ИССЛЕДОВАНИЕ ОСТЕОПЛАСТИЧЕСКИХ СВОЙСТВ РЕЗОРБИРУЕМОГО ПОЛИ-3-ГИДРОКСИБУТИРАТА IN VIVO НА МОДЕЛЯХ СЕГМЕНТАРНОЙ ОСТЕОТОМИИ

A family of materials  based  on biodegradable polymer-3-hydroxybutyric acid (polyhydroxybutyrate, PHB) has been  developed for the purposes of reparative osteogenesis. Osteoplastic properties of bulk implants  PHB and PHB composition with hydroxyapatite (HA) have been  investigated in comparison with branded drugs Bio-Oss ® in vivo via the model of segmental osteotomy. It is indicated that  reconstructive bone  formation is more  active when implants  with PHB as a main component are used.Для целей  репаративного остеогенеза разработано семейство материалов на основе биоразрушаемого полимера-3-гидроксимасляной кислоты (полигидроксибутирата, ПГБ). Остеопластические свойства  объемных имплантатов из ПГБ и композиции ПГБ с гидроксилапатитом (ГАП) исследованы in vivo на модели сегментарной остеотомии в сравнении с фирменным препаратом Bio-Oss®.  Показано, что реконструктивный остеогенез происходит более активно  при использовании имплантатов, содержащих в качестве основного компонента ПГБ.

THE RESEARCH OF OSTEOPLASTIC PROPERTIES OF RESORBABLE POLY-3-HYDROXYBUTYRATE IN vIvO ON MODELS OF SEGMENTAL OSTEOTOMY

A family of materials  based  on biodegradable polymer-3-hydroxybutyric acid (polyhydroxybutyrate, PHB) has been  developed for the purposes of reparative osteogenesis. Osteoplastic properties of bulk implants  PHB and PHB composition with hydroxyapatite (HA) have been  investigated in comparison with branded drugs Bio-Oss ® in vivo via the model of segmental osteotomy. It is indicated that  reconstructive bone  formation is more  active when implants  with PHB as a main component are used

Three-dimensional energy channeling in the unit-cell model coupled to a spherical rotator II: unidirectional energy channeling

This work is the second one in a two-part series devoted to the analysis of complex nonlinear mechanism of energy channeling emerging in a locally resonant three-dimensional, unit-cell model, and the current paper considers unidirectional energy channeling. The considered system comprises an external mass subjected to a symmetric three-dimensional linear local potential with an internal spherical rotator. The present study specifically focuses on the analysis of three-dimensional, dissipative mechanism of irreversible (unidirectional) energy transport across mutually orthogonal directions realized in the limit of low-energy excitations. In particular, this study unveils the special transient regimes of three-dimensional partial and complete transformation of in-plane vibrations of the external element to out-of-plane vibrations. Similar to the results reported in the first part of the series, this three-dimensional energy flow is fully governed by the motion of the internal spherical rotator coupled to the external mass. Analysis of this peculiar response regime is based on regular multi-scale asymptotic analysis resulting in a reduced order dissipative slow-flow model. Results of the analysis are substantiated by the numerical simulations of the full model.by K. R. Jayaprakash and Yuli Starosvetsk

Breather solutions of the discrete p-Schrödinger equation

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