The Effect of Auditor Knowledge Utilization in a Task on Observer Assessments of the Effect of Task Experience on Expert Potential

The study of expertise and expert-development has been and continues to be a major focus of auditing behavioral research. This paper furthers studies of the evolution of auditor expertise by augmenting Russo\u27s model of learning and expert-like behavior during performance of a field task to include observer assessments of the effect of the current task experience on an auditor\u27s potential for expert development in the future

Yang-Mills Duals for Semiclassical Strings

We consider a semiclassical multiwrapped circular string pulsating on S_5, whose center of mass has angular momentum J on an S_3 subspace. Using the AdS/CFT correspondence we argue that the one-loop anomalous dimension of the dual operator is a simple rational function of J/L, where J is the R-charge and L is the bare dimension of the operator. We then reproduce this result directly from a super Yang-Mills computation, where we make use of the integrability of the one-loop system to set up an integral equation that we solve. We then verify the results of Frolov and Tseytlin for circular rotating strings with R-charge assignment (J',J',J). In this case we solve for an integral equation found in the O(-1) matrix model when J' J. The latter region starts at J'=L/2 and continues down, but an apparent critical point is reached at J'=4J. We argue that the critical point is just an artifact of the Bethe ansatz and that the conserved charges of the underlying integrable model are analytic for all J' and that the results from the O(-1) model continue onto the results of the O(+1) model.Comment: 26 Pages, LaTeX; v2 Typos corrected, reference update

Hormonal control of p53 and chemoprevention

Improvements in the detection and treatment of breast cancer have dramatically altered its clinical course and outcome. However, prevention of breast cancer remains an elusive goal. Parity, age of menarche, and age at menopause are major risk factors drawing attention to the important role of the endocrine system in determining the risk of breast cancer, while heritable breast cancer susceptibility syndromes have implicated tumor suppressor genes as important targets. Recent work demonstrating hormonal modulation of the p53 tumor suppressor pathway draws together these established determinants of risk to provide a model of developmental susceptibility to breast cancer. In this model, the mammary epithelium is rendered susceptible due to impaired p53 activity during specific periods of mammary gland development, but specific endocrine stimuli serve to activate p53 function and to mitigate this risk. The results focus attention on p53 as a molecular target for therapies to reduce the risk of breast cancer