Investigating the Structure of the Windy Torus in Quasars

Thermal mid-infrared emission of quasars requires an obscuring structure that can be modeled as a magneto-hydrodynamic wind in which radiation pressure on dust shapes the outflow. We have taken the dusty wind models presented by Keating and collaborators that generated quasar mid-infrared spectral energy distributions (SEDs), and explored their properties (such as geometry, opening angle, and ionic column densities) as a function of Eddington ratio and X-ray weakness. In addition, we present new models with a range of magnetic field strengths and column densities of the dust-free shielding gas interior to the dusty wind. We find this family of models -- with input parameters tuned to accurately match the observed mid-IR power in quasar SEDs -- provides reasonable values of the Type 1 fraction of quasars and the column densities of warm absorber gas, though it does not explain a purely luminosity-dependent covering fraction for either. Furthermore, we provide predictions of the cumulative distribution of E(B-V) values of quasars from extinction by the wind and the shape of the wind as imaged in the mid-infrared. Within the framework of this model, we predict that the strength of the near-infrared bump from hot dust emission will be correlated primarily with L/L_Edd rather than luminosity alone, with scatter induced by the distribution of magnetic field strengths. The empirical successes and shortcomings of these models warrant further investigations into the composition and behaviour of dust and the nature of magnetic fields in the vicinity of actively accreting supermassive black holes.Comment: 11 pages, 6 figures, accepted for publication in MNRA

Dopamine-D1 and δ-opioid receptors co-exist in rat striatal neurons

Cocaine’s enhancement of dopaminergic neurotransmission in the mesolimbic pathway plays a critical role in the initial reinforcing properties of this drug. However, other neurotransmitter systems are also integral to the addiction process. A large body of data indicates that opioids and dopamine together mediate emotional and reinforced behaviors. In support of this, cocaine-mediated increases in activation of dopamine D1 receptors (D1R) results in a desensitization of δ-opioid receptor (DOR) signaling through adenylyl cyclase (AC) in striatal neurons. To further define cellular mechanisms underlying this effect, the subcellular distribution of DOR and D1R was examined in the rat dorsolateral striatum. Dual immunoperoxidase/gold-silver detection combined with electron microscopy was used to identify DOR and D1R immunoreactivities in the same section of tissue. Semi-quantitative analysis revealed that a subset of dendritic cellular profiles exhibited both DOR and D1R immunoreactivities. Of 165 randomly sampled D1R immunoreactive profiles, 43% contained DOR. Similarly of 198 DOR-labeled cellular profiles, 52% contained D1R. The present data provide ultrastructural evidence for co-existence between DOR and D1R in striatal neurons, suggesting a possible mechanism whereby D1R modulation may alter DOR function