130 research outputs found
Evidence for melt leakage from the Hawaiian plume above the mantle transition zone
Dehydration reactions at the top of the mantle transition zone (MTZ) can stabilize partial melt in a seismic low-velocity layer (LVL), but the seismic effects of temperature, melt and volatile content are difficult to distinguish. We invert P-to-S receiver function phases converted at the top and bottom of a LVL above the MTZ beneath Hawaii. To separate the thermal and melting related seismic anomalies, we carry out over 10 million rock physics inversions. These inversions account for variations arising from the Clapeyron slope of phase transition, bulk solid composition, dihedral angle, and mantle potential temperature. We use two independent seismic constraints to evaluate the temperature and shear wave speed within the LVL. The thermal anomalies reveal the presence of a hot and seismically slow plume stem surrounded by a âhaloâ of cold and fast mantle material. In contrast to this temperature distribution, the plume stem contains less than 0.5 vol% melt, while the surrounding LVLâwithin the coverage areaâcontains up to 1.7 vol% melt, indicating possible lateral transport of the melt. When compared to the melting temperatures of mantle rocks, the temperature within the LVL, calculated from seismic observations of MTZ thickness, suggests that the observed small degrees of melting are sustained by the presence of volatiles such as CO2 and H2O. We estimate the Hawaiian plume loses up to 1.9 Mt/yr H2O and 10.7 Mt/yr CO2 to the LVL, providing a crucial missing flux for global volatile cycles
Seismic anisotropy indicates organised melt beneath the Mid-Atlantic Ridge aids seafloor spreading
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RESEARCH ARTICLE| AUGUST 04, 2023
Seismic anisotropy indicates organized melt beneath the Mid-Atlantic Ridge aids seafloor spreading
J.M. Kendall; D. Schlaphorst; C.A. Rychert; N. Harmon; M. Agius; S. Tharimena
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Geology (2023) 51 (10): 968â972.
https://doi.org/10.1130/G51550.1
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Abstract
Lithospheric plates diverge at mid-ocean ridges and asthenospheric mantle material rises in response. The rising material decompresses, which can result in partial melting, potentially impacting the driving forces of the system. Yet the geometry and spatial distribution of the melt as it migrates to the ridge axis are debated. Organized melt fabrics can cause strong seismic anisotropy, which can be diagnostic of melt, although this is typically not found at ridges. We present anisotropic constraints from an array of 39 ocean-bottom seismometers deployed on 0â80 Ma lithosphere from March 2016 to March 2017 near the equatorial Mid-Atlantic Ridge (MAR). Local and SKS measurements show anisotropic fast directions away from the ridge axis, which are consistent with strain and associated fabric caused by plate motions with short delay times, ÎŽt (<1.1 s). Near the ridge axis, we find several ridge-parallel fast splitting directions, Ï, with SKS ÎŽt that are much longer (1.7â3.8 s). This is best explained by ridge-parallel sub-vertical orientations of sheet-like melt pockets. This observation is much different than anisotropic patterns observed at other ridges, which typically reflect fabric related to plate motions. One possibility is that thicker sub-ridge lithosphere with steep sub-ridge topography beneath slower spreading centers focuses melt into vertical, ridge-parallel melt bands, which effectively weakens the plate. Associated buoyancy forces elevate the sub-ridge plate, providing greater potential energy and enhancing the driving forces of the plates
Predictors of voter support for the legalization of recreational cannabis use and supply via a national referendum
Background: A national referendum to legalise recreational cannabis use and supply in New Zealand via the Cannabis Legalisation and Control Bill (CLCB) was recently narrowly defeated. Understanding the underlying factors for this result can inform the cannabis legalisation debate in other countries. Aims: To investigate predictors of voter support for and opposition to the CLCB. Method: A representative population panel of 1,022 people completed an online survey of intended voting on the CLCB referendum, which included questions on demographics, drug use history, medicinal cannabis, perceptions of the health risk and moral views of cannabis use, political affiliation, religiosity, community size and reading of the CLCB. Regression models were developed to predict support for the CLCB, with additional predictor variables added over successive iterations. Results: The most robust predictors of support for the CLCB were use of and policy support for medicinal cannabis use, voting for a left-wing political party, having a positive moral view of cannabis use, living in a small town and having read the CLCB. Predictors of opposing the CLCB were voting for right-wing parties, considering "frequent " cannabis use to be a high health risk, and lifetime use of other drugs. Age, ethnicity, education, employment status, religiosity and lifetime cannabis use were not significant predictors after controlling for other variables. Conclusions: Support for cannabis legalization was not based on broad demographics, but rather specific views concerning the medicinal benefit, morality of cannabis use, health risk of frequent cannabis use, political party affiliation, and knowledge of the proposed regulatory controls of the CLCB. The influence of moral views of cannabis use on voting behaviour suggest the need to debate the right to use cannabis. The importance of knowledge of the proposed regulatory controls of the CLCB on voting underlines the need to raise awareness of proposed regulatory controls during debate
