61 research outputs found
Comparative Evaluation of the Biochemical Effects of Ketamine plus Ketoprofen and Midazolam in the Premedication of Pigeons
The present study was conducted with the aim of comparing the effects of premedication with ketoprofen and midazolam in birds. A total of 24 male pigeons with an approximate weight of 300 g were divided into four equal groups. The control group (Group I) was injected with ketamine alone. Groups II-IV were injected with ketoprofen alone, ketoprofen+ketamine, and midazolam+ketamine, respectively. The biochemical changes in the four groups were evaluated after intramuscular drug injections at different anesthetic levels. A record of biochemical changes was maintained for each group. Blood samples were taken before and after the administration of the medications in order to measure the levels of serum alkaline phosphatase (ALP), oxaloacetate transaminase (OT), prothrombin time (PT), glucose (GLU), lactate dehydrogenase (LDH), albumin (Alb), total protein (TP), and gamma-glutamyl transferase (GGTF). The results showed significant differences in the mean levels of ALP, OT, PT, GLU, LDH, Alb, and TP after anesthesia, compared to that before anesthesia. Therefore, ketoprofen+ketamine can be used for the induction of anesthesia in birds.The present study was conducted with the aim of comparing the effects of premedication with ketoprofen and midazolam in birds. A total of 24 male pigeons with an approximate weight of 300 g were divided into four equal groups. The control group (Group I) was injected with ketamine alone. Groups II-IV were injected with ketoprofen alone, ketoprofen+ketamine, and midazolam+ketamine, respectively. The biochemical changes in the four groups were evaluated after intramuscular drug injections at different anesthetic levels. A record of biochemical changes was maintained for each group. Blood samples were taken before and after the administration of the medications in order to measure the levels of serum alkaline phosphatase (ALP), oxaloacetate transaminase (OT), prothrombin time (PT), glucose (GLU), lactate dehydrogenase (LDH), albumin (Alb), total protein (TP), and gamma-glutamyl transferase (GGTF). The results showed significant differences in the mean levels of ALP, OT, PT, GLU, LDH, Alb, and TP after anesthesia, compared to that before anesthesia. Therefore, ketoprofen+ketamine can be used for the induction of anesthesia in birds
A stochastic programming approach for chemotherapy appointment scheduling
Chemotherapy appointment scheduling is a challenging problem due to the
uncertainty in pre-medication and infusion durations. In this paper, we
formulate a two-stage stochastic mixed integer programming model for the
chemotherapy appointment scheduling problem under limited availability and
number of nurses and infusion chairs. The objective is to minimize the expected
weighted sum of nurse overtime, chair idle time, and patient waiting time. The
computational burden to solve real-life instances of this problem to optimality
is significantly high, even in the deterministic case. To overcome this burden,
we incorporate valid bounds and symmetry breaking constraints. Progressive
hedging algorithm is implemented in order to solve the improved formulation
heuristically. We enhance the algorithm through a penalty update method, cycle
detection and variable fixing mechanisms, and a linear approximation of the
objective function. Using numerical experiments based on real data from a major
oncology hospital, we compare our solution approach with several scheduling
heuristics from the relevant literature, generate managerial insights related
to the impact of the number of nurses and chairs on appointment schedules, and
estimate the value of stochastic solution to assess the significance of
considering uncertainty
Hydroethanolic Allium sativum extract accelerates excision wound healing: evidence for roles of mast-cell infiltration and intracytoplasmic carbohydrate ratio
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Can houseplants improve indoor air quality by removing CO2 and increasing relative humidity?
High indoor CO2 concentrations and low relative humidity (RH) create an array of well-documented human health issues. Therefore, assessing houseplantsâ potential as a low-cost approach to CO2 removal and increasing RH is important.
We investigated how environmental factors such as âdryâ ( 0.30 m3 m-3) growing substrates, and indoor light levels (âlowâ 10 ”mol m-2 s-1, âhighâ 50 ”mol m-2 s-1 and âvery highâ 300 ”mol m-2 s-1), influence the plantsâ net CO2 assimilation (âAâ) and water-vapour loss. Seven common houseplant taxa â representing a variety of leaf types, metabolisms and sizes â were studied for their ability to assimilate CO2 across a range of indoor light levels. Additionally, to assess the plantsâ potential contribution to RH increase, the plantsâ evapo-transpiration (ET) was measured.
