A Study on Data Protection in Cloud Environment

Data protection in the online environment pertains to the safeguarding of sensitive or important data kept, analyzed, or sent in cloud-based systems. It entails assuring data confidentiality, integrity, and availability, as well as adhering to appropriate data protection requirements. In a nutshell, cloud data protection seeks to protect data against unauthorized access, deletion, or breaches while retaining its accuracy and accessible to authorized users. This is accomplished in the cloud environment using various security measures, encryption approaches, access controls, disaster recovery and backup processes, and constant monitoring and threat detection.  The research significance of data protection in the cloud environment can be summarized as follows: Security and Privacy: Research in data protection in the cloud helps address the security and privacy concerns associated with storing and processing sensitive data in cloud-based systems. It explores and develops advanced security mechanisms, encryption techniques, and access controls to protect data from unauthorized access, data breaches, and privacy violations. Trust and Confidence: Research in data protection contributes to building trust and confidence in cloud computing. By developing robust security solutions and demonstrating their effectiveness, research helps alleviate concerns about data security and privacy, fostering greater adoption of cloud services by organizations and individuals. Compliance and Regulations: Cloud computing often involves compliance with data protection regulations and industry standards. Research in this area explores the legal and regulatory aspects of data protection in the cloud and helps organizations understand and comply with relevant requirements. Data Resilience and Recovery: Research in data protection focuses on ensuring data resilience and developing efficient data recovery mechanisms in the cloud. It explores backup and disaster recovery strategies, data replication techniques, and data loss prevention methods to minimize downtime, recover data promptly, and maintain business continuity in the event of system failures or disasters. By addressing these research areas, studies on data protection in the cloud environment contribute to enhancing security, privacy, compliance, and resilience in cloud computing. They provide valuable insights, practical solutions, and guidelines for organizations and service providers to protect data effectively and maintain the trust of users in cloud-based services. The weighted product method approach is commonly used to choose the best data protection in cloud environment. CCSS1, CCSS2, CCSS3, CCSS4, CCSS5 data visibility, data integrity, Maintains compliance, Data security, Data storage. From the result it is seen that CCSS2 got highest rank whereas CCSS5 got lowest rank According to the results, CCSS2 was ranked first

Prevalence of Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma in Upper Egypt

<p>Abstract</p> <p>Background</p> <p>Pseudoexfoliation (PXF) is a recognized risk factor for developing cataract, glaucoma and lens dislocation. PXF is also associated with increased risk of complications during cataract surgery due to poor mydriasis and zonular weakness. The aim of this study is to report the prevalence of pseudoexfoliation among Upper Egyptians attending the ophthalmology clinic of Assiut University Hospital.</p> <p>Methodology</p> <p>A retrospective, chart review study conducted in the period from February 2002 to August 2009. A total of 7738 patients aged 40 years or older attending the general ophthalmic clinics were included in this study. A detailed evaluation including ophthalmic and general history, slit lamp biomicroscopy, intraocular pressure measurement, gonioscopy and dilated eye examination were performed. Patients with pseudoexfoliative material on the anterior lens surface and ⁄ or the pupillary margin in either or both eyes were labeled as having PXF.</p> <p>Results</p> <p>Out of the 7738 patients included, three hundred twenty (4.14%) subjects had PXF. Mean age of PXF group was 68.15 years (SD 8.16, range 40-92 years). PXF was bilateral in 82.2% of cases. It was significantly associated with cataract, glaucoma and hearing loss. Of the PXF patients, 65% had cataract, 30.3% had glaucoma and 8.1% had hearing loss.</p> <p>Conclusion</p> <p>Pseudoexfoliation appears to be a common disorder in older individuals in Upper Egypt.</p

