A prospective evaluation of the feasibility and utility of additional tools to obtain information from recently diagnosed HIV infected patients

QUESTION UNDER STUDY: Can additional information be obtained from recently HIV diagnosed individuals? METHODS: A 1-year prospective Swiss study, including all newly diagnosed HIV-infected patients. Information on circumstances of HIV infection was collected through physician- and patient questionnaires and patient interviews. Information on timing of infection was linked with an HIV-antibody avidity assay. RESULTS: Of 710 newly HIV diagnosed patients, 543 (76%) physician questionnaires (PhyQ) and 145 (20%) patient questionnaires (PaQ) were returned. PhyQ required fewer reminders (57% vs 28% spontaneous return). Patients whose doctors had returned the PhyQ were comparable to total population group. In contrast, a strong bias towards well educated recently infected Swiss men having sex with men (MSM) was seen in patients returning PaQ or agreeing to an interview. 83% of patients claimed that they knew the infection source and 85% infection place. Unprotected sexual contact was the most frequently cited infection source (92%; n = 404). Men mainly claimed occasional (43%) and women steady (61%) partners as the most likely source of HIVinfection. Serum for timing of infection was available in 98% of patients. Recent infections (RI) were highest in MSM (51%) and intravenous drug users (IDU, 54%). Compared to women, heterosexual men were more than twice as likely to be diagnosed with a RI. CONCLUSION: Relevant additional information on circumstances of HIV infection in newly diagnosed patients can easily be collected from treating physicians. Collecting information from patients is not a feasible option, with the exception of qualitative interviews in a selected group of patients

Factors affecting diet, habitat selection and breeding success of the African Crowned Eagle Stephanoaetus coronatus in a fragmented landscape

This study aimed to identify variables that affect habitat selection and nesting success of the African Crowned Eagle Stephanoaetus coronatus, the largest forest raptor, in north-eastern South Africa. A preference for nesting in the Northern Mistbelt Forest vegetation type was established and 82% of all nests were located in indigenous trees. Nest abandonment was less common when distances to the nearest neighbour were greater. The diet of this species was investigated by examination of prey remains beneath nests and verified by comparison with museum specimens. In total, 156 remains were found, representing a minimum of 75 prey individuals. The diet of African Crowned Eagles constituted almost entirely mammals (99%), which were predominantly antelopes (61%) and monkeys (25%). It was also found that the proportion of primates in the diet correlates with latitude: populations in equatorial latitudes have a higher proportion of primates in their diets, whereas further south antelopes are a much more common diet component

Fluorescent Pigment and Phenol Glucosides from the Heartwood of Pterocarpus marsupium

The fluorescence shown by extracts of the heartwood of Pterocarpus marsupium is attributed to salts of the new compound 1, whose structure was elaborated using detailed spectroscopic/ spectrometric studies. The plant material also contains the nonfluorescent compounds 2 and 3. The absolute configuration of 1 was determined by experimental and theoretically calculated electronic CD spectra, while that of 3 was deduced from ECD comparison with reported results in the α-hydroxydihydrochalcone series

Additions to the bird list of the Golden Gate Highlands National Park

Additions to the bird list of the Golden Gate Highlands National Par

Rheumatologists' opinions on the feasibility of a measurement feedback system in rheumatoid arthritis and the influence of motivation.

Item does not contain fulltextOBJECTIVE: To assess rheumatologists' opinions about the feasibility of a measurement feedback system in rheumatoid arthritis (RA) and to analyse if motivational aspects play a role in assessing the value of the system and in determining the extent to which it is used. METHODS: A survey sample (n=105) was randomly selected from participants of a measurement feedback system. A survey questionnaire assessed opinions on system outcome, structures and processes, motivation and overall satisfaction. Survey results are given descriptively and groups differing in motivation are compared. RESULTS: The overall response rate was 62%. The system was generally perceived to fulfil its aims, but the effort required to use the system was rated less positive. Rheumatologists had as their motivation either 'science/obligation' or 'individual patient evaluation'. Rheumatologists with the latter motivation were more satisfied with the measurement feedback system, perceived its feasibility as better, and made more use of it. CONCLUSION: Motivation for participating in a measurement feedback system has a significant impact on overall satisfaction with the system and the use of the system. Influencing motivation and reduction of the amount of effort required to use the system might increase overall acceptance

Application of a soil quality triad in assessing ecological risk posed to croplands

Healthy soil ecosystems fulfil multiple functions (e.g. cycling nutrients and controlling pests), which play an important role in sustainable food production. However, the application of polluted irrigation water poses a major risk to soil quality (health) and warrants investigation to ultimately inform decision-making. We hypothesised that the standardised soil quality TRIAD approach (ISO 19204), which integrates the chemistry, ecology, and ecotoxicology lines of evidence, can be used as part of an ecological risk assessment of cropland soils. To investigate the applicability of this approach in an agricultural setting, we collected soils from croplands associated with the Hartbeespoort and Crocodile (West) irrigation schemes, which utilise water known to be heavily impacted by anthropogenic (metal, nutrient, and salt) pollution. Croplands associated with the Marico-Bosveld Irrigation Scheme served as the reference systems. Data from the three lines of evidence were scaled, weighted, and integrated. Moderate risk was evidenced for nutrient and salt content in most croplands associated with the Hartbeespoort Irrigation Scheme. However, either no or low risk was recorded for the ecology and ecotoxicology lines of evidence. Finally, the integrated risk assessment concluded that only low ecological risk was posed to soil quality, likely as a result of agricultural activities (e.g. tillage and fertiliser application) that deteriorated soils also at the reference system. This study shows important limitations in the application of ecological risk assessments in conventionally farmed soils, but still holds promise for organic and conservation systems. Significance: A pollution linkage between irrigation water and cropland soils was evidenced, but presented only minimal risk to soil quality. Conventional agricultural practices (e.g. tillage) mask the risk posed by environmental pollution and impair the applicability of ecological risk assessments. It is possible that this approach can be applied in less disturbed crop production systems, for example in conservation (regenerative) and organic croplands