DEVELOPMENT OF MARKETPLACES IN THE CONTEXT OF DIGITAL TRANSFORMATION AS A RESULT OF STRUCTURAL SHIFTS IN THE ECONOMY

Globalization and increased volatility of global markets, as well as increased competition, lead to the need for the business community to create new sustainable business models that are less susceptible to the negative effects of globalization. The sustainability of business models is determined by the effective use of resources: natural, material, financial and intellectual. The result of the transformation is the transition to network interaction and the formation of ecosystems of suppliers, partners, consumers and competitors around the business sphere. The main conclusions of the research paper are reduced to the need to achieve a comprehensive development of the digital economy, taking into account the interrelationships of economic processes and structural transformations. In this regard, the analysis of the relationship and principles of structural shifts in economic processes against the background of digital transformation becomes particularly relevant

Elliptical motions of stars in close binary systems

Motions of stars in close binary systems with a conservative mass exchange are examined. It is shown that Paczynski-Huang model widely used now for obtaining the semi-major axis variation of a relative stars orbit is incorrect, because it brings about large mistakes. A new model suitable for elliptical orbits of stars is proposed. Both of reactive and attractive forces between stars and a substance of the flowing jet are taken into account. A possibility of a mass exchange at presence of accretion disk is considere

ПОСЛЕДСТВИЯ ПРЕДПОСЕВНОГО ВОЗДЕЙСТВИЯ НИЗКИХ И ПЕРЕМЕННЫХ ТЕМПЕРАТУР НА СЕМЕНА МОРКОВИ И РЕДИСА

The study of the dynamics of plant growth and yield of vegetable crops (carrot variety Absheron winter (Daucus carota subsp. sativus (Hoffm.) Schьbl.) and radish variety Virovsky white (Raphanus sativus var.radicula Pers.)) was conducted in the field conditions after presowing exposure to different temperatures: I option – sowing of seeds exposed to low temperatures (for 15 days the swollen for 24 hours seeds were kept at a temperature of 0±1°С); Option II - sowing of seeds exposed to variable temperatures (for 5 days, the swollen for 24 hours seeds were exposed to variable temperatures of + 20°C (8 hours) and 0±1°C (16 hours) and then 10 days at a temperature of 0±1°C; K1 – sowing dry seeds; K2 – sowing soaked seeds. The impact on the seeds of low and variable temperatures caused an increase in growth processes, both in radish and carrot. Both studied crops showed a tendency to increase the yield to a greater extent when exposed to swollen seeds with variable temperatures. Thus, the average weight of radish crops exceeded the control variant by 47.1% and carrots by 27.6%. The yield of root crops per m2 increased by 36.4% for radish and 30.0% for carrot. To increase the productivity of vegetable crops, we recommend using the studied methods of pre-sowing seed treatment in practice.Изучение динамики роста растений и урожайности овощных культур: местного сорта моркови столовой – Апшеронская зимняя (Daucus carota subsp. sativus (Hoffm.) Schьbl.) и сорта редиса посевного – Вировский белый (Raphanus sativus var. radicula Pers.)) в полевых условиях проводили после предпосевного воздействия разных температур: I вариант – посев семян, подвергнутых действию низких температур (набухшие за 24 часа семена содержали при температуре 0±1°С в течение 15 суток); II вариант – посев семян, подвергнутых действию переменных температур (набухшие за 24 часа семена подвергали воздействию переменных температур 20°С (8 часов) и 0±1°С (16 часов) в течение 5 суток и затем при температуре 0±1°С в течение 10 суток); контрольные варианты: К1 – посев сухих семян; К2 – посев замоченных при температуре 20°С в течение 24 часов семян. Эффективность воздействия на семена низкими и переменными температурами выражалась в усилении ростовых процессов, как у редиса, так и у моркови. У обеих изучаемых культур наблюдалась тенденция к увеличению урожая в большей степени при воздействии на набухшие семена переменных температур. Так, средняя масса корнеплодов редиса превысила показания контрольного варианта (посев сухих семян) на 47,1%, а у моркови – на 27,6%. Урожайность корнеплодов с м2 увеличилась на 36,4% – у редиса и на 30,0% – у моркови. Для повышения урожайности овощных культур рекомендуем использовать изученные методы предпосевной обработки семян в практике

The Experience of Implementation of Innovative Technology of Quarry Waste Water Purifying in Kuzbass Open Pit

