Pre-seismic ionospheric anomalies detected before the 2016 Taiwan earthquake

On Feb. 5 2016 (UTC), an earthquake with moment magnitude 6.4 occurred in southern Taiwan, known as the 2016 (Southern) Taiwan earthquake. In this study, evidences of seismic earthquake precursors for this earthquake event are investigated. Results show that ionospheric anomalies in Total Electric Content (TEC) can be observed before the earthquake. These anomalies were obtained by processing TEC data, where such TEC data are calculated from phase delays of signals observed at densely arranged ground-based stations in Taiwan for Global Navigation Satellite Systems. This shows that such anomalies were detected within 1 hour before the event

First Data Release of the Hyper Suprime-Cam Subaru Strategic Program

The Hyper Suprime-Cam Subaru Strategic Program (HSC-SSP) is a three-layered imaging survey aimed at addressing some of the most outstanding questions in astronomy today, including the nature of dark matter and dark energy. The survey has been awarded 300 nights of observing time at the Subaru Telescope and it started in March 2014. This paper presents the first public data release of HSC-SSP. This release includes data taken in the first 1.7 years of observations (61.5 nights) and each of the Wide, Deep, and UltraDeep layers covers about 108, 26, and 4 square degrees down to depths of i~26.4, ~26.5, and ~27.0 mag, respectively (5sigma for point sources). All the layers are observed in five broad bands (grizy), and the Deep and UltraDeep layers are observed in narrow bands as well. We achieve an impressive image quality of 0.6 arcsec in the i-band in the Wide layer. We show that we achieve 1-2 per cent PSF photometry (rms) both internally and externally (against Pan-STARRS1), and ~10 mas and 40 mas internal and external astrometric accuracy, respectively. Both the calibrated images and catalogs are made available to the community through dedicated user interfaces and database servers. In addition to the pipeline products, we also provide value-added products such as photometric redshifts and a collection of public spectroscopic redshifts. Detailed descriptions of all the data can be found online. The data release website is https://hsc-release.mtk.nao.ac.jp/.Comment: 34 pages, 20 figures, 7 tables, moderate revision, accepted for publication in PAS

The Hyper Suprime-Cam SSP survey: Overview and survey design

Hyper Suprime-Cam (HSC) is a wide-field imaging camera on the prime focus of the 8.2-m Subaru telescope on the summit of Mauna Kea in Hawaii. A team of scientists from Japan, Taiwan, and Princeton University is using HSC to carry out a 300-night multi-band imaging survey of the high-latitude sky. The survey includes three layers: the Wide layer will cover 1400 deg2 in five broad bands (grizy), with a 5 σ point-source depth of r ≈ 26. The Deep layer covers a total of 26 deg2 in four fields, going roughly a magnitude fainter, while the UltraDeep layer goes almost a magnitude fainter still in two pointings of HSC (a total of 3.5 deg2). Here we describe the instrument, the science goals of the survey, and the survey strategy and data processing. This paper serves as an introduction to a special issue of the Publications of the Astronomical Society of Japan, which includes a large number of technical and scientific papers describing results from the early phases of this survey

Additional file 2 of Deep learning-based automatic-bone-destruction-evaluation system using contextual information from other joints

Additional file 2: Table S2. Final settings of hyperparameters (JSN). Each classification model’s final settings of hyperparameters for each target joint are shown. "Wrist" represents the multangular-navicular, the capitate-navicular-lunate, and the radiocarpal joint. Note: JSN, joint space narrowing; FC, fully connected; PIP, proximal interphalangeal; MCP, metacarpophalangeal; CMC, carpometacarpal

Additional file 1 of Deep learning-based automatic-bone-destruction-evaluation system using contextual information from other joints

Additional file 1: Table S1. Final settings of hyperparameters (erosion). Each classification model’s final settings of hyperparameters for each target joint are shown. “Wrist” represents the navicular, the lunate, the radius, and the ulna. Note: FC, fully connected; PIP, proximal interphalangeal; IP, interphalangeal; MCP, metacarpophalangeal; CMC-M, carpometacarpal joint of the thumb and multangular

Characteristics of organic light-emitting devices consisting of dye-doped spin crossover complex films

Two organic light-emitting devices (OLEDs) were fabricated to investigate the mechanism of electroluminescence (EL) switching accompanying the spin transition of [Fe(dpp)2](BF4)2 (dpp = 2,6-di(pyrazol-1-yl)pyridine) observed in an OLED with the structure indium tin oxide (ITO)/[Fe(dpp)2](BF4)2:chlorophyll a/Al, consisting of a chlorophyll a (Chl a)-doped [Fe(dpp)2](BF4)2 film. One OLED consisted of poly(N-vinylcarbazole) (PVK) between an ITO electrode and the active layer, and the other contained the electron transporting dye Nile Red (NR) as an emitting dopant material instead of the hole transporting Chl a. In both devices ITO/PVK/[Fe(dpp)2](BF4)2:Chl a/Al and ITO/[Fe(dpp)2](BF4)2:NR/Al, EL emission from the dye compound was observed, irrespective of the spin state of [Fe(dpp)2](BF4)2. It was determined that the EL switching accompanying the spin transition was dominated by a change in the molecular orbital level concerning electron transport in [Fe(dpp)2](BF4)2

Precise immunofluorescence canceling for highly multiplexed imaging to capture specific cell states.

Funder: - Medical Research Center Initiative for High Depth Omics.Funder: - MEXT | JST | Fusion Oriented REsearch for disruptive Science and Technology (FOREST), JPMJFR2251.Cell states are regulated by the response of signaling pathways to receptor ligand-binding and intercellular interactions. High-resolution imaging has been attempted to explore the dynamics of these processes and, recently, multiplexed imaging has profiled cell states by achieving a comprehensive acquisition of spatial protein information from cells. However, the specificity of antibodies is still compromised when visualizing activated signals. Here, we develop Precise Emission Canceling Antibodies (PECAbs) that have cleavable fluorescent labeling. PECAbs enable high-specificity sequential imaging using hundreds of antibodies, allowing for reconstruction of the spatiotemporal dynamics of signaling pathways. Additionally, combining this approach with seq-smFISH can effectively classify cells and identify their signal activation states in human tissue. Overall, the PECAb system can serve as a comprehensive platform for analyzing complex cell processes

Precise immunofluorescence canceling for highly multiplexed imaging to capture specific cell states

Abstract Cell states are regulated by the response of signaling pathways to receptor ligand-binding and intercellular interactions. High-resolution imaging has been attempted to explore the dynamics of these processes and, recently, multiplexed imaging has profiled cell states by achieving a comprehensive acquisition of spatial protein information from cells. However, the specificity of antibodies is still compromised when visualizing activated signals. Here, we develop Precise Emission Canceling Antibodies (PECAbs) that have cleavable fluorescent labeling. PECAbs enable high-specificity sequential imaging using hundreds of antibodies, allowing for reconstruction of the spatiotemporal dynamics of signaling pathways. Additionally, combining this approach with seq-smFISH can effectively classify cells and identify their signal activation states in human tissue. Overall, the PECAb system can serve as a comprehensive platform for analyzing complex cell processes