232 research outputs found
Improved Rsa Algorithm for Data Security against DDoS Attack in a Cloud-based Intrusion Detection System
Today, more and more industries are using cloud computing for some integration operations, but ensuring the security of user data and system resources remains a challenge. This article proposes a method to identify and mitigate unwanted packets and traffic, especially duplicate packets, in cloud computing environments. The method includes creating an Intrusion Search and Detection (IF-AD) system to securely maintain user information and allocate secondary memory. To detect unwanted traffic, this method compares the size of the downloaded file with the original file, identifying any differences as potential DDoS. RSA encryption mechanism is used for subsequent file transfers for added security. The proposed approach aims to enhance the security posture of cloud-based systems by detecting and preventing unauthorized access and file modification
Simulation studies of PV fed Line Frequency Commutated 5-Level Inverter
Power electronic converters are essential for harnessing the abundantly available solar energy. Power from the photovoltaic array can be fed to the ac load or utility grid through inverter which is capable of producing an ac voltage with less harmonics. A multilevel inverter is generally employed for this purpose at the cost of extra switches and control complexity. In this paper, a system is proposed to obtain a multilevel output by introducing a simple auxiliary circuit between the photovoltaic array and the line frequency commutated inverter. Simulation studies of the proposed system have been carried out using MATLAB/Simulink software and the results are presented in this paper
Pufferfish Lagocephalus inermis - an emerging fishery along Mangalore coast of Karnataka
L agocephalus inermis (Temminck & Schlegel,
1850) commonly known as smooth blaasop,
belongs to the family Tetraodontidae and order
Tetraodontiformes. This fish was considered as a
menace by fishermen during the previous year (2006)
as it caused damage to other species landed and
the net
Standardization on purification process of Cherangkottai (Semecarpus anacardium-Dried Fruit)
The study drug Cherangkottai(Semecarpus anacardium -dried fruit) was purchased from two different places, one in Country drug shop,Chennai and another in country drug shop,
Kanyakumari, and one more sample was obtained from hilly area of Thakalay at Kanyakumari District. Among these three Cherangkottai( Semecarpus anacardium- dried fruit) collected from the hilly area of Thakalay was selected to standardize the before and after purification.
The study drug Cherangkottai(Semecarpus anacardium) was identified and authenticated by based on pharmacognosy report. The pharmacognosy report suggest the test sample was
Cherangkottai( Semecarpus anacardium - dried fruit). And the other herbs used for purification process were identified and authenticated by based on organoleptic, macroscopic & microscopic examination. The study sample Cherangkottai(Semecarpus anacardium - dried fruit) was
purified as per Siddha literature, Gunapadam ,Part I,Mooligai vaguppu, Vaithya Rathinam.K.S.Murugesa Mudhalaiyar.
Physicochemical properties of sample I and sample II was analysed, moisture content was reduced after purification than before purification. Slightly changed in pH after purification.
Thus revealed the purity, higher stability, long term storage and state of better absorption of purified Cherangkottai(Semecarpus anacardium dried fruit)- (sample II). The phytochemical analysis shows the presence of phenols, flavonoids, quinones, glycosides, aminoacids,
carbohydrates and proteins.
The microbial load was analyzed before and after purification of Cherangkottai (Semecarpus anacardium -dried fruit) -sample I and sample II. Total bacterial count and total fungal count, E.coli, Salmonella, Staphylococcus were tested to ensure the safety of the drug in both samples.
Heavy metal analysis was done by AAS method and absence of arsenic, mercury, cadmium, lead was noted in both samples. Pesticides residue and aflatoxin level were quantitatively measured in both the sample I and sample II, the result indicated the absence of them.
The presence of elemental analysis was done by ICPOES method and the results shows the presence of calcium, copper, magnesium, manganese, sulphur, sodium, selenium,
molybdenum& phosphorus.
HPTLC analysis was carried out in sample I and sample II. In sample I, 6 major bands at 254 nm and 10 major bands at 366 nm and 5 clear bands in VS reagent. In sample II, 6 major
bands at 254 nm and 9 major bands at 366 nm and 6 clear bands in VS reagent.