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Not AvailableHigh fertilizer use efficiency in rice (Oryza sativa L.)-based cropping systems in Indo-Gangetic Plains (IGP) is not achieved because farmers’ fertilizer practices (FFP) and blanket state recommendations (BSR) do not take into account the site-specific variability of nutrient availability in the soil. We evaluated the site-specific nutrient management (SSNM) option against existing FFP, blanket state recommendation (BSR), improved BSR (IBSR i.e., 25 % higher than BSR), and state soil testing laboratory recommendation (STLR) in six pre-dominant rice-based cropping systems namely wheat–rice (W–R), mustard–rice (M–R), potato–rice (P–R), garlic–rice (G–R), chickpea–rice (C–R) and berseem fodder–rice (B–R) in terms of yield gain, economics, nutrient harvest index, soil fertility, and apparent nutrient balances. System rice equivalent yield (SREY) improved by 15.7, 9.5, 13.9 and 30 %, in SSNM over BSR, IBSR, STLR and FFP, respectively. SSNM involved additional cost of ` 2940–5291 ha−1 over BSR and ` 5492–10120 ha−1 over FFP under different cropping systems but contributed higher added net return of ` 23236–75056 ha−1 and ` 39577–143899 ha−1 over BSR and FFP, respectively. The output: input ratio and nutrient harvest index for N, P, K were also highest in SSNM. At the end of the experiment, soil available N, Olsen-P and available K content were either maintained or improved over their initial values in SSNM treatments, whereas soil available K in FFP declined by −1.65 % and increased over initial content in BSR and STLR in 0– 15 cm soil profile depth. After three crop cycles, apparent N and P balances were positive in all the cropping systems and fertilizer treatments; only exception was a negative N balance in C–R and B–R systems in different fertilizer treatments. The apparent K balances were negative in all the cropping systems irrespective of nutrient management options. But, the magnitude of negative balance was lower in plots received SSNM treatment as compared to other nutrient management strategies, indicating a potential for improving yields, nutrient use efficiency and farm profit without deteriorating soil fertility in different rice based systems in IGP.Not Availabl

Newer insights into the mechanism of action of <it>Psidium guajava </it>L. leaves in infectious diarrhoea

<p>Abstract</p> <p>Background</p> <p><it>Psidium guajava </it>L., Myrtaceae, is used widely in traditional medicine for the treatment of diarrhoea, dysentery, gastroenteritis, stomachaches, and indigestion. However, the effect of the leaf extract of <it>P. guajava </it>on the pathogenesis of infectious diarrhoea has not been studied. The present study evaluates the effect of a hot aqueous extract (decoction) of dried leaves of <it>P. guajava </it>on parameters associated with pathogenicity of infectious diarrhoea. The aim was to understand its possible mechanism(s) of action in controlling infectious diarrhoea and compare it with quercetin, one of the most reported active constituents of <it>P. guajava </it>with antidiarrhoeal activity.</p> <p>Methods</p> <p>The crude decoction and quercetin were studied for their antibacterial activity and effect on virulence features of common diarrhoeal pathogens viz. colonization of epithelial cells and production and action of enterotoxins. Colonization as measured by adherence of enteropathogenic <it>Escherichia coli </it>(EPEC) and invasion of enteroinvasive <it>E. coli </it>(EIEC) and <it>Shigella flexneri </it>was assessed using HEp-2 cell line. The production of <it>E. coli </it>heat labile toxin (LT) and cholera toxin (CT) and their binding to ganglioside monosialic acid (GM1) were studied by GM1-ELISA whereas the production and action of <it>E. coli </it>heat stable toxin (ST) was assessed by suckling mouse assay.</p> <p>Results</p> <p>The decoction of <it>P. guajava </it>showed antibacterial activity towards <it>S. flexneri </it>and <it>Vibrio cholerae</it>. It decreased production of both LT and CT and their binding to GM1. However, it had no effect on production and action of ST. The decoction also inhibited the adherence of EPEC and invasion by both EIEC and <it>S. flexneri </it>to HEp-2 cells. Quercetin, on the other hand, had no antibacterial activity at the concentrations used nor did it affect any of the enterotoxins. Although it did not affect adherence of EPEC, it inhibited the invasion of both EIEC and <it>S. flexneri </it>to HEp-2 cells.</p> <p>Conclusion</p> <p>Collectively, the results indicate that the decoction of <it>P. guajava </it>leaves is an effective antidiarrhoeal agent and that the entire spectrum of its antidiarrhoeal activity is not due to quercetin alone.</p

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field.This article is published as Klionsky, Daniel J., Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Steffen Abel, Hagai Abeliovich et al. "Guidelines for the use and interpretation of assays for monitoring autophagy." autophagy 17, no. 1 (2021): 1-382. doi:https://doi.org/10.1080/15548627.2020.1797280. Works produced by employees of the U.S. Government as part of their official duties are not copyrighted within the U.S. The content of this document is not copyrighted