Source regions of infragravity waves recorded at the bottom of the equatorial Atlantic Ocean, using OBS of the PIâLAB experiment
Infragravity waves are generated along coasts, and some small fraction of their energy escapes to the open oceans and propagates with little attenuation. Due to the scarcity of deepâocean observations of these waves, the mechanism and the extent of the infragravity waves energy leakage from the coasts remains poorly understood. Understanding the generation and pathways of infragravity wave energy is important among others for understanding the breakup of iceâshelves and the contamination of highâresolution satellite radar altimetry measurements of sea level. We examine data from 37 differential pressure gauges of Ocean Bottom Seismometers (OBS) near the equatorial midâAtlantic ridge, deployed during the Passive Imaging of the LithosphereâAsthenosphere Boundary (PIâLAB) experiment. We use the beamforming technique to investigate the incoming directions of infragravity waves. Next, we develop a graphâtheoryâbased global backâprojection method of noise crossâcorrelation function envelopes, which minimizes the effects of array geometry using an adaptive weighting scheme. This approach allows us to locate the sources of the infragravity energy. We assess our observations by comparing to a global model of infragravity wave heights. Our results reveal strong coherent energy from sources and/or reflected phases at the west coast of Africa and some sources from South America. These energy sources are in good agreement with the global infragravity wave model. In addition, we also observe infragravity waves arriving from North America during specific events that mostly occur during OctoberâFebruary 2016. Finally, we find indications of waves that propagate with little attenuation, long distances through sea ice, reflecting off Antarctica
Imaging slab-transported fluids and their deep dehydration from seismic velocity tomography in the Lesser Antilles subduction zone
Volatiles play a pivotal role in subduction zone evolution, yet their pathways remain poorly constrained. Studying the Lesser Antilles subduction zone can yield new constraints, where old oceanic lithosphere formed by slow-spreading subducts slowly. Here we use local earthquakes recorded by the temporary VoiLA (Volatile recycling in the Lesser Antilles) deployment of ocean-bottom seismometers in the fore- and back-arc to characterize the 3-D seismic structure of the north-central Lesser Antilles subduction zone. Along the slab top, mapped based on seismicity, we find low Vp extending to 130â150 km depth, deeper than expected for magmatic oceanic crust. The slab\u27s most prominent, elevated Vp/Vs anomalies are beneath the fore- and back-arc offshore Guadeloupe and Dominica, where two subducted fracture zones lie with the obliquely subducting boundary between Proto-Caribbean and Equatorial Atlantic lithosphere. These structures, therefore, enhance hydration of the oceanic lithosphere as it forms and evolves and the subsequent dehydration of mantle serpentinite when subducted. Above the slab, we image the asthenosphere wedge as a high Vp/Vs and moderate Vp feature, indicating slab-dehydrated fluids rising through the overlying cold boundary layer that might induce melting further to the west. Our results provide new evidence for the impact of spatially-variable oceanic plate formation processes on slab dehydration and mantle wedge volatile transfer that ultimately impact volcanic processes at the surface, such as the relatively high magmatic output observed on the north-central islands in the Lesser Antilles
Multicenter study evaluating the Vitek MS system for identification of medically important yeasts
The optimal management of fungal infections is correlated with timely organism identification. Matrix-assisted laser desorption ionizationâtime of flight (MALDI-TOF) mass spectrometry (MS) is revolutionizing the identification of yeasts isolated from clinical specimens. We present a multicenter study assessing the performance of the Vitek MS system (bioMĂ©rieux) in identifying medically important yeasts. A collection of 852 isolates was tested, including 20 Candida species (626 isolates, including 58 C. albicans, 62 C. glabrata, and 53 C. krusei isolates), 35 Cryptococcus neoformans isolates, and 191 other clinically relevant yeast isolates; in total, 31 different species were evaluated. Isolates were directly applied to a target plate, followed by a formic acid overlay. Mass spectra were acquired using the Vitek MS system and were analyzed using the Vitek MS v2.0 database. The gold standard for identification was sequence analysis of the D2 region of the 26S rRNA gene. In total, 823 isolates (96.6%) were identified to the genus level and 819 isolates (96.1%) were identified to the species level. Twenty-four isolates (2.8%) were not identified, and five isolates (0.6%) were misidentified. Misidentified isolates included one isolate of C. albicans (n = 58) identified as Candida dubliniensis, one isolate of Candida parapsilosis (n = 73) identified as Candida pelliculosa, and three isolates of Geotrichum klebahnii (n = 6) identified as Geotrichum candidum. The identification of clinically relevant yeasts using MS is superior to the phenotypic identification systems currently employed in clinical microbiology laboratories
