Ketoprofen induced photoallergic reaction

Photoallergic reactions are hypersensitivity reactions which occur when ultraviolet radiation interacts with ingredients in drugs or other products applied directly to the skin. The body’s immune system recognizes the changes caused by ultraviolet radiation as a foreign threat, so it produces antibodies and causes inflammation of the skin in the exposed areas. Common photoallergic drugs and ingredients are included in some sunscreens, aftershave lotions, antimicrobials (especially sulfonamides), non-steroidal anti-inflammatory drugs (NSAIDs), chemotherapy drugs and fragrances

Ketoprofen induced photoallergic reaction

Photoallergic reactions are hypersensitivity reactions which occur when ultraviolet radiation interacts with ingredients in drugs or other products applied directly to the skin. The body’s immune system recognizes the changes caused by ultraviolet radiation as a foreign threat, so it produces antibodies and causes inflammation of the skin in the exposed areas. Common photoallergic drugs and ingredients are included in some sunscreens, aftershave lotions, antimicrobials (especially sulfonamides), non-steroidal anti-inflammatory drugs (NSAIDs), chemotherapy drugs and fragrances

Five years milk quality in Vojvodina received in Novi Sad dairy with special reference to SNF

Proučavanje i praćenje kvalitete zbirnog mlijeka s otkupnih terena pojedinačno po mljekarama, čini stalan i sistematski rad stručne i naučne službe u mljekarstvu. Genetski i paragenetski faktori u govedarstvu se neprestano mijenjaju i poboljšavaju, pa se mlijeko vremenski i prostorno u kvaliteti mijenja.Five years average quality of milk was studied by testing butter fat content, specific gravity and solids-not-fat, from purchasing area of Novi Sad Dairy, situated in a lowland area. The quality of the purchased milk was high. Five years average of butter fat in the bulk milk amounted 3.69 per cent. Milk from society owned farms had 3.81 per cent and from individual holding 3.6 per cent of fat, respectively

Factors affecting elimination of polycyclic aromatic hydrocarbons from traditional smoked common carp meat

Smoking techniques have been progressively improved and different procedures have been developed in different regions for treating fish. In these times, the technology is mainly used for enrichment of fish with specific taste and odour, to extend the shelf-life of these perishable products and appearance required widely on the market. A lot of chemical contaminants such as polycyclic aromatic hydrocarbons (PAHs) are formed during the combustion of fuel in the smoking process. PAHs are a group of compounds that have been the subject of great concern in the recent years due to their toxic, mutagenic and/or carcinogenic potentials to humans. These fact can have a significant impact on the acceptance of these products by consumers. In this review article, the objective is to describe factors affecting elimination of polycyclic aromatic hydrocarbons from traditional smoked common carp meat

Identification and Perceived Value of Ecosystem Services of Urban Green Areas. Case Study: Kamenički Park in Novi Sad, Serbia

Urban parks, as one of the most significant urban green areas (UGA), bring many direct or indirect benefits, including but not limited to ecosystem services (ES) (Mexia et al. 2018). These services are often generalized, unquantified and poorly supported by empirical evidence and their negative consequences – disservices are rarely mentioned (Roman et al., 2021; Pataki et al., 2011). In order to improve planning, design and management of UGA that can increase their environmental benefits (Xie et al. 2019), better understanding and additional field research of ES and disservices is required. As a result of a survey of employees of the Institute for Nature Conservation of Vojvodina Province that manages the park and on-site users, this study represents a research of the perceived value of generated ES on the example of Kamenički park in Novi Sad, as there are no studies on the actual value of those ES. After identifying major ES, the employees and users evaluated them by their perception on a scale of 1 – the ES is well provided, 2 – service is provided but can be enhanced and 3 – the service is not provided, but has potential. Employees mainly emphasized regulation and supporting services (regulation of air quality, noise reduction, wind protection, maintaining biodiversity), but also cultural services (educational role, recreation and enjoying nature, spiritual peace and prosperity). Users opted mainly for cultural services (recreation and enjoying nature and inspiration for culture, art and design), but also for supporting services like maintaining biodiversity. The specific location, valuable natural and cultural-historical characteristics of Kamenički park contribute to the provision of numerous ES, but also offer the opportunity to develop additional ones that are currently not represented or are not sufficiently provided. The opinions and needs of stakeholders and users regarding ES can be a guideline in planning in accordance with the ES, which is a step to sustainable cities. Quantifying the degree to which various ES are related to plant diversity and structure would provide evidence of the ability to manipulate designed ecosystems to maximize the benefits they provide to urban landscapes (Nighswander et al. 2021)

