5 research outputs found
Telomerase-pulsed dendritic cells: preclinical results and outcome of a clinical phase I/II trial in patients with metastatic renal cell carcinoma
Objective: Therapeutic vaccination with dendritic cells (DC) showed promising results in first clinical trials in cases of metastatic renal cell carcinoma (RCC). Human telomerase reverse transcriptase (hTERT) could be a potential target because it is detectable in more than 85% of human tumors including RCC
Characterization of the demonstrator of the fast silicon monolithic ASIC for the TT-PET project
The TT-PET collaboration is developing a small animal TOF-PET scanner based
on monolithic silicon pixel sensors in SiGe BiCMOS technology. The demonstrator
chip, a small-scale version of the final detector ASIC, consists of a 3 x 10
pixel matrix integrated with the front-end, a 50 ps binning TDC and read out
logic. The chip, thinned down to 100 {\mu}m and backside metallized, was
operated at a voltage of 180 V. The tests on a beam line of minimum ionizing
particles show a detection efficiency greater than 99.9 % and a time resolution
down to 110 ps