13 research outputs found
Bullous Eruption Associated With Dihydropyridines With Cross Reactivity
The spectrum of cutaneous eruptions associated with
dihydropyridines is extensive, varying from exanthemas to severe adverse
events. We report a case of bullous eruption, one month after starting nicardipine
and lercanidipine. The same symptoms recurred few days after taking nitrendipine
DRESS syndrome induit par la sulfasalazine et associé à une réactivation virale à virus Epstein Barr
Hydroxychloroquine-induced acute generalized exanthematous pustulosis with positive patch-testing
Lichen Associated with Metformin
We report an exceptional case of bullous lichen induced by metformin in a patient with
diabetes mellitus
Bullous Eruption Associated With Dihydropyridines With Cross Reactivity
The spectrum of cutaneous eruptions associated with
dihydropyridines is extensive, varying from exanthemas to severe adverse
events. We report a case of bullous eruption, one month after starting nicardipine
and lercanidipine. The same symptoms recurred few days after taking nitrendipine
Loss of Sour Taste Is the Striking Feature among Four Basic Taste Qualities in Tunisian COVID-19 Patients
Background: Taste disorders (TDs) have been reported to be very common in patients suffering from coronavirus disease 2019 (COVID-19), which is caused by the SARS-CoV-2 virus. In most of the hitherto conducted studies, a gustatory assessment was performed on the basis of surveys or self-reports by patients. The aim of our study was to undertake an objective assessment of four basic taste qualities by conducting tasting sessions that allowed detection thresholds in COVID-19 Tunisian patients and to study their associations with inflammation. Methods: This analytical cross-sectional study was conducted on 89 patients aged between 21 to 70 years who had been diagnosed with COVID-19. We used Burghart taste strips to assess taste perception of the four taste qualities, i.e., sour, bitter, sweet, and salty. Serum levels of interleukin-1β (IL-1β), interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-α), and C-reactive protein (CRP) were measured. Results: Taste disorders were reported by 40.4% of the patients, while objective assessments revealed that 63.8% of participants were suffering from hypogeusia and/or ageusia. Sour taste was the most altered (70.8%) gustatory quality. Patients with severe COVID-19 had significantly lower sour and bitter taste scores when compared to patients with minor/moderate forms. There was no significant association between serum inflammatory markers and taste disorders. However, the relationship between bitter and sweet taste qualities and IL-1β levels was significant (p = 0.018 and p = 0.041). Conclusions: Our results demonstrate the interest in the objective assessment of taste dysfunctions in COVID-19 patients