UV to radio centimetric spectral energy distributions of optically-selected late-type galaxies in the Virgo cluster

We present a multifrequency dataset for an optically-selected, volume-limited, complete sample of 118 late-type galaxies (>= S0a) in the Virgo cluster. The database includes UV, visible, near-IR, mid-IR, far-IR, radio continuum photometric data as well as spectroscopic data of Halpha, CO and HI lines, homogeneously reduced, obtained from our own observations or compiled from the literature. Assuming the energy balance between the absorbed stellar light and that radiated in the IR by dust, we calibarte an empirical attenuation law suitable for correcting photometric and spectroscopic data of normal galaxies. The data, corrected for internal extinction, are used to construct the spectral energy distribution (SED) of each individual galaxy, and combined to trace the median SED of galaxies in various classes of morphological type and luminosity. Low-luminosity, dwarf galaxies have on average bluer stellar continua and higher far-IR luminosities per unit galaxy mass than giant, early-type spirals. If compared to nearby starburst galaxies such as M82 and Arp 220, normal spirals have relatively similar observed stellar spectra but 10-100 times lower IR luminosities. The temperature of the cold dust component increases with the far-IR luminosity, from giant spirals to dwarf irregulars. The SED are used to separate the stellar emission from the dust emission in the mid-IR regime. We show that the contribution of the stellar emission at 6.75 micron to the total emission of galaxies is generally important, from ~ 80% in Sa to ~ 20% in Sc.Comment: 31 pages, 12 figures, 12 tables. Fig 2 avaliable at (http://goldmine.mib.infn.it/papers/isosed.html). Accepted for publication on A&

Rejuvenating conventional dendritic cells and T follicular helper cell formation after vaccination.

Germinal centres (GCs) are T follicular helper cell (Tfh)-dependent structures that form in response to vaccination, producing long-lived antibody secreting plasma cells and memory B cells that protect against subsequent infection. With advancing age the GC and Tfh cell response declines, resulting in impaired humoral immunity. We sought to discover what underpins the poor Tfh cell response in ageing and whether it is possible to correct it. Here, we demonstrate that older people and aged mice have impaired Tfh cell differentiation upon vaccination. This deficit is preceded by poor activation of conventional dendritic cells type 2 (cDC2) due to reduced type 1 interferon signalling. Importantly, the Tfh and cDC2 cell response can be boosted in aged mice by treatment with a TLR7 agonist. This demonstrates that age-associated defects in the cDC2 and Tfh cell response are not irreversible and can be enhanced to improve vaccine responses in older individuals

Turtles outsmart rapid environmental change: The role of cognition in navigation.

Animals inhabiting changing environments show high levels of cognitive plasticity. Cognition may be a means by which animals buffer the impact of environmental change. However, studies examining the evolution of cognition seldom compare populations where change is rapid and selection pressures are strong. We investigated this phenomenon by radiotracking experienced and naïve Eastern painted turtles (Chrysemys picta) as they sought new habitats when their pond was drained. Resident adults repeatedly used specific routes to permanent water sources with exceptional precision, while adults translocated to the site did not. Naïve 1-3 y olds from both populations used the paths taken by resident adults, an ability lost by age 4. Experience did not, however, influence the timing of movement or the latency to begin navigation. This suggests that learning during a critical period may be important for how animals respond to changing environments, highlighting the importance of incorporating cognition into conservation

Turtles outsmart rapid environmental change: The role of cognition in navigation

Animals inhabiting changing environments show high levels of cognitive plasticity. Cognition may be a means by which animals buffer the impact of environmental change. However, studies examining the evolution of cognition seldom compare populations where change is rapid and selection pressures are strong. We investigated this phenomenon by radiotracking experienced and naïve Eastern painted turtles (Chrysemys picta) as they sought new habitats when their pond was drained. Resident adults repeatedly used specific routes to permanent water sources with exceptional precision, while adults translocated to the site did not. Naïve 1–3 y olds from both populations used the paths taken by resident adults, an ability lost by age 4. Experience did not, however, influence the timing of movement or the latency to begin navigation. This suggests that learning during a critical period may be important for how animals respond to changing environments, highlighting the importance of incorporating cognition into conservation

Using Pharmacological Manipulation and High-precision Radio Telemetry to Study the Spatial Cognition in Free-ranging Animals.

An animal\u27s ability to perceive and learn about its environment plays a key role in many behavioral processes, including navigation, migration, dispersal and foraging. However, the understanding of the role of cognition in the development of navigation strategies and the mechanisms underlying these strategies is limited by the methodological difficulties involved in monitoring, manipulating the cognition of, and tracking wild animals. This study describes a protocol for addressing the role of cognition in navigation that combines pharmacological manipulation of behavior with high-precision radio telemetry. The approach uses scopolamine, a muscarinic acetylcholine receptor antagonist, to manipulate cognitive spatial abilities. Treated animals are then monitored with high frequency and high spatial resolution via remote triangulation. This protocol was applied within a population of Eastern painted turtles (Chrysemys picta) that has inhabited seasonally ephemeral water sources for ~100 years, moving between far-off sources using precise (± 3.5 m), complex (i.e., non-linear with high tortuosity that traverse multiple habitats), and predictable routes learned before 4 years of age. This study showed that the processes used by these turtles are consistent with spatial memory formation and recall. Together, these results are consistent with a role of spatial cognition in complex navigation and highlight the integration of ecological and pharmacological techniques in the study of cognition and navigation