3,487 research outputs found
The Bering Sea ice cover during March 1979: Comparison of surface and satellite data with the Nimbus-7 SMMR
During March 1979, field operations were carried out in the Marginal Ice Zone (MIZ) of the Bering Sea. The field measurements which included oceanographic, meteorological and sea ice observations were made nearly coincident with a number of Nimbus-7 and Tiros-N satellite observations. The results of a comparison between surface and aircraft observations, and images from the Tiros-N satellite, with ice concentrations derived from the microwave radiances of the Nimbus-7 Scanning Multichannel Microwave Radiometer (SMMR) are given. Following a brief discussion of the field operations, including a summary of the meteorological conditions during the experiment, the satellite data is described with emphasis on the Nimbus-7 SMMR and the physical basis of the algorithm used to retrieve ice concentrations
Fitotoxicidade de alternativas herbicidas para a cultura do tomate para processamento industrial.
Objetivou-se com este trabalho avaliar a fitotoxicidade de alternativas herbicidas para a cultura do tomate industrial
Identification of GABA receptor genes and evidence of GABA signaling during embryogenesis of the sea urchin
Gamma-aminobutyric acid (GABA) is the principal inhibitory neurotransmitter in the
mammalian central nervous system and acts via ionotropic (GABAA-Rs) and metabotropic
(GABAB-Rs) receptors. GABAA-Rs are Cl- selective hetero-pentameric channels assembled by
combinations of 19 distinct gene products. Instead, GABAB-Rs are bi-subunit G-protein coupled
receptors linked to K+ or Ca2+ channels. Dysfunctions of GABA-signaling (GS) cause psychotic
disorders and correlate with epigenetic alterations, such as over-expression of DNA methyl
transferase-1 which in turn imposes iper-methylation of GABA-regulated genes. The sea urchin
embryo, which presents a rudimentary nervous system, offers a big opportunity to study the GS
and its potential epigenetic implications in a simple eukaryote model. To this purpose, we
performed a comprehensive in silico analysis of the sea urchin genome and identified a 450 Kb
long cluster containing two genes encoding for the GABAB-R subunits, and two genes
respectively encoding for a \u3b1/\u3b3/\u3b5-type and a \u3b2/\u3c1/\u3b4/\u3c4/\u3c0-type GABA
B
A-R subunit. From an
evolutionary perspective, this result revealed a unique genomic organization of these genes in
sea urchin. Next, to preliminarily evaluate the role of GS during development, Paracentrotus
lividus embryos were cultured in the presence of GABA at concentrations ranging from 0.01 to
1.0 mM. Compared to controls, treated embryos showed aberrations in axial patterning, with a
dose-dependent effect. In particular, at 48 hours post-fertilization control embryos were normal
bilateral symmetric plutei whereas GABA-treated embryos displayed a radial organization with
supranumerary spicules. Washout experiments allowed to determine that the period of
sensitivity is restricted from the blastula to the gastrula stage. Altogether, these results suggest
that dysregulation of GS affects the polarization of the ectoderm. Although preliminary, this
study provide the first evidence of GS activity during development of echinoderms
Antifungals, arthropods and antifungal resistance prevention: lessons from ecological interactions
Arthropods can produce a wide range of antifungal compounds, including specialist proteins, cuticular products, venoms and haemolymphs. In spite of this, many arthropod taxa, particularly eusocial insects, make use of additional antifungal compounds derived from their mutualistic association with microbes. Because multiple taxa have evolved such mutualisms, it must be assumed that, under certain ecological circumstances, natural selection has favoured them over those relying upon endogenous antifungal compound production. Further, such associations have been shown to persist versus specific pathogenic fungal antagonists for more than 50 million years, suggesting that compounds employed have retained efficacy in spite of the pathogens' capacity to develop resistance. We provide a brief overview of antifungal compounds in the arthropods' armoury, proposing a conceptual model to suggest why their use remains so successful. Fundamental concepts embedded within such a model may suggest strategies by which to reduce the rise of antifungal resistance within the clinical milieu
Open orbifold Gromov-Witten invariants of [C^3/Z_n]: localization and mirror symmetry
We develop a mathematical framework for the computation of open orbifold
Gromov-Witten invariants of [C^3/Z_n], and provide extensive checks with
predictions from open string mirror symmetry. To this aim we set up a
computation of open string invariants in the spirit of Katz-Liu, defining them
by localization. The orbifold is viewed as an open chart of a global quotient
of the resolved conifold, and the Lagrangian as the fixed locus of an
appropriate anti-holomorphic involution. We consider two main applications of
the formalism. After warming up with the simpler example of [C^3/Z_3], where we
verify physical predictions of Bouchard, Klemm, Marino and Pasquetti, the main
object of our study is the richer case of [C^3/Z_4], where two different
choices are allowed for the Lagrangian. For one choice, we make numerical
checks to confirm the B-model predictions; for the other, we prove a mirror
theorem for orbifold disc invariants, match a large number of annulus
invariants, and give mirror symmetry predictions for open string invariants of
genus \leq 2.Comment: 44 pages + appendices; v2: exposition improved, misprints corrected,
version to appear on Selecta Mathematica; v3: last minute mistake found and
fixed for the symmetric brane setup of [C^3/Z_4]; in pres
Lift-up, Kelvin-Helmholtz and Orr mechanisms in turbulent jets
Three amplification mechanisms present in turbulent jets, namely lift-up, Kelvin–Helmholtz and Orr, are characterized via global resolvent analysis and spectral proper orthogonal decomposition (SPOD) over a range of Mach numbers. The lift-up mechanism was recently identified in turbulent jets via local analysis by Nogueira et al. (J. Fluid Mech., vol. 873, 2019, pp. 211–237) at low Strouhal number ( St ) and non-zero azimuthal wavenumbers ( m ). In these limits, a global SPOD analysis of data from high-fidelity simulations reveals streamwise vortices and streaks similar to those found in turbulent wall-bounded flows. These structures are in qualitative agreement with the global resolvent analysis, which shows that they are a response to upstream forcing of streamwise vorticity near the nozzle exit. Analysis of mode shapes, component-wise amplitudes and sensitivity analysis distinguishes the three mechanisms and the regions of frequency–wavenumber space where each dominates, finding lift-up to be dominant as St/m→0 . Finally, SPOD and resolvent analyses of localized regions show that the lift-up mechanism is present throughout the jet, with a dominant azimuthal wavenumber inversely proportional to streamwise distance from the nozzle, with streaks of azimuthal wavenumber exceeding five near the nozzle, and wavenumbers one and two most energetic far downstream of the potential core
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