Endometriosis and ART outcome: a retrospective analysis

Background: Endometriosis affects up to 30-40% of women seeking fertility treatment and is known to reduce fecundity. There remains a debate on the effect of endometriosis on the IVF outcome, with live birth not reported in most studies. This study looks at the impact of endometriosis on live birth rates after IVF and compares the chances of success with those without endometriosis.Methods: Retrospective analysis of women who underwent IVF at our institution for 2 years were included. Multiple factor infertility, ovulation disorders and donor program were excluded. The outcomes were compared for 4 cohorts - women with endometriosis, male factor infertility, tubal factor infertility and unexplained infertility. The primary outcome was live birth rate. Other outcome measures were total dose of gonadotropins used, mean number of oocytes collected, M2 oocyte rate, fertilization rate, implantation rate, and clinical pregnancy rate.Results: Patients diagnosed with endometriosis had lower mean number of oocytes collected (6.86 vs 7.69, 7.94, 7.45) and lower mean number of M2 oocytes (5.31 vs 6.21, 6.44, 5.91) but was not statistically significant. Endometriosis patients required significantly higher dose of gonadotropins when compared to controls (5365.79 IU;  p-0.001). The per ET implantation rate (10.4% vs 17.8%, 22.5%, 19.2%), clinical pregnancy rate (8% vs 15%, 20%, 17%), live birth rate (7.92% vs 16.6%, 15.14%, 12%) and the cumulative live birth rate (27.9% vs 46.5%, 60%, 46.7%) were significantly less in women with endometriosis (p-0.039, p-0.021, p-0.001, p-0.039 respectively) and the effect is more pronounced with increasing disease severity.Conclusions: Endometriosis affects all aspects of IVF outcomes including folliculogenesis, embryo development and implantation. Though ovarian factor can be overruled by increasing the stimulation doses as in our study, methods to improve the implantation rates should be thought about in future.

Current Status of Solar Home Systems in Bangladesh

No abstract available

SEASONAL PREVALENCE OF Schistosoma spindale IN RUMINANTS AT CHENNAI

ABSTRACT A systematic survey was conducted during [2003][2004][2005][2006][2007

PURIFICATION AND CHARACTERIZATION OF EXCRETORY/ SECRETORY ANTIGENS OF FASCIOLA GIGANTICA

ABSTRACT Excretory/ Secretory (E/S) antigen of adult used for the purification of E/S antigen. A total of 6.4 mg of E/S antigen was obtained from the 60 flukes collected from slaughter houses. SDS-PAGE analysis of E/S antigen revealed 7 polypeptide bands a

Evaluation of mammogram findings of breast lesions with trucut biopsy

Introduction: Breast cancer is the most common malignancy in women and second leading cause of cancer death among women aged 20 to 59 years. Radiological assessment of the breast lesion by diagnostic mammography remains one of the key investigation in the so called triple assessment of breast lesions. Classification of the mammogram findings as BI-RADS score also helps in the study of the lesions by categorising it into benign, suspicious of and suggestive of malignancy[1]. Comparing its results with the gold standard histopathological (TRUCUT) findings confirms the diagnosis and helps to assess the reliability of mammogram in diagnosing the pathology. Materials and methods: A cross sectional study was conducted among 66 patients who has clinically suspicious malignant breast lesions, attending the General surgery OPD, Casualty, wards of Calicut medical college during the study period. Statistical analysis of the data performed, results of mammogram and trucut biopsy results are compared and analysed. Results: On comparing the mammographic findings to that of the Trucut results 96.96% turned out to be true positive and the rest 3.03% as false positive. Out of the false positive results all were in the category BI-RADS 4a, low suspicion of malignancy (2-9%). In the present study, because the inclusion criteria is “the lesion which are suspicious of malignancy” hence the study population includes only those with results of BIRADS IV - V but not the other categories. Conclusion: Since Mammogram helps in easily identifying the breast lesions, even the impalpable ones, also assess the multicentricity and helps in characterisation of breast lumps, results being reproducible and less subjective and non invasive, it can be considered a primary diagnostic tool in the evaluation of breast lesions and a reliable and useful tool in differentiation of malignant and benign breast masses

Laurence- Moon- Bardet- Biedle Syndrome – A Case Report

Laurence Moon Bardet Biedle syndrome is a rare, autosomal recessive genetic disorder. It has got wide spectrum of clinical features.Spastic paraplegia is predominant feature in Laurence Moon syndrome and polydactyly and obesity are predominant features in Bardet Biedle syndrome. Pigmentary retinal degeneration, mental retardation and hypogonadism are common to both. We report a case of 7 year old female who presented to us with complaints of night blindness. She showed all ocular features, most of the general features of Laurence Moon Bardet Biedl syndrome and a typical family history

Traffic Identification Method Engine : An open platform for Traffic classification “,”,

ABSTRACT: The availability of open supply traffic classification systems designed for each experimental and operational use will facilitate collaboration, convergence on normal definitions and procedures, and reliable analysis of techniques. during this article, we tend to describe Traffic Identification Engine (TIE), associate open supply tool for net-work traffic classification , that we tend to started developing in 2008 to market sharing common implementations and information during this field. In the traffic identification engine we use to special path or send messeges. in this algorithm we have the lowest path of width to send messages. Through scientific collaborations, and thanks to the support of the open source community, this platform gradually evolved over the past five years, supporting an increasing number of functionalities, some of which we highlight in this articles

Digital Image Steganography With Error Correction on Extracted Data

The hiding capacity (HC), imperceptibility, and security are the 3 important quality measures for a steganography technique. While the stego-image is on transit on the internet, the hidden data may be changed because of various reasons. The existing techniques does neither focus on detecting the errors in the data nor to correct the errors in data. Therefore, this article brings forward a steganography technique, wherein error detection and correction can be performed at recipient side. The original image is logically sliced into $2\times 2$ disjoint blocks. From these 4 pixels, 4 quotients and 4 least significant bits (LSBs) are generated. Each quotient is the decimal value of 7 most significant bits (MSBs) of a pixel. In every block 8 data bits can be camouflaged. From the 8 data bits, 4 redundant bits are computed using modified Hamming code. The 8 data bits and one redundant bit are camouflaged in the quotients by either quotient value differencing (QVD) or bit substitution. If camouflaging is performed in quotients using QVD, then indicator bit is set to1. Otherwise, if camouflaging in quotients is performed using bit substitution, then indicator bit is set to 0. The 3 remaining redundant bits along with the indicator bit are stored in the LSBs of the 4 pixels. At the receiver side, data could be extracted, and error correction procedure could be applied to correct 1-bit error over the 8 bits of data extracted from a block. From the experimental reports it could be concluded that the errors in the retrieved data at the recipient can be detected and corrected without reducing the HC and without increasing the distortion