Economic evaluation of road user related measures. Deliverable 4.3 of the H2020 project SafetyCube

Safety CaUsation, Benefits and Efficiency (SafetyCube) is a European Commission supported Horizon 2020 project with the objective of developing an innovative road safety Decision Support System (DSS). The DSS will enable policy-makers and stakeholders to select and implement the most appropriate strategies, measures, and cost-effective approaches to reduce casualties of all road user types and all severities. This document is the third deliverable (4.3) of work package 4, which is dedicated to the economic evaluation - mainly by means of a cost-benefit analysis - of road user related safety measures [...continues]

The European road safety decision support system on risks and measures

The European Road Safety Decision Support System (roadsafety-dss.eu) is an innovative system providing the available evidence on a broad range of road risks and possible countermeasures. This paper describes the scientific basis of the DSS. The structure underlying the DSS consists of (1) a taxonomy identifying risk factors and measures and linking them to each other, (2) a repository of studies, and (3) synopses summarizing the effects estimated in the literature for each risk factor and measure, and (4) an economic efficiency evaluation instrument (E3-calculator). The DSS is implemented in a modern web-based tool with a highly ergonomic interface, allowing users to get a quick overview or go deeper into the results of single studies according to their own needs

Identification of safety effects of infrastructure related measures, Deliverable 5.2 of the H2020 project SafetyCube

Identification of safety effects of infrastructure related measures, Deliverable 5.2 of the H2020 project SafetyCub

Inventory of assessed infrastructure risk factors and measures, Deliverable 5.4 of the H2020 project SafetyCube

Inventory of assessed infrastructure risk factors and measures, Deliverable 5.4 of the H2020 project SafetyCub

Plasma-activated liquid as a potential decontaminant in healthcare: assessment of antibacterial activity and use with cleaning cloths

Background: ; Cold air plasma (CAP) can generate plasma activated liquids (PALs) with high concentrations of reactive oxygen (ROS) and nitrogen species (RNS), e.g. nitrites, with antimicrobial properties. Aim: We investigated the concentrations of ROS and RNS in saline PAL. We assessed planktonic bacterial inactivation by PAL and the decontamination of contaminated cleaning cloths. Methods: Phosphate-buffered saline (PBS) was treated with an air-driven CAP jet for 90 or 300s to generate PAL. The ROS and RNS were measured using quantitative fluorescent (2,7-dichlorofluorescin diacetate) and colorimetric (Greiss) assays. Isolates of MRSA and E. coli were incubated in PAL overnight and inactivation measured through colony forming unit (CFU) assays. Sections of cleaning cloths were incubated with MRSA and E. coli, and treated with PAL for 1 hour. Bacterial inactivation was measured through resazurin reduction assays. Results: Nitrites increased from 0.1 μM in untreated PBS to 49.1 μM and to 94.0 μM in 90 and 300s CAP-treated PAL, respectively. ROS increased from 30 μM in untreated PBS to 75 μM and to 103 μM in 90 and 300s CAP-treated PAL, respectively. 90s-PAL reduced MRSA and E. coli viability (p Conclusion: Inactivation of planktonic bacteria correlated with ROS and RNS concentrations. PAL reduced bacteria contaminated cleaning cloths. PAL has potential as a hospital disinfectant, including cleaning cloths.</p

Costs related to serious injuries, deliverable 7.3 of the H2020 project SafetyCube

Costs related to serious injuries, deliverable 7.3 of the H2020 project SafetyCub