148 research outputs found

    BUSINESS INTELLIGENCE PER INTERNET SERVICE PROVIDER IL CASO DI STUDIO CWNET S.R.L.

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    Il progetto, realizzato durante un tirocinio di 6 mesi presso CWNet s.r.l, Internet Service Provider, mira alla creazione di un sistema informativo capace di fornire strumenti per il miglioramento delle performance aziendali. Il raggiungimento dell'obiettivo ha richiesto lo svolgimento di un processo di Business Intelligence, grazie al quale, partendo da un'analisi accurata del core business, del portafoglio prodotti e degli accessi al sito web, è stato possibile scoprire informazioni e suggerimenti utili per il management. Le tecnologie adoperate per svolgere questo progetto hanno fatto leva sulle tecniche di data warehousing, data mining e web usage mining. Il presente lavoro di tesi introduce brevemente la storia di internet e tratta dei principali cambiamenti sociali e comportamentali da esso derivanti. La presenza di ulteriori mutamenti possibili dovuti all'introduzione di internet, ha reso necessaria la trattazione delle Business intelligence, della quale sono stati esposti ruolo e metodologie. La tesi presenta inoltre il contesto aziendale in cui il lavoro è stato svolto e gli strumenti adoperati per il raggiungimento dell'obiettivo preposto. I casi in esame e i risultati ritenuti più interessanti al fine del raggiungimento dell'obiettivo sono stati riportati con le opportune considerazioni

    Mean Transit Time Across the Capillary Membrane for Different Weights of FITC-Dextran

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    A multilevel analysis of craniofacial growth in subjects with untreated Class III malocclusion

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    ObjectiveTo analyse the craniofacial growth of a long‐term semi‐longitudinal sample of Caucasian subjects with untreated Class III malocclusion.Setting and sample populationA total of 144 Caucasian subjects (of North American and Italian origin) with untreated Class III malocclusion. Materials and methodsSubjects aged 2 years and 9 months up to 21 years and 7 months were selected. A multilevel model was used to calculate growth curves for ten variables for both each individual subject and for the whole sample.ResultsThere was a statistically significant increase for total mandibular length (Co‐Gn. T2‐T1 = 8.4 mm), midfacial length (Co‐A. T2‐T1 = 3.4 mm) and lower anterior facial height (ANS‐Me. T2‐T1 = 3.8 mm). The multilevel analysis showed two points of acceleration of growth (about 3‐5 years of age and 11‐15 years of age) for seven out of ten variables. For Co‐Gn and Co‐A variables, males presented points of maximum growth delayed by 1 year in comparison with females, with a greater duration (1 year longer) and a greater total growth of about 5 mm. Active mandibular growth continued for a long time after the pubertal spurt: increases in mandibular length ended at about 17 years of age in females and at 21 years and 7 months in males.ConclusionsUntreated Class III malocclusion showed a specific growth curve, especially for the mandible, whose excesses added up over time. In males, the amounts of mandibular and midfacial growth during the whole observation time were greater and lasted longer than in females.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/154906/1/ocr12356.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/154906/2/ocr12356_am.pd

    In planta production of two peptides of the Classical Swine Fever Virus (CSFV) E2 glycoprotein fused to the coat protein of potato virus X

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    BACKGROUND: Classical Swine Fever (CSFV) is one of the most important viral infectious diseases affecting wild boars and domestic pigs. The etiological agent of the disease is the CSF virus, a single stranded RNA virus belonging to the family Flaviviridae. All preventive measures in domestic pigs have been focused in interrupting the chain of infection and in avoiding the spread of CSFV within wild boars as well as interrupting transmission from wild boars to domestic pigs. The use of plant based vaccine against CSFV would be advantageous as plant organs can be distributed without the need of particular treatments such as refrigeration and therefore large areas, populated by wild animals, could be easily covered. RESULTS: We report the in planta production of peptides of the classical swine fever (CSF) E2 glycoprotein fused to the coat protein of potato virus X. RT-PCR studies demonstrated that the peptide encoding sequences are correctly retained in the PVX construct after three sequential passage in Nicotiana benthamiana plants. Sequence analysis of RT-PCR products confirmed that the epitope coding sequences are replicated with high fidelity during PVX infection. Partially purified virions were able to induce an immune response in rabbits. CONCLUSION: Previous reports have demonstrated that E2 synthetic peptides can efficiently induce an immunoprotective response in immunogenized animals. In this work we have showed that E2 peptides can be expressed in planta by using a modified PVX vector. These results are particularly promising for designing strategies for disease containment in areas inhabited by wild boars

    Protective effects of a gastrointestinal agent containing Korean red ginseng on gastric ulcer models in mice

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    <p>Abstract</p> <p>Background</p> <p>Korean red ginseng (KRG) is a ginseng that has been cultivated and aged for 4-6 years or more, and goes through an extensive cleaning, steaming and drying process. KRG contains more than 30 kinds of saponin components and has been reported as having various biological properties, such as anti-fatigue action, immune restoration, and neurovegetative effect. The purpose of this study was to assess the effects of a KRG-containing drug (KRGCD) on gastric ulcer models in mice.</p> <p>Methods</p> <p>Stomach ulcers were induced by oral ingestion of hydrochloride (HCl)/ethanol or indomethacin. Treatment with KRGCD (30, 100, and 300 mg/kg, p.o.) occurred 1 hr before the ulcer induction. Effect of KRGCD on anti-oxidant activity and gastric mucosal blood flow with a laser Doppler flowmeter in mice stomach tissue was evaluated.</p> <p>Results</p> <p>KRGCD (100 and 300 mg/kg, p.o.) significantly decreased ethanol- and indomethacin-induced gastric ulcer compared with the vehicle-treated (control) group. KRGCD (100 and 300 mg/kg) also decreased the level of thiobarbituric acid reactive substance (TBARS) and increased gastric mucosal blood flow compared with the control group.</p> <p>Conclusions</p> <p>These results suggest that the gastroprotective effects of KRGCD on mice ulcer models can be attributed to its ameliorating effect on oxidative damage and improving effect of gastric mucosal blood flow.</p

    Analisi e miglioramento dei processi in Barsanti Macchine S.p.A.

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    La presente tesi, basata sull'attività di tirocinio in Barsanti Macchine S.p.A., ha voluto evidenziare i gap emersi durante l'analisi dei processi in riferimento alla norma Iso 9001:2000 e le proposte di miglioramento intraprese per colmarle. I risultati ottenuti sono stati l’individuazione delle criticità e il ranking delle stesse che hanno determinato un approccio teso alla risoluzione di quelle con criticità maggiore. Si è dunque redatto le procedure (istruzioni operative) per il reparto produttivo; si sono predisposte le azioni di verifica e controllo delle forniture; si è proposta una procedura che rendesse sistematici i controlli in produzione per le tipologie di prodotti analizzati; dandone evidenza e potendo garantirne la rintracciabilità; si è collaborato allo sviluppo del sistema di tracciabilità in logistica; con l’ausilio di MS Access, si è elaborato un programma che consentisse di effettuare le registrazioni delle attività di controllo e di taratura; infine si è cercato di intensificazione le attività di monitoraggio e misurazione sistematiche del processo tramite la redazione di indici di processo facilmente calcolabili
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