Enterosorbtion therapy of acute intestinal infections with invazive type of the diarrhea in infants

In recent years, have not lost their relevance bacterial intestinal infections in infants. Infectious enterocolitis in infants occur mainly in moderate form, but often with symptoms of hem ocolitis and with long bacterioexcretion. The purpose of the study is definition of clinical efficiency of therapy for bacterial enteric infection with invasive type of diarrhea. Turning Mukofalk ® (phytosorbents) in pathogenic treatment 45 children with bacterial intestinal infections lead to a reduction duration of infectious toxicity, diarrhea and hemocolitis. Clinical efficiency Mukofalk ® confirmed decrease leukocyte index of intoxication by JJ Kalf-Caliph and BA Reys, im provement the coprologyc analyses.В последние годы не потеряли своей актуальности бактериальные кишечные инфекции у детей раннего возраста. Инфекционные энтероколиты у детей раннего возраста протекают преимущественно в среднетяжелой форме, но зачастую с явлениями гемоколита, а также с продолжительным бактериовыделением. Цель исследования. Определение клинической эффективности энтеросорбционной терапии при бактериальных кишечных инфекциях с инвазивным типом диареи. Включение Мукофалька® (фитосорбента) в патогенетическое лечение 35 детей с бактериальными кишечными инфекциями приводило к сокращению длительности инфекционного токсикоза, диареи и гемоколита. Клиническая эффективность Мукофалька® подтверждена снижением лейкоцитарного индекса интоксикации по Я.Я. Кальф -Калифу и Б.А. Райсу, улучшением копрологических данных

Study on cosmogenic activation above ground for the DarkSide-20k project

The activation of materials due to the exposure to cosmic rays may become an important background source for experiments investigating rare event phenomena. DarkSide-20k is a direct detection experiment for galactic dark matter particles, using a two-phase liquid argon time projection chamber filled with 49.7 tonnes (active mass) of Underground Argon (UAr) depleted in 39Ar. Here, the cosmogenic activity of relevant long-lived radioisotopes induced in the argon and other massive components of the set-up has been estimated; production of 120 t of radiopure UAr is foreseen. The expected exposure above ground and production rates, either measured or calculated, have been considered. From the simulated counting rates in the detector due to cosmogenic isotopes, it is concluded that activation in copper and stainless steel is not problematic. Activation of titanium, considered in early designs but not used in the final design, is discussed. The activity of 39Ar induced during extraction, purification and transport on surface, in baseline conditions, is evaluated to be 2.8% of the activity measured in UAr from the same source, and thus considered acceptable. Other products in the UAr such as 37Ar and 3H are shown to not be relevant due to short half-life and assumed purification methods