A comprehensive review on electrospinning design, parameters and potential use of electrospun nanofibers in regenerative endodontics

Electrospinning is a versatile technique that has gathered interest due to its ability to fabricate nano and microscale fibres with unique properties of high surface area and fibrous porosity. This technique has been widely used in the late 20th (1990) and early 21st (2000) centuries. Since the beginning of its use, significant improvements have been made in the design, materials used, and fibres produced. The electrospinning technique is used to fabricate a material with therapeutic properties as it allows the researchers to incorporate various anti-microbial agents to different polymers without altering the chemical characteristicsof polymers.The production of nanofibres through electrospinning is affected by many operating parameters. It is, therefore, essential to know various parameters and processes that aid in fabricating the desired fibre assemblies. The nanofibres remain an essential division of biomaterials due to a wide range of biomedicalapplications. Nanofibres have unique properties such as protein absorption, binding sites to cell receptors, can provide maximum volume fraction by controlling fibres\u27 alignment and orientation hence improving the material properties like surface morphology, porosity, and geometry.Recent trends in endodontics, encourage regenerative therapy for the treatment of necrotic immature permanent teeth for root development and maturation. In this context, efficient disinfection of the root canal system is a crucial step. Existing chemical irrigating solutions (for eg., NaOCl) and antibiotic pastes (for eg., Triple antibiotic paste) usage at higher doses showed toxic results on the pulpal stem cells. Therefore, it was found to be beneficial to use a nanofibre-based intracanal drug delivery construct to release antibiotics at lower, yet anti-microbially effective concentrations.This review aims to discuss the basic concepts of electrospinning and its potential application in regenerative endodontics along with various parameters, which affect the fibre morphology and properties of produced nanofibres

Fallopian tube as a cause of intestinal obstruction: a rare case report with review of literature

Adhesive Intestinal obstruction is the most common cause of intestinal obstruction in post-operative period. Diagnosis is based on history, clinical examination, plain X-ray abdomen. Authors here report an interesting case of intestinal obstruction after surgery for chronic calcific pancreatitis with pancreatic duct stone with intractable pain. In post-operative period patient developed features of intestinal obstruction, patient was planned for re- exploration and it was found that band was formed by left fallopian tube with transition point at terminal ileum and treated successfully with left Salpingectomy. Very few cases of fallopian tube as cause of intestinal obstruction have been reported in literature and it should be considered as one of the cause of intestinal obstruction in females presenting with acute abdomen

Abstracts of National Conference on Biological, Biochemical, Biomedical, Bioenergy, and Environmental Biotechnology

This book contains the abstracts of the papers presented at the National Conference on Biological, Biochemical, Biomedical, Bioenergy, and Environmental Biotechnology (NCB4EBT-2021) Organized by the Department of Biotechnology, National Institute of Technology Warangal, India held on 29–30 January 2021. This conference is the first of its kind organized by NIT-W which covered an array of interesting topics in biotechnology. This makes it a bit special as it brings together researchers from different disciplines of biotechnology, which in turn will also open new research and cooperation fields for them. Conference Title: National Conference on Biological, Biochemical, Biomedical, Bioenergy, and Environmental BiotechnologyConference Acronym: NCB4EBT-2021Conference Date: 29–30 January 2021Conference Location: Online (Virtual Mode)Conference Organizer: Department of Biotechnology, National Institute of Technology Warangal, Indi