Additional file 1 of Midregional proatrial naturetic peptide (MRproANP) and copeptin (COPAVP) as predictors of all-cause mortality in recently diagnosed mild to moderate COPD—results from COSYCONET

Additional file 1: Table S1. Results of consecutive Cox regression analyses in all patients of grades GOLD 0-4. Hazard ratios are given for the respective biomarkers in the upper quartile versus the three lower quartiles. * Age, BMI, FEV1% predicted, TLCO % predicted, SGRQ total score, 6-minute walking distance, ≥1 moderate/severe exacerbations in the previous year, smoking status, pack years, hypercapnia (PaCO2 >55 mmHg), hypoxemia (PaO2 <60 mmHg). ** All variables of model 2 plus sex, hypertension, diabetes, hyperlipidemia, log HbA1c, and log CRP. *** All variables of model 3 plus heart failure, coronary artery disease, history of myocardial infarction, history of stroke, ankle-brachial index ≤0.90, log NT-proBNP, left-ventricular ejection fraction from echocardiography