23 research outputs found

    Recent Trends in Computing

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    ABSTRACT Huge amount of video data is being generated every day, with enormous growth of security and surveillance system. It is immensely challengeable for researcher to search and retrieve accurate human face of interest from video with utmost speed. The proposed work is stimulated from the same concern. It would be the future demand for searching, browsing, and retrieving human face of interest from video database for several applications. This paper proposes the novel algorithm for human face retrieval from video database based on holistic approach. The Viola and Jones frontal face detector detect the face region. The next stage is face extraction which have input for grouping individual faces. The individual group of faces has converted into single normalized mean face using PCA. The final face group contains single face for each person occurred in video. After the pre-processing of normalized faces, recognition is performed on the basis of query face image

    Analysis of Information Visualization Techniques for Abstract data on Mobile Devices

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    To perform visualization on mobile devices different types of data may use like text, picture, maps, physical objects, abstract data etc. According to data visualization is categorized in two areas of visualization that is, scientific visualization and information visualization. Scientific visualization refers to some specific type of data like physical data and it is used for computer modeling and simulation. Information visualization refers to abstract data and used in business and finance, administration, digital media and other abstract concepts. The physical and abstract data is only one classification but there are others classification like static and dynamic data, structured and unstructured data, or hierarchical and non-hierarchical data classification. This paper is focus on information visualization of abstract data on mobile devices

    Structure, activity, and inhibition of the carboxyltransferase beta-Subunit of acetyl coenzyme a carboxylase (AccD6) from mycobacterium tuberculosis

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    In Mycobacterium tuberculosis, the carboxylation of acetyl coenzyme A (acetyl-CoA) to produce malonyl-CoA, a building block in long-chain fatty acid biosynthesis, is catalyzed by two enzymes working sequentially: a biotin carboxylase (AccA) and a carboxyltransferase (AccD). While the exact roles of the three different biotin carboxylases (AccA1 to -3) and the six carboxyltransferases (AccD1 to -6) in M. tuberculosis are still not clear, AccD6 in complex with AccA3 can synthesize malonyl-CoA from acetyl-CoA. A series of 10 herbicides that target plant acetyl-CoA carboxylases (ACC) were tested for inhibition of AccD6 and for whole-cell activity against M. tuberculosis. From the tested herbicides, haloxyfop, an arylophenoxypropionate, showed in vitro inhibition of M. tuberculosis AccD6, with a 50% inhibitory concentration (IC50) of 21.4 ± 1 ÎŒM. Here, we report the crystal structures of M. tuberculosis AccD6 in the apo form (3.0 Å) and in complex with haloxyfop-R (2.3 Å). The structure of M. tuberculosis AccD6 in complex with haloxyfop-R shows two molecules of the inhibitor bound on each AccD6 subunit. These results indicate the potential for developing novel therapeutics for tuberculosis based on herbicides with low human toxicity.Manchi C. M. Reddy, Ardala Breda, John B. Bruning,* Mukul Sherekar, Spandana Valluru, Cory Thurman, Hannah Ehrenfeld, James C. Sacchettin
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