The HPTLC result shows predominantly five major components at 254 nm in sample I and 4 major components at 254 nm in sample II. Again the HPTLC result shows predominantly
4 major component at 366 nm(absorbent mode) in sample I and 5 major component at 366nm(absorbent mode) in sample II and in flourescence mode, it showed 4 major component in sample I and 5 major component in sample II HPTLC analysis was carried out in sample I and sample II. The TLC profile showed 6 major bands under UV 254 nm. 10 major band in UV 366 nm and 5 clear bands after derivatizations in sample II.
HPTLC fingerprinting pattern at 254 of sample II have 10 spots at Rf values, 0.06, 0.11, 0.31, 0.38, 0.49, 059, 0.77, 0.86, 0.and0.96. Rf indicating the occurrence of alteast ten different component in alcoholic extract. It is also clear that out of ten components the component with Rf value o.59,0.96,0.31,0.11 were found to be more predominant as the % area is more with 29.24%,20.75%,12.58%,11.04% respectively .The other peaks were found to be minor as the % area for the peaks was less.
The TLC profile showed 6 major bands under UV 254 nm. 9 major bands UV 366nm and 6 clear bands after derivatizations in sample I.
The HPTLC finger printing pattern at 254 of sample I have 11 spots at Rf value 0.03, 0.07, 0.09,0.13, 0.33, 0.47,0.52, 0.62, 0.80, 0.92and 0.96 Rf values indicates the occurrence of atleast 11 different in alcoholic extract. it is also clear that out of 11 components the components
with RF values 0.62, 0.33, 0.96, 0.922, were found to be more predominant as the percentage area is more with 26.95, 20.97, 20.06, 11.54% respectively. The other peaks were found to be minor as the % area for the peaks were less.
The HPTLC fingerprint pattern at 366 nm ( absorbent mode) of sample I have 5 spots at Rf value 0.10, 0.45, 0.52, 0.80 and 0.94. Rf value indicates the occurrence of atleast 5 different in alcoholic extract. It is also clear that out of 5 components the component with Rf value.0.45,0.52,0.94,0.80,0.10 were found to be more with 29.81, 23.55, 20.90, 13.04, 12.69 respectively. The other peaks were found to be minor as the % area the peaks were less. The HPTLC fingerprinting pattern at 366nm (absorbent mode)of sample II have 6 spots at Rf value
0.09, 0, 18, 0.40, 0.49, 0.77 & 0.93. These Rf values indicates the occurrence of atleast 6 different in
alcoholic extract. It is also clear that out of 6 components the component with Rf value 0.49, 0.40, 0.93, 0.09, 0.77, were found to be more predominant as the %area is more with
24.50, 23.84, 16.96, 16.21 & 12.75respectively. The other peaks were found to be minor as the % area for the peaks were less.
The HPTLC finger printing pattern at 366 nm (flouresence mode) of the sample I have 6 spots at Rf value 0.07, 0.46,0.50, 0.65, 0.92, 0.97. Rf values indicatses the occurrence of atleast 6 different in alcoholic extract. It is also clear that out of 6 components the component with Rf
value 0.46, 0.92, 0.65, & 0.97, were found to be more predominant as the %area is more with 27.19, 25.17, 18.55 & 18.04 respectively. The other peaks were found to be minor as the %area for the peaks were less.
The HPTLC finger printing pattern at 366nm (flouresence model) of sample II have 10 spots at Rf value 0.10, 0.06,0.15, 0.38, 0.48, 0.63, 0.68, 0.71, 0.91, 0.98 Rf indicates the occurrence of atleast 10 different in alcoholic extract. It is also clear that out of 10 component the component with Rf value 0.01, 0.91, 0.63, 0.48, 0.98 were found to be more predominant as the % area is
more with 27.65%, 14.19%, 14.03%, 13.56%, 12.86% respectively. The other peaks were found to be minor as the % area for the peaks were less.
The HPTLC finger print studies can be used as a diagnostics tool to determine the quality and purity of the drug.
CONCLUSION:
Based on various analysis before and after purification of Cherangkottai (Semecarpus anacardium тАУdried fruit) concludes that, purification process of Cherangkottai is important
before pharmaceutical preparations.
The physicochemical results of purified Cherangkottai confirmed purity and stability of drug.
The moisture content of purified Cherangkottai is 4.94%. It denotes shelf life of the drug increase after purification as per standard Siddha literature.
PH of purified Cherangkottai is 5.95.It denotes better absorption of the drug through oral administration.
Heavy metals and Microbial loads are absent in both samples which ensure the safety of the Cherangkottai.
Pesticides and Aflatoxins are absent before and after purification of Cherangkottai which ensure its safety.