Application of Quality of Experience in Networked Services: Review, Trend & Perspectives

Full text embargoed until 17.10.2019 (publisher's embargo period, 12 months

Improved National Croatian Diagnostic and Therapeutic Guidelines for Premalignant Lesions of the Uterine Cervix with Some Cost-Benefit Aspects

The national Croatian improved diagnostic and therapeutic guidelines for premalignant lesions of the uterine cervix are presented: for atypical squamous cells of undetermined significance (ASCUS), for cervical intraepithelial neoplasia (CIN I, CIN II, CIN III) and for microcarcinoma (FIGO grade Ia1). Separately are presented the guidelines for abnormal glandular epithelium: atypical glandular cells of undetermined significance (AGCUS) and cervical glandular intraepithelial neoplasia (CGIN). The guidelines are created according to the guidelines of the FIGO. Improved diagnostic and therapeutic guidelines was presented and accepted at the Symposium of the Croatian Society for Colposcopy and Cervical Pathology and of the Croatian Society of Gynecologists and Obstetricians of the Croatian Medical Association, held on November, 25th 2000. There are presented the chief differences and the some cost-benefit aspects between the guideline s before and the new one

Application of liquid chromatography with diode-array detector for determination of acetamiprid and 6-chloronicotinic acid residues in sweet cherry samples

Acetamiprid is a broad-spectrum neonicotinoids insecticide used on a wide range crops, especially fruits. Besides its positive effects, acetamiprid also has been posing various health risks to consumers. Due to the growing use of insecticides from the family of neonicotinoids, their increased presence in the environment is evident. For this reason, the concentration of acetamiprid residues, including its metabolite 6-chloronicotinic acid, in agricultural products should be monitored. A rapid and simple method for the confirmation, simultaneous analysis and quantification of acetamiprid and 6-chloronicotinic acid as intermediate of acetamiprid decomposition in sweet cherry samples has been developed. This residue analysis method is based on the reversed phase separation on C18 column with gradient elution. Analytes’ determination and quantification were performed by high performance _ liquid chromatography (HPLC) with photodiodes detection and chromatograms were extracted at 230nm. Extraction efficiency experiments demonstrated the ability of this method to extract neonicotinoids from sweet cherry samples. These insecticides were extracted with mixture acetonitril/0.1N ammonium-chloride (8/2, v/v). The extract was filtered through layer of celit and evaporated, the residue dissolved with acetone and then analyzed by liquid chromatography. The standard addition method was used for acetamiprid and 6-chloronicotinic acid determination in order to eliminate the matrix effect. Sweet cherry samples spiked with the concentration levels of 0.5mg/kg and 1mg/kg was used to ensure method accuracy (recovery) and data precision. The repeatability of the retention times and peak areas were checked by injecting the standard mixture of acetamiprid and 6-chloronicotinic acid solution five times. Average recoveries of acetamiprid and 6-chlornicotinic acid from sweet cherry samples were in the range of 95-101% and 73-83%, respectively with the associated relative standard deviations (RSDs) < 5%. Limit of detection (LOD) for the analyzed acetamiprid and 6-chloronicotinic acid was estimated from fortified samples. The limit of quantification (LOQ) was 10 and 30u9/kg for acetamiprid and 6-chloronicotinic acid, respectively. Thus, it can be concluded that the developed HPLC-DAD method represents a useful tool for a sensitive and rapid determination of acetamiprid and 6-chloronicotinic acid. Hence, the method may find further application in the analysis of real sweet cherry samples contaminated with these insecticides at a ppb level

Procena merne neizvesnosti i validacija metode određivanja acetamiprida i 6-hlornikotinske kiseline u uzorcima trešanja

Pojava ostataka pesticida u voću i povrću moguća je i pored poštovanja principa dobre poljoprivredne prakse. Identifikacija prisutnih pesticida i određivanje njihovih količina u ovim matriksima zahteva primenu metoda visoke osetljivosti i selektivnosti. Istraživanje je sprovedeno u cilju iznalaženja optimalnih eksperimentalnih uslova za razdvajanje i određivanje acetamiprida i njegovog metabolita, 6-hlornikotinske kiseline (6-HNK) u uzorcima trešanja, korišćenjem tečne hromatografije sa nizom fotoosetljivin dioda (DAD). Uzorci trešanja su korišćeni da bi se odredila selektivnost, linearnost, tačnost i limit kvantifikacije (LOQ). Tačnost metode je kvantifikovana kroz procenu merne neizvesnosti zasnovanu na podacima validacije metode