An osteological and historical examination of the Presbyterian Forest Centre Cemetery, Prince Albert, Saskatchewan

On October 7th, 2004, construction of the Saskatchewan Forest Centre Building in Prince Albert, Saskatchewan was temporarily halted due to the exposure of human remains from within the soil matrix. Subsequent archaeological investigation revealed the presence of numerous rectangular soil stains suggesting the presence of additional interments within the construction site. The remains of two individuals were recovered during this original construction exposure. The following spring, Western Heritage Services, Inc., in coordination with the Department of Archaeology, University of Saskatchewan, conducted an extensive excavation at the site which unearthed 19 individuals of different racial affiliation, sex, and age. Interment location and an extensive document and literature review suggest that this was the cemetery established by Rev. James Nisbet, founder of the Prince Albert mission. This mission would evolve into the City of Prince Albert. The historic significance and sensitive nature of the site required the involvement of several interest groups including the Heritage Resource Branch of the Department of Saskatchewan Culture, Youth and Recreation, the Prince Albert Historical Society, and above all, St. Paul’s Presbyterian Church which was responsible for the reinterment of the Forest Centre individuals and was an indispensable source of information. Prior to reinterment, a fundamental osteological and paleopathological examination was conducted for each of the 21 individuals. Coordination and completion of cultural material analysis was performed by Amanda Boechler, an undergraduate archaeology student of the University of Saskatchewan and Mark MacKenzie of the Western Development Museum. Preliminary results may be found within the final site report issued by Western Heritage Services, Inc. dated November, 2005

Concert recording 2019-11-11

[Track 1]. Quia respexit from Magnificat / Johann Sebastian Bach -- [Track 2]. An Chloe / Wolfgang Amadeus Mozart -- [Track 3]. Auf dem Wasser zu singen / Franz Schubert -- [Track 4]. Le spectre de la rose / Hector Berlioz -- [Track 5]. Mandoline / Gabriel Faure -- [Track 6]. I carry your heart / John Duke -- [Track 7]. Love\u27s philosophy / Roger Quilter -- [Track 8]. Les oiseaux dans la charmille from Les contes d\u27Hoffmann / Jacques Offenbach

Impact of the 13-valent pneumococcal conjugate vaccine (pcv13) on invasive pneumococcal disease and carriage in Alaska

AbstractBackgroundAlaska Native (AN) children have experienced high rates of invasive pneumococcal disease (IPD). In March 2010, PCV13 was introduced statewide in Alaska. We evaluated the impact of PCV13 on IPD in children and adults, 45 months after introduction.MethodsPneumococcal sterile site isolates, reported through state-wide surveillance, were serotyped using standard methods. We defined a pre-PCV13 time period 2005–2008 and post-PCV13 time period April 2010–December 2013; excluding Jan 2009–March 2010 because PCV13 was introduced pre-licensure in one high-risk region in 2009.ResultsAmong Alaska children <5 years, PCV13 serotypes comprised 65% of IPD in the pre-PCV13 period and 26% in the PCV13 period. Among all Alaska children <5 years, IPD rates decreased from 60.9 (pre) to 25.4 (post) per 100,000/year (P<0.001); PCV13 serotype IPD decreased from 37.7 to 6.4 (P<0.001). Among AN children <5 years, IPD rates decreased from 149.2 to 60.8 (P<0.001); PCV13 serotype IPD decreased from 87.0 to 17.4 (P<0.001); non-PCV13 serotype IPD did not change significantly. Among persons 5–17 and ≥45 years, the post-vaccine IPD rate was similar to the baseline period, but declined in persons 18–44 years (39%, P<0.001); this decline was similar in AN and non-AN persons (38%, P=0.016, 43%, P=0.014, respectively).ConclusionsForty-five months after PCV13 introduction, overall IPD and PCV13-serotype IPD rates had decreased 58% and 83%, respectively, in Alaska children <5 years of age when compared with 2005–2008. We observed evidence of indirect effect among adults with a 39% reduction in IPD among persons 18–44 years

Early Neuromuscular Blockade in Moderate-to-Severe Pediatric Acute Respiratory Distress Syndrome