Biologically active trace elements like calcium, magnesium, manganese,selenium, copper, molybdenum, sulphur and phosphorus are increase after purification of Cherangkottai.
In HPTLC analysis also shows the concentrations of various components are vary before and after purification of Cherangkottai.
Thus the present study of purification of Cherangkottai reveals, impurities are removed and the quality of the drug is improved. Therefore when a drug is purified and used as medicine will increase the potency and efficacy of the drug.
The achieved results of Pharmacognosy, Physicochemical, Preliminary phytochemical tests, Heavymetal analysis, Microbial load, Pesticide residues, Aflatoxins, TLC profiling and HPTLC fingerprint profiling will be useful as tool for authentication, standardization profile and
quality control assessment of the Cherangkottai (Seme carpus anacardium-dried fruit)
Efficacy of spatial study on catch and effort from fishing vessels for strengthening fisheries management
Ever since marine fishery operations were extended beyond territorial waters of respective states, the need was felt for incorporating spatial component of fishing effort and catch for formulating marine fishery policies. The present study is an attempt of spatio-temporal analysis of changing scenario of fishing operations in GIS platform with catch and effort data collected from fishermen, to highlight the need for the change in approach in fisheries management and also for updating the information of fishing along the Indian coast. Marine fishing operations by commercial fishing vessels operated from different states has extended up to 200 m depth since 2000 and duration of fishing, especially trawling extended from single day to 8-13 days per voyage. Present findings were drawn from the analysis of 1,217 days of trawling operations during 2007-2013 by a sampling trawler supplemented by additional fishing operational data support from a group of commercial trawlers. Study reveals that there is an organised and confidential maintenance of log sheets in most of the progressive trawler operators and the information available in spatial platform can be utilized for better fisheries management with fishermenтАЩs participation. Spatial analysis of fish catch from the sampling trawler operated from Mangalore showed that more than 70% of the fish landed in Mangalore was brought from the area beyond the territorial waters of Karnataka signifying that majority of fish catch landing to the state is from waters beyond their jurisdiction. Even though the fishery beyond territorial waters of all maritime states is s governed by Government of India, so far, there is no comprehensive management plans regarding fishing operations beyond territorial waters of the states. The study further reveals that fishing grounds beyond territorial waters of each state are being intensively fished without any fishing regulations and there were many conflicts being reported from these waters concerning the fishing rights of different sectors and different states. In the light of the findings from the study on fishing operations and fishery, an action plan to regulate the fishery off the territorial waters of each state is felt essential. тАЬRegional fisheries committeesтАЭ with members constituting the officials from neighbouring states sharing same resources with the aegis of Central Government is recommended as a viable option to take care of the
management of the fishery within the Indian EEZ
Prospective Randomized Controlled study comparing Intrathecal Magnesium Sulphate Versus Fentanyl Citrate as an adjuvant to 0.5% Bupivacaine heavy in spinal Anaesthesia for Infraumbilical Surgeries
AIM OF THE STUDY:
To evaluate the duration of analgesia of bupivacaine with fentanyl versus bupivacaine during with magnesium sulphate during spinal anaesthesia for infraumbilical surgeries .
MATERIALS AND METHODS:
The study was carried out in department of anaesthesiology, ESICMC PGIMSR, Chennai. A total of 70 patients included in the study during June 2016 to May 2017. These patients were randomly divided into two groups.
METHADOLOGY:
Group A received 3 ml of 0.5 % hyperbaric bupivacaine and 0.5 ml of 25 mcg of fentanyl. Group B received 3 ml of 0.5 % hyperbaric bupivacaine and 100 mg of magnesium sulphate. They onset of sensory and motor blockade, duration of sensory and motor blockade, duration of analgesia and incidence of side effects such as pruritus, sedation, hypotension and bradycardia.
RESULTS:
Addition of magnesium sulphate delayed the onset of sensory and motor blockade without prolonging the duration of sensory and motor blockade as fentanyl. Duration of analgesia was comparable in both groups. Incidence of side effects was more in fentanyl group.