Among all industries in Kuzbass (Western Siberia, Russia) the coal industry provides the most environmental threat. However, the construction of new and maintenance of existing open pit mines do not often correspond to the tasks of improving the environmental safety of surface mining. So the article describes the use of innovative quarry waste water purifying technology implemented in Kuzbass open pit mine "Shestaki". This technology is based on using artificial filter arrays made of overburden rock

Лапароскопически-ассистированное устранение послеоперационного осложения чрескожной эндоскопической гастростомии

Percutaneous endoscopic gastrostomy (PEG) is widely used in a group of patients with dysphagia syndrome who require nutritional support with enteral nutrition. In the above observation, a severe complication of PEG is secondary non-circumscribed serous-purulent peritonitis, which developed in connection with the failure of PEG, against the background of cachexia, hypoproteinemia and hypercatabolism. The operation of choice was video laparoscopic surgery, revision and sanitation of the abdominal cavity was performed. The main stage of the operation was gastropexy (the stomach wall to the parietal peritoneum) with three vicryl sutures, which made it possible to seal the gastrostomy area. Чрескожная эндоскопическая гастростомия (ЧЭГ) получила широкое применение в группе пациентов с синдромом дисфагии и требующих нутриционной поддержки энтеральным питанием. В приведенном наблюдении тяжелое осложнение ЧЭГ — вторичный неотграниченный серозногнойный перитонит, развившийся в связи с несостоятельностью ЧЭГ, на фоне кахексии, гипопротеинемии и явлений гиперкатаболизма. Операцией выбора стала видеолапароскопическая операция, в ходе которой была выполнена ревизия и санация брюшной полости. Основным этапом операции стала гастропексия (стенки желудка к париетальной брюшине) тремя викриловыми швами, что позволило герметизировать область гастростомы.

Difficulties in differential diagnosis between obstructive and non-obstructive azoospermia

Introduction. The difference between obstructive and non-obstructive azoospermia (OA and NOA) is important for the choice of treatment tactics and adequate counseling of a married couple.Objective. To describe, analyze, and classify possible challenges in differentiating between two types of azoospermiaMaterials and methods. The retrospective review of database on surgical sperm retrieval attempts performed our hospital (n = 754). A subpopulation of 216 patients who were preliminary diagnosed with OA, was selected for further analysis. All patients had testicular pathology data following sperm retrieval attempt. Rate of reclassification was assessed as a primary outcome. Reclassified cases were further analyzed to find a possible reason for incorrect differential diagnosis.Results. Among 216 patients with initially suspected OA, 131 (60.6%) had evidence of spermatogenic dysfunction on pathological examination of seminiferous tubules. Multivariate regression analysis showed that only regular exposure to high temperatures was an independent predictor of NOA detection in patients with normal endocrine and clinical parameters (OR = 1.989; 95% CI = 1.101 – 3.595). Analysis of the decision tree showed that patients with inhibin B levels below 93 pg/ml had the highest risk of an incorrect initial diagnosis (82.6%).Conclusions. Differential diagnosis of OA and NOA is not such a simple task. Any case of azoospermia against the background of normal semen volume by default should be considered as a case of NOA if there is no anamnestic or clinical data clearly indicating obstruction. Regular exposure to high temperature is likely to cause azoospermia in men with initially severe disorders of spermatogenesis. Finally, the reference values of inhibin B offered by most laboratories are not intended to assess reproductive function

Innovative Technics of Managing Engineers' Global Competencies

Higher education modernization in the CIS countries takes place under the conditions of dynamic changes in economy and society. These changes are determined by the social and economic development of the country and the world globalization processes - cross-border intercultural communication, knowledge transparency, and the establishment of information society. Educational globalization is a continuous process of creating a unified global educational system, in which the distinctions between its member educational systems are being blended

