Synthesis, Characterization and Inhibitive Effect of 1-[(4-methylPhenyl) Sulfonyl]-4-pyridine-2-ylpiperazine on Corrosion of Mild Steel in HCl Medium

A novel inhibitor, 1-[(4-methylphenyl)Sulfonyl]-4–pyridine-2-ylpiperazine (MSPP)  has been  synthesized and characterized using FT-IR, 1H NMR,13C NMR , LC-MS  and UV-visible  spectroscopy methods.The  inhibitive effect of 1-[(4-methylphenyl)sulfonyl]-4-pyridin-2-ylpiperazine(MSPP) on the corrosion of mild steel in 1M HCl was investigated by weight loss, potentiodynamic polarization and electrochemical impedance spectroscopy (EIS) techniques. The efficiency of the inhibitor increases with the increase in the inhibitor concentration and decrease with a rise in temperature. Potentiodynamic polarization study showed that the inhibitor acts as mixed type. EIS finding showed that the change in the impedance parameters (Rct and Cdl), with the variation in MSPP concentration is due to the adsorption of active molecules leading to the formation of protective layer on the surface of mild steel. The UV-visible absorption spectra indicate the formation of a MSPP-Fe complex. The adsorption data fitted with Langmuir adsorption isotherm. Thermodynamic parameters such as activation energy (Ea), free energy change (ΔGads ), enthalpy change (ΔHads ) and entropy change (ΔSads ) were  also evaluated and discussed in detail. Surface analysis by AFM and SEM confirmed the formation of protective coating on the mild steel surface. Quantum chemical calculation were also performed using density functional theory

Study the normative datas of vestibular evoked myogenic potential and compare with migraine patients

SUMMARY: VEMP arelatively new diagnostic tool was studied on 50 migraine patients and compared with age and sex matched controls. There was no significant variations of p13 and n23 latencies in either the controls or the migraine patients. The latencies did not change with regard to the age, different modes of neck torsion or the placement of inverting electrodes at different sites. P13-n23 ampltude was significantly higher when the neck was lifted forwards and turned away from the source of stimulus. Similarly the amplitude was greater when the reference electrode was placed at the sternum compared to wrist and mastoid. The amplitude decreases significantly after 50 years of age. In migraine patients with or without vertigo the amplitude showed a significant decrease. The magnitude of decrease in migraine patients was much higher. CONCLUSION: VEMP a relatively new diagnostic test to assess the vestibular pathway was studied in relation to age , neck torsion and placement of inverting electrode. A sincere attempt was also made to study the changes in VEMP in migraine patients with age-sex matched controls. VEMP response did not show much significant change in p13 and n23 latencies over different age groups but p13-n23 amplitude showed a significant decrease in the elderly which could be due to physiological degenerative changes of saccule and other vestibular apparatus including the vestibulespinal tract due to advancing age. Different modes of neck torsion did not produce any significant change in p13 or n23 latencies but there was a significant increase in p13-n23 amplitude when the head was lifted upwards and neck turned away from the source of stimulus indicating that the magnitude of VEMP amplitude correlates with the degree of neck torsion. The more nearer the inverting electrode is to the active electrode greater is the VEMP response as evidenced by the robust amplitude seen when it was placed over the sternum. The amplitude of VEMP in migraine patients, more so in migraine patients with vertigo was significantly lower compared to the controls probably due to the habituation deficit in cortical evoked potential which might be associated with hypofunction of subcortical serotoninergic input to vestibular nucleus. Although an honest attempt has been made, the study has its limitation since not much work has been done in the Indian sub-continent to compare the datas. Apart from inadequate number of subjects in the older age group a high level of motivation is necessary to elicit a good and robust response. A better understanding of the pathophysiology of migraine would throw more light on the usefulness of VEMP to demarcate migraine and vertigo associated with migraine. Further studies is being done on the usefulness of VEMP on this line

Purification and Characterstics of Peroxidase from Two Varities of Tulsi and Neem

ABSTRACT Peroxidase was extracted from different varieties of tulsi and neem and its purification by gel filteration. Medicinal plants are premier adaptogen helping the body and mind to adopt and cope with a wide range of physical, emotional, chemical and infectious stresses and restore physiological and psychological functions to a normal healthy state. The isoenzyme, peroxidase stands responsible for their antioxidant capacity which in turn contributes towards their medicinal properties. Ocimum tenuiflorum , Ocimum gratissimum varieties of tulsi and Azadirachta indica, Melia azadirachta varieties of neem were studied for peroxidase analysis.. The optimum pH and temperature of peroxidase were found to be 6.5 and 40ºC. This was studied to understand the variation between single species at protein level. Protein profiling was done in both Native PAGE and SDS PAGE

Comparative Study of Ethanol Production from Different Industrial Waste and its Managerial Benefits

ABSTRACT In the quest of a search for an alternative to the petroleum products, Ethanol has effectively fulfilled the need as an alternative to petrol .The necessity to find effective, feasible, affordable and cheaper sources for its production are coming into focus. This work is that done in this perspective where various sources are been tested in their ability to support the growth of yeast and in turn in the production of ethanol. Sources like Sugarcane baggasse, Cassava waste, potato waste, Wheat bran, Corn stalk and leaf and various combinations between themselves are tested for the production of ethanol by various alterations in pH.

EFFECT OF GLOBAL WARMING ON DNA CONTENT AND COI GENE EXPRESSION IN BUTTERFLY

Global Warming is an average increase in the temperature of the atmosphere near the Earth’s surface and in the Troposphere, which can contribute to changes in global climate patterns. Changing climate may promote harmful physical impacts such as effects on weather and radioactive forcing. Global warming causes the rise in the sea level and ocean temperature. This change affects the ecosystem and lifestyle of living organism. The butterfly (Tawny Coster) was collected from Chennai,chengalpattu and Tanjore, Tamil Nadu.The Genomic DNA was isolated from the samples and the DNA was amplified in the polymerase chain reaction (PCR). Gene specific PCR was used to find the presence of COI gene. RNA levels are determined by reverse transcriptase polymerase chain reaction. The purpose of this research work is helpful to find out how Global Warming is affecting small creatures. If this Global Warming is continuously increasing it leads to extinction of small creatures

A Complexity Reduction Method for Extended Min-Sum based Nonbinary LDPC Decoder

Abstract—Nonbinary LDPC codes are a class of linear block codes having the performance closer to Shannon’s limit. Codes defined over higher order of Galois field, have increased computation complexity and thereby it put forth the challenges in efficient hardware realization of the decoder. In this paper, modifications in the Non-binary LDPC decoder to obtain reduced configuration sets, aimed to reduce the decoding complexity is proposed. Configuration sets are the possible combinations of the message sets that are involved in the parity check equation of LDPC decoder. Min-sum algorithm based decoder is modelled with the specification of IEEE 802.11n standard, with the codelength of 648, rate for GF (4) Galois field, over the AWGN channel. The mathematical formulation of the proposed complexity reduction methodology is presented. The decoding performance of reduced configuration sets is analyzed and it is found that the complexity is reduced by an average of 83%, with negligible degradation in performance in terms of bit error rate