6 research outputs found

    Sand flea (Tunga spp.) infections in humans and domestic animals: state of the art.

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    Tungiasis is a parasitic disease of humans and animals caused by fleas (Siphonaptera) belonging to the genus Tunga. Two species, Tunga penetrans (L.) and Tunga trimamillata, out of 10 described to date, are known to affect man or domestic animals; the other eight are exclusive to a few species of wild mammals. Tunga penetrans and T. trimamillata originated from Latin America, although the first species is also found in sub-Saharan Africa (between 20\u25e6 N and 25\u25e6 S). Hundreds of millions of people are at risk of infection in more than 70 nations, mostly in developing countries. The second species has been reported only in Ecuador and Peru. Males and non-fertilized females of Tunga are haematophagous ectoparasites; pregnant females penetrate the skin where, following dilatation of the abdomen, they increase enormously in size (neosomy) and cause inflammatory and ulcerative processes of varying severity. The importance of Tunga infection in humans concerns its frequent localization in the foot, which sometimes causes very serious difficulty in walking, thereby reducing the subject\u2019s ability to work and necessitating medical and surgical intervention. Tungiasis in domestic animals can be responsible for economic losses resulting from flea-induced lesions and secondary infections. Because tungiasis represents a serious problem for tropical public health and because of the recent description of a new species (Tunga trimamillata), it seems appropriate to review current knowledge of the morphology, molecular taxonomy, epidemiology, pathology, treatment and control of sand fleas of the genus Tunga

    Actor-networking the ‘failed state’ — an enquiry into the life of concepts

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    Concepts such as the ‘failed state’ are jointly produced by academics and political actors and hence connect academia and global politics. Little attention has been spent to study such concepts and the practices that create them and sustain their relevance. We develop an innovative framework for studying concepts. Relying on actor-network theory, we suggest studying concepts as effects of relations between different actors building an actor-network. We introduce actor-network theory and demonstrate its value for international relations (IR) research. Our empirical case study of the concept of failed states combines bibliometric analysis and qualitative text analysis. We show how various actors have brought the concept of failed states to life; analyse how actors transformed because of their participation; and investigate the persistent struggles to define and homogenise the concept. In summary, this is an article about the life of the failed state, the discipline of IR and its relations to other actors, and an introduction of the actor-network theory toolbox to the sociology of IR

    Peripheral Nerve Injury Modulates Neurotrophin Signaling in the Peripheral and Central Nervous System

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