Surfactant protein D inhibits HIV-1 infection of target cells via interference with gp120-CD4 interaction and modulates pro-inflammatory cytokine production
© 2014 Pandit et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Surfactant Protein SP-D, a member of the collectin family, is a pattern recognition protein, secreted by mucosal epithelial cells and has an important role in innate immunity against various pathogens. In this study, we confirm that native human SP-D and a recombinant fragment of human SP-D (rhSP-D) bind to gp120 of HIV-1 and significantly inhibit viral replication in vitro in a calcium and dose-dependent manner. We show, for the first time, that SP-D and rhSP-D act as potent inhibitors of HIV-1 entry in to target cells and block the interaction between CD4 and gp120 in a dose-dependent manner. The rhSP-D-mediated inhibition of viral replication was examined using three clinical isolates of HIV-1 and three target cells: Jurkat T cells, U937 monocytic cells and PBMCs. HIV-1 induced cytokine storm in the three target cells was significantly suppressed by rhSP-D. Phosphorylation of key kinases p38, Erk1/2 and AKT, which contribute to HIV-1 induced immune activation, was significantly reduced in vitro in the presence of rhSP-D. Notably, anti-HIV-1 activity of rhSP-D was retained in the presence of biological fluids such as cervico-vaginal lavage and seminal plasma. Our study illustrates the multi-faceted role of human SPD against HIV-1 and potential of rhSP-D for immunotherapy to inhibit viral entry and immune activation in acute HIV infection. © 2014 Pandit et al.The work (Project no. 2011-16850) was supported by Medical Innovation Fund of Indian Council of Medical Research, New Delhi, India (www.icmr.nic.in/)
Wide-Angle Seismic Imaging of Two Modes of Crustal Accretion in Mature Atlantic Ocean Crust
We present a highâresolution 2âD Pâwave velocity model from a 225âkmâlong active seismic profile, collected over ~60â75 Ma central Atlantic crust. The profile crosses five ridge segments separated by a transform and three nontransform offsets. All ridge discontinuities share similar primary characteristics, independent of the offset. We identify two types of crustal segment. The first displays a classic twoâlayer velocity structure with a high gradient Layer 2 (~0.9 s) above a lower gradient Layer 3 (0.2 s). Here, PmP coincides with the 7.5 km s contour, and velocity increases to >7.8 km s within 1 km below. We interpret these segments as magmatically robust, with PmP representing a petrological boundary between crust and mantle. The second has a reduced contrast in velocity gradient between the upper and lower crust and PmP shallower than the 7.5 km s contour. We interpret these segments as tectonically dominated, with PmP representing a serpentinized (alteration) front. While velocityâdepth profiles fit within previous envelopes for slowâspreading crust, our results suggest that such generalizations give a misleading impression of uniformity. We estimate that the two crustal styles are present in equal proportions on the floor of the Atlantic. Within two tectonically dominated segments, we make the first wideâangle seismic identifications of buried oceanic core complexes in mature (>20 Ma) Atlantic Ocean crust. They have a ~20âkmâwide âdomalâ morphology with shallow basement and increased upper crustal velocities. We interpret their midcrustal seismic velocity inversions as alteration and rockâtype assemblage contrasts across crustalâscale detachment faults
Multicenter evaluation of the vitek MS matrix-assisted laser desorption ionization-time of flight mass spectrometry system for identification of gram-positive aerobic bacteria
Matrix-assisted laser desorption ionizationâtime of flight mass spectrometry (MALDI-TOF) is gaining momentum as a tool for bacterial identification in the clinical microbiology laboratory. Compared with conventional methods, this technology can more readily and conveniently identify a wide range of organisms. Here, we report the findings from a multicenter study to evaluate the Vitek MS v2.0 system (bioMĂ©rieux, Inc.) for the identification of aerobic Gram-positive bacteria. A total of 1,146 unique isolates, representing 13 genera and 42 species, were analyzed, and results were compared to those obtained by nucleic acid sequence-based identification as the reference method. For 1,063 of 1,146 isolates (92.8%), the Vitek MS provided a single identification that was accurate to the species level. For an additional 31 isolates (2.7%), multiple possible identifications were provided, all correct at the genus level. Mixed-genus or single-choice incorrect identifications were provided for 18 isolates (1.6%). Although no identification was obtained for 33 isolates (2.9%), there was no specific bacterial species for which the Vitek MS consistently failed to provide identification. In a subset of 463 isolates representing commonly encountered important pathogens, 95% were accurately identified to the species level and there were no misidentifications. Also, in all but one instance, the Vitek MS correctly differentiated Streptococcus pneumoniae from other viridans group streptococci. The findings demonstrate that the Vitek MS system is highly accurate for the identification of Gram-positive aerobic bacteria in the clinical laboratory setting
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