11 research outputs found
A twist in chiral interaction between biological helices
Get PDFUsing an exact solution for the pair interaction potential, we show that
long, rigid, chiral molecules with helical surface charge patterns have a
preferential interaxial angle ~((RH)^1/2)/L, where L is the length of the
molecules, R is the closest distance between their axes, and H is the helical
pitch. Estimates based on this formula suggest a solution for the puzzle of
small interaxial angles in a-helix bundles and in cholesteric phases of DNA.Comment: 7 pages, 2 figures, PDF file onl
Halogen Substituents in the Isoquinoline Scaffold Switches the Selectivity of Inhibition between USP2 and USP7
No full textCap-dependent mRNA translation and the ubiquitin-proteasome system cooperate to promote ERBB2-dependent esophageal cancer phenotype
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Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma
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