VDR genotype Tt (heterozygote carrier) was associated with an increased tuberculin reactivity in female TB patients as compared to male patients (P<0.001). Interpretation & conclusions : The present study suggested that MBP and VDR genes influence the cell mediated immune response in pulmonary TB patients. Non-MHC genes along with HLA-Class II genes/gene products may be playing an immunoregulatory role in the mechanism of susceptibility/resistance to tuberculosis