At typical âlowâ indoor light levels âAâ rates were generally low (< 3.9 mg hr-1). Differences between âdryâ and âwetâ plants at typical indoor light levels were negligible in terms of room-level impact. Light compensation points (i.e. light levels at which plants have positive âAâ) were in the typical indoor light range (1-50 ”mol m-2 s-1) only for two studied Spathiphyllum wallisii cultivars and Hedera helix; these plants would thus provide the best CO2 removal indoors. Additionally, increasing indoor light levels to 300 ”mol m-2 s-1 would, in most species, significantly increase their potential to assimilate CO2. Species which assimilated the most CO2 also contributed most to increasing RH
Effects of N-acetylcysteine and pentoxifylline on remote lung injury in a rat model of hind-limb ischemia/reperfusion injury
Overview paper: New insights into aerosol and climate in the Arctic
Motivated by the need to predict how the Arctic atmosphere will
change in a warming world, this article summarizes recent advances made by
the research consortium NETCARE (Network on Climate and Aerosols: Addressing
Key Uncertainties in Remote Canadian Environments) that contribute to our
fundamental understanding of Arctic aerosol particles as they relate to
climate forcing. The overall goal of NETCARE research has been to use an
interdisciplinary approach encompassing extensive field observations and a
range of chemical transport, earth system, and biogeochemical models. Several
major findings and advances have emerged from NETCARE since its formation in
2013. (1)Â Unexpectedly high summertime dimethyl sulfide (DMS) levels were
identified in ocean water (up to 75 nM) and the overlying atmosphere (up to
1 ppbv) in the Canadian Arctic Archipelago (CAA). Furthermore, melt ponds,
which are widely prevalent, were identified as an important DMS source (with
DMS concentrations of up to 6 nM and a potential contribution to atmospheric
DMS of 20 % in the study area). (2)Â Evidence of widespread particle
nucleation and growth in the marine boundary layer was found in the CAA in
the summertime, with these events observed on 41 % of days in a 2016
cruise. As well, at Alert, Nunavut, particles that are newly formed and grown
under conditions of minimal anthropogenic influence during the months of July
and August are estimated to contribute 20 % to 80 % of the 30â50 nm
particle number density. DMS-oxidation-driven nucleation is facilitated by
the presence of atmospheric ammonia arising from seabird-colony emissions,
and potentially also from coastal regions, tundra, and biomass burning. Via
accumulation of secondary organic aerosol (SOA), a significant fraction of the new
particles grow to sizes that are active in cloud droplet formation. Although
the gaseous precursors to Arctic marine SOA remain poorly defined, the
measured levels of common continental SOA precursors (isoprene and
monoterpenes) were low, whereas elevated mixing ratios of oxygenated volatile
organic compounds (OVOCs) were inferred to arise via processes involving the
sea surface microlayer. (3)Â The variability in the vertical distribution of
black carbon (BC) under both springtime Arctic haze and more pristine
summertime aerosol conditions was observed. Measured particle size
distributions and mixing states were used to constrain, for the first time,
calculations of aerosolâclimate interactions under Arctic conditions.
Aircraft- and ground-based measurements were used to better establish the BC
source regions that supply the Arctic via long-range transport mechanisms,
with evidence for a dominant springtime contribution from eastern and
southern Asia to the middle troposphere, and a major contribution from
northern Asia to the surface. (4)Â Measurements of ice nucleating particles
(INPs) in the Arctic indicate that a major source of these particles is
mineral dust, likely derived from local sources in the summer and long-range
transport in the spring. In addition, INPs are abundant in the sea surface
microlayer in the Arctic, and possibly play a role in ice nucleation in the
atmosphere when mineral dust concentrations are low. (5)Â Amongst multiple
aerosol components, BC was observed to have the smallest effective deposition
velocities to high Arctic snow (0.03 cm sâ1).</p
Preparation and characterisation of calcium phosphate cement made by poly(acrylic/itaconic) acid
Effect of Monosodium glutamate on rat cerebellum
Background and Objective: Monosodium glutamate (MSG) is used as a food additive. Several studies have reported the adverse effects of Monosodium glutamate on the testis and brain. This study was performed to determine the effect of Monosodium glutamate in rat cerebellum. Methods: In this experimental study, 24 adult wistar rats randomly allocated into three groups including experiment A, experiment B and control (C). The animals in experiment A and B were received 3g and 6g of MSG thoroughly mixed with their feeds for 14 days, respectively. Animals in control group were received MSG free diet. Food and water for rats to be free in all of experimental time. The rats were sacrificed on fifteen day. The cerebellum dissected and fixed with formalin 10% buffer and stained with hematoxylin and eosin. Results: Disorders and detachment were observed in Purkinje and granular cell layers. Neural cell distribution in granular layer redeuced in the experimental groups. Cellular degenerative changes in the granular layer of the experimental B were more severe than experimental group A. The mean number of neuron of the granular layer in the experimental A, B and control groups were 2750, 2140 and 3150, respectively. Conclusion: The consumption of monosodium glutamate dose dependly causes histopathological changes and reduces the number of the cerebellumllar neurons in adult rat
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