Влияние ограниченных ожогов кожи на течение и исход ингаляционной травмы

Introduction Inhalation injury (ini) makes burn disease more severe. However, it remains unexplored what is the minimum area of the burn that can significantly aggravate of the course of ini.The objective was to compare the incidence of acute respiratory failure (arf), pneumonia, and mortality between patients with ini and ini with superficial skin burns up to 3% total body surface area (tbsa).Material and methods 125 patients with ini and i–ii degree skin burns up to 3% tbsa were allocated into 4 groups: ini without skin burns, ini with burns up to 1% tbsa, up to 2%, and up to 3% tbsa.Results In the group with ini and skin burns up to 2%, the number of arf, pneumonia cases, and deaths did not statistically significantly differ from the ini group, however in group of ini and burns of more than 2% tbsa, there were more of those complications.Conclusion Skin burns of i–ii degree over 2% tbsa increase the incidence of acute respiratory failure, pneumonia, and death in patients with ini.РЕЗЮМЕ Известно, что ингаляционная травма (ИТ) ухудшает течение ожоговой болезни у тяжелообожженных. Однако остается неизвестным, как небольшие ожоги влияют на течение ИТ.ЦЕЛЬ Сравнительное изучение частоты острой дыхательной недостаточности (ОДН), пневмонии и смертельных исходов у пациентов с ИТ и ИТ с поверхностными ожогами кожи до 3% поверхности тела (п.т.).МАТЕРИАЛ И МЕТОДЫ 125 пациентов с ИТ и ожогами кожи I–II степени до 3% п.т. были распределены на четыре группы: ИТ без ожогов кожи, с ожогами до 1% п.т., до 2% п.т., до 3% п.т.РЕЗУЛЬТАТЫ В группах с ИТ и ожогами кожи до 2% п.т. число наблюдений ОДН, пневмонии и случаев смертельных исходов статистически значимо не отличалось от группы ИТ, а в группе ИТ и ожогами свыше 2% п.т. их было больше.ВЫВОДЫ Ожоги кожи I–II степени свыше 2% п.т. увеличивают частоту развития острой дыхательной недостаточности, пневмонии и случаев смертельных исходов у пациентов с ингаляционной травмой

Association of hypertriglyceridemia with risk factors for cardiovascular and renal complications in individuals with high cardiovascular risk

Aim. To study clinical and functional manifestations of hypertriglyceridemia and its association with risk factors for cardiovascular and renal complications in individuals with high cardiovascular risk.Material and methods. The study included 272 patients (129 men and 143 women; mean age, 53,9±13,7 years) with a high cardiovascular risk, which was stratified using Systematic Coronary Risk Evaluation (SCORE) model by the presence of cardiovascular disease, and/or diabetes, and/or age ≥65 years, and/or blood pressure (BP) >180/110 mm Hg, and/or total cholesterol (TC) level >8,0 mmol/l. All study participants underwent clinical and paraclinical examination. Serum content of triglycerides (TGs) ≥1,7 mmol/L was considered hypertriglyceridemia (HTG). Depending on TG level, the entire sample was divided into 2 following subgroups: subgroup 1 (n=178) — serum triglycerides ≤1,6 mmol/l; subgroup 2 (n=94) — serum triglycerides ≥1,7 mmol/l, i.e. HTG.Results. We revealed significantly more persons with obesity (46,8%) and type 2 diabetes (28,7%) in HTG subgroup. There were 56,3% and 36,1% patients of HTG subgroup with hypertension (HTN) and coronary artery disease (CAD), respectively. A mid-high TG level (from 1,7 to 2,3 mmol/l) in the subgroup of patients with HTG was detected in 38,3% of cases. The serum content of TG from 2,3 to 5,6 mmol/l was detected in 54,2% of patients. TG level ≥5,6 mmol/l was detected in 7,5% of cases. In the subgroup of patients with HTG, high levels of systolic, diastolic and central (aortic) BP, body mass index, phosphorus, creatinine, cystatin C, estimated glomerular filtration rate (eGFR), and carotid intima-media thickness (IMT) were detected significantly more common. In the general sample, a significant direct relationship between TG concentration and cystatin C (r=0,168) and an inverse (negative) relationship with eGFR (r=-0,220) was obtained.Conclusion. Elevated serum TG levels are often observed in individuals with obesity, type 2 diabetes, hypertension and CAD. Patients with HTG had a pronounced cardiovascular and renal risk, including a significant increase in BP and carotid IMT, high levels of total cholesterol, low-density lipoprotein cholesterol, phosphorus, creatinine, cystatin C, and a decrease in eGFR. HTG was associated with an increase in serum cystatin C and a deterioration in renal nitrogen excretion

MULTIFACTORIAL ASSESSMENT OF POSTMORTEM LUNG DONOR

The appropriate evaluation and the development of special measures to protect donor lungs are important factors for successful lung transplantation. Aim. To develop and determine the effectiveness of the protocol of morpho- functional assessment of potential lung donor. Methods and results. During the period from May, 2011 to May, 2012, 37 donors with diagnoses of brain death were surveyed. 5 bilateral lung transplantations were performed only in 2 cases donors have been evaluated as «ideal». In the majority of recipients early postoperative period was evaluated as satisfactory. Conclusion. Designed multivariate algorithm of donor with brain death assess- ment, effectively implemented through the selection of donors for lung transplantation with satisfactory results in the early postoperative period. However, compliance with ideal criteria will not allow to effectively provide care for patients with terminal lung disease under conditions of continuous growth of «waiting list»