Properties and thermo-oxidative stability of the dewaxed residual product of the vacuum gas oil hydrocracking process

The article describes the possibilities of using remote monitoring of an intelligent network. The architecture for intelligent monitoring systems in the power industry is considered. The equipment for remote monitoring is described

Properties and thermo-oxidative stability of the dewaxed residual product of the vacuum gas oil hydrocracking process

The article describes the possibilities of using remote monitoring of an intelligent network. The architecture for intelligent monitoring systems in the power industry is considered. The equipment for remote monitoring is described

Statistics of Neutron Stars at the Stage of Supersonic Propeller

We analyze the statistical distribution of neutron stars at the stage of a supersonic propeller. An important point of our analysis is allowance for the evolution of the angle of inclination of the magnetic axis to the spin axis of the neutron star for the boundary of the transition to the supersonic propeller stage for two models: the model with hindered particle escape from the stellar surface and the model with free particle escape. As a result, we have shown that a consistent allowance for the evolution of the inclination angle in the region of extinct radio pulsars for the two models leads to an increase in the total number of neutron stars at the supersonic propeller stage. This increase stems from he fact that when allowing for the evolution of the inclination angle $\chi$ for neutron stars in the region of extinct radio pulsars and, hence, for the boundary of the transition to the propeller stage, this transition is possible at shorter spin periods (P~5-10 s) than assumed in the standard model.Comment: 15 pages, 6 figures; scale corrected for figures 3-

Ways to increase patient compliance in the drugs preferential provision

Compliance of patients in the drugs preferential provision is considered as the most important component of effectiveness and safety pharmacotherapy.Aim. Based on the study of patient compliance in the drugs preferential provision program to develop recommendations and proposals to improve adherence to treatment.Materials and methods. A sociological survey was conducted at 115 patients suffering from chronic diseases in four polyclinics in Vladivostok in 2019. All patients were treated under the «Program of Providing Certain Categories of Citizens with Necessary Drugs». The study used descriptive statistics methods using the Microsoft Office program.Results. The highest level of adherence was noted in the indicators «compliance with the recommendations of the attending physician for taking medicines» — 78.3 % and «absence of a pass in taking medicines» — 76.5 %. The greatest compliance to drugs treatment (< 50 %) on the majority of indicators of questioning is registered at patients with diagnoses: «diabetes mellitus», «bronchial asthma» and «malignant neoplasms», and also at co-morbid patients. The lowest adherence to pharmacotherapy (> 50 %) was in groups of patients with hypertension and chronic renal failure. Compliance in the field of non-drugs treatment is not sufficient.Conclusion. The sociological survey showed that adherence to medication and non-medication treatment is insufficient. To improve the compliance it is recommended the introduction of programs of patient education with use of modern interactive educational technologies

Efficacy and safety of various brimonidine formulations in the treatment of glaucoma and ocular hypertension

Purpose. To present data on the mechanism of action, efficacy, and side effects of various brimonidine dosage forms in the treatment of glaucoma and ocular hypertension.Material and methods. To perform the review, literature sources were searched through the PubMed and Scopus databases up to and including 2021, using the keywords «brimonidine», «efficacy», «safety», «glaucoma medication». A total of 36 articles related to the topic of the review were selected. The beginning of publications on this topic dates back to 1995.Results. Brimonidine, an alpha2-adrenoceptor agonist, effectively reduces intraocular pressure and can be used as monotherapy, adjuvant and replacement therapy. The effectiveness of brimonidine is similar to that of timolol and prevails over betaxolol but inferior to prostaglandin analogues. The new drug formulation brimonidine-purite 0.15% has a more favorable safety and tolerability profile than the original brimonidine 0.2% while maintaining similar efficacy. However, most patients require two or more hypotensive medications to maintain target IOP. In this context, brimonidine is one of the most appropriate drugs because of its pr oven efficacy when combined with other classes of hypotensive drugs.Conclusion. Brimonidine can be used as monotherapy for glaucoma and ophthalmic hypertension. Experimental and clinical studies have shown a potential neuroprotective effect of brimonidine, which is associated with a direct effect on retinal cells, regardless of the effect of the drug on intraocular pressure

Possibilities of Detecting Pre-clinical Forms of Atherosclerosis During Periodic Preventive Inspections in Organized Collectives at Workers of Machine Building Enterprises

Aim. To study the structural and functional features of the carotid and femoral arteries using ultrasound duplex scanning of them in patients with hypertension undergoing periodic preventive medical examination.Material and methods. Periodic preventive examination was carried out for 2431 employees (1311 men and 1120 women) aged 20-65 years using a specially developed questionnaire, blood pressure measurement, anthropometry, total cholesterol test. Hypertensive men were assessed for preclinical manifestations of atherosclerosis by ultrasound duplex scanning of the carotid and femoral arteries.Results. Hypertensive men (BP ≥140/90 mmHg and/or taking antihypertensive drugs; n=176, mean age 43.5 years) were included in the study. An increase in the thickness of the intima-media complex in the carotid arteries was found in 22.2% (n=38) people, in the femoral arteries – in 34.1% (n=60) people, in both basins – in 16.5% (n= 29) man. Atherosclerotic plaques in the carotid arteries were found in 40.3% of people (n=71), and in the femoral arteries – in 34.7% (n=61) of people, in both pools – in 23.9% (n=42) of men.Conclusion. Ultrasound diagnostic using modern ultrasound scanners is a highly informative method for non-invasive diagnosis of atherosclerosis in the arteries of the carotid and femoral basins in employees of a large industrial enterprise with arterial hypertension in the conditions of the medical and sanitary department. Carrying out these diagnostic approaches is advisable when organizing periodic medical examinations in order to improve primary prevention, as well as to prevent the aggravation of the identified pathological process, reduce complications, improve quality and increase life expectancy

On the Question of Pedagogical Digital Competence

Educational institutions develop professional training programs for teachers so they could bring technology into the classroom and take the quality of education to a new level. However, despite the measures being adopted, a number of researchers report unsatisfying results. One of the root causes of this situation seems to be the absence of clear understanding of what the notions of digital competence and pedagogical digital competence are supposed to include. This problem is tightly connected with the problem of creating a framework for the development of digital skills of an instructor. On one hand, there is a demand for universal models that would include a wide range of pedagogical digital skills. There is a demand for universal models, which would include the widest possible range of digital competences of a teacher. Among them there are such existing frameworks as DigiCompEdu, ICT CFT, TETCs, which cover numerous aspects of instructors’ work. Meanwhile, there is the lack of models that would structurize the professional practice of a teacher at the micro level of using a digital instrument. There is a necessity for the framework comprising a limited set of primary basic skills which would be universal enough to be applicable to operating any kind of technology. In the article, we propose a version of this type of a framework