CONCLUSION:
Thus, we conclude that addition of 100 mg magnesium sulphate to 0.5 % hyperbaric bupivacaine intrathecally, delayed the onset of sensory and motor blockade, when compared to addition of fentanyl. Further, addition of magnesium sulphate at dose of 100 mg prolongs the duration of analgesia to the same extent as fentanyl with stable hemodynamic profile and lesser side effects when compared to fentanyl
A case report on steroid induced diabetes mellitus
A steroid is a biologically active organic compound having immunosuppressive action in living organism. Different classification of steroids is available in pharmaceutical industry. Steroids are mostly suggested by clinician to the patients for the reduction of inflammation caused by immune system. Steroid can cause elevation of patient blood sugar level. Those who take steroids for a longer period of time are more susceptible to develop diabetes mellitus. The most commonly used steroids are prednisone and cortisone. These drugs promote glucose production in liver and reduce the sensitivity of cells to insulin. In this case report a 45 year old women suffering from nephrotic syndrome was advised to take Inj. Methyl prednisolone . The administration of this drug leads to a rise in her blood sugar level. It is typical case of steroid induced diabetes mellitus
SYNTHESIS OF MESOPOROUS SILICA NANOPARTICLES AND DRUG LOADING FOR GRAM POSITIVE AND GRAM NEGATIVE BACTERIA
Objective: To synthesize mesoporous silica nanoparticles using the sol-gel method and to determine the antibacterial activity of mesoporous silica nanoparticles and tetracycline loaded mesoporous silica nanoparticles.Methods: In the synthetic procedure, the surfactant Cetyl Trimethyl Ammonium Bromide (CTAB) is initially dissolved in basic aqueous solution, and the mixture is vigorously stirred. Tetra Ethyl Ortho Silicate (TEOS) is added, and the solution is kept stirring for 6 h. After the reaction is complete, the as-synthesized product is filtered and washed with deionized water. The antibacterial was tested using disc diffusion method and minimum bactericidal concentration (MBC).Results: The synthesized mesoporous silica nanoparticles were characterized by using Scanning Electron Microscope (SEM) micrographs showed spherical particles with an average size of 350 nm. The powder X-Ray Diffraction (XRD) analysis of the material further confirmed the crystallinity of the mesopores as evidenced by the diffraction pattern of an intense peak at ├О┬╕=24├В┬║. Fourier Transform Infra Red Spectroscopy (FTIR) indicated the involvement of carboxyl, amine and hydroxyl groups in the synthetic process. The result shows the inhibitory growth zone of 20 mm and 18 mm for tetracycline loaded mesoporous silica nanoparticles against Escherichia coli and Staphylococcus aureus respectively.Conclusion: To summarize, it has been experimentally demonstrated that mesoporous silica nanoparticle and tetracycline loaded mesoporous silica nanoparticles show very good antimicrobial behavior against the gram-positive (Staphylococcus aureus) and gram negative (Escherichia coli) bacteria.Keywords: Mesoporous silica nanoparticles, Sol-gel method, Drug loading, Antibacterial activit
Case of leucism in the spadenose shark, Scoliodon laticaudus (M├╝ller and Henle, 1838) from Mangalore, Karnataka
The present paper reports the first case of leucism in the spadenose shark, Scoliodon laticaudus from India. This report is based on the study of a single specimen of S. laticaudus caught by a commercial trawler off Mangalore coast. Photographs were taken and measurements recorded using vernier calipers. Partial reduction in pigmentation and no other morphometric differences were seen between the specimen studied and other normal spadenose sharks. Conclusion of leucism in the specimen was done based on the partial lack of integumentary pigments and normal eye colour
Adoption of sustainable capture based aquaculture practices by traditional fishermen of Karnataka
Capture Based Aquaculture (CBA) has emerged as the optimal solution to meet India's ever growing demand for protein food
security, besides providing additional income to rural fishermen during the lean seasons. The following study documents the
adoption of sustainable CBA in traditional farming systems with minimum inputs. The fish farmer being the end user in the
technology adoption process, an empirical evaluation of the concept of sustainability is important in reducing the production
costs, in harnessing environmental benefits and ensuring stable fish production. The reliability of Farmer Sustainability
Index (FSI) to measure the adoption of sustainable practices in capture based aquaculture was measured using Cronbachs
Coefficient of Alpha which worked out to 0.97, indicating a high index of reliability of the method used. The FSI constructed
was administered to 40 traditional fishermen adopting CBA at Uppunda village of Kundapura taluk of coastal Karnataka.
The overall mean FSI index for all the six practices from cage fabrication to harvest was 77.95, indicating a relatively high
value of Farmer Sustainability Index for adoption of CBA practices
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