Objectives: The use of neuromuscular blocking agents (NMBAs) in pediatric acute respiratory distress syndrome (PARDS) is common but unsupported by efficacy data. We sought to compare the outcomes between patients with moderate-to-severe PARDS receiving continuous NMBA during the first 48 hours of endotracheal intubation (early NMBA) and those without. Design: Secondary analysis of data from the Randomized Evaluation of Sedation Titration for Respiratory Failure (RESTORE) clinical trial, a pediatric multicenter cluster randomized trial of sedation. Setting: Thirty-one PICUs in the United States. Patients: Children 2 weeks to 17 years receiving invasive mechanical ventilation (MV) for moderate-to-severe PARDS (i.e., oxygenation index >= 8 and bilateral infiltrates on chest radiograph on days 0-1 of endotracheal intubation). Interventions: NMBA for the entire duration of days 1 and 2 after intubation. Measurements and Main Results: Among 1,182 RESTORE patients with moderate-to-severe PARDS, 196 (17%) received early NMBA for a median of 50.0% ventilator days (interquartile range, 33.3-60.7%). The propensity score model predicting the probability of receiving early NMBA included high-frequency oscillatory ventilation on days 0-2 (odds ratio [OR], 7.61; 95% CI, 4.75-12.21) and severe PARDS on days 0-1 (OR, 2.16; 95% CI, 1.50-3.12). After adjusting for risk category, early use of NMBA was associated with a longer duration of MV (hazard ratio, 0.57; 95% CI, 0.48-0.68; p < 0.0001), but not with mortality (OR, 1.62; 95% CI, 0.92-2.85; p = 0.096) compared with no early use of NMBA. Other outcomes including cognitive, functional, and physical impairment at 6 months post-PICU discharge were similar. Outcomes did not differ when comparing high versus low NMBA usage sites or when patients were stratified by baseline PaO2/FIO2 less than 150. Conclusions: Early NMBA use was associated with a longer duration of MV. This propensity score analysis underscores the need for a randomized controlled trial in pediatrics

Lifetime Traumatic Brain injury and Risk of Post-Concussive Symptoms in the Millennium Cohort Study

Traumatic brain injury (TBI) is prevalent among active duty military service members, with studies reporting up to 23% experiencing at least one TBI, with 10-60% of service members reporting at least one subsequent repeat TBI. A TBI has been associated with an increased risk of cumulative effects and long-term neurobehavioral symptoms, impacting operational readiness in the short-term and overall health in the long term. The association between multiple TBI and post-concussive symptoms (PCS), however, defined as symptoms that follow a concussion or TBI, in the military has not been adequately examined. Previous studies in military populations are limited by methodological issues including small sample sizes, the use of non-probability sampling, or failure to include the total number of TBI. to overcome these limitations, we examined the association between the total lifetime number of TBI and total number of PCS among U.S. active duty military service members who participated in the Millennium Cohort Study. A secondary data analysis was conducted using the Millennium Cohort Study\u27s 2014 survey

Occupation and Risk of Traumatic Brain injury in the Millennium Cohort Study

INTRODUCTION: Traumatic brain injury (TBI) is an occupational health hazard of military service. Few studies have examined differences in military occupational categories (MOC) which take into consideration the physical demands and job requirements across occupational groups. METHODS: This study was approved by the University of Texas Health Science Center at Houston Institutional Review Board. Data for this cross-sectional study were obtained from the Naval Health Research Center\u27s Millennium Cohort Study, an ongoing DoD study. Univariate analyses were employed to calculate frequencies and proportions for all variables. Bivariate analyses included unadjusted odds ratios (OR) and 95% CI for the association between all variables and TBI. Multivariable logistic regression was used to calculate adjusted ORs and 95% CIs to assess the association between MOC and TBI, adjusted for potential confounders: sex, race/ethnicity, rank, military status, branch of service, before-service TBI, and panel. Logistic regression models estimated odds of TBI for each MOC, and stratified models estimated odds separately for enlisted and officer MOCs. RESULTS: Approximately 27% of all participants reported experiencing a service-related TBI. All MOCs were statistically significantly associated with increased odds of service-related TBI, with a range of 16 to 45%, except for Health Care MOCs (OR: 1.01, 95% CI 0.91-1.13). Service members in Infantry/Tactical Operations had the highest odds (OR: 1.45, 95% CI 1.31-1.61) of service-related TBI as compared to Administration & Executives. Among enlisted service members, approximately 28% reported experiencing a service-related TBI. Among enlisted-specific MOCs, the odds of TBI were elevated for those serving in Infantry, Gun Crews, Seamanship (OR: 1.79, 95% CI 1.58-2.02), followed by Electrical/Mechanical Equipment Repairers (OR: 1.23, 95% CI 1.09-1.38), Service & Supply Handlers (OR 1.21, 95% CI 1.08-1.37), Other Technical & Allied Specialists (OR 1.21, 95% CI 1.02-1.43), Health Care Specialists (OR 1.19, 95% CI 1.04-1.36), and Communications & Intelligence (OR: 1.16, 95% CI 1.02-1.31), compared to Functional Support & Administration. Among officer service members, approximately 24% reported experiencing a service-related TBI. After adjustment the odds of TBI were found to be significant for those serving as Health Care Officers (OR: 0.65, 95% CI: 0.52-0.80) and Intelligence Officers (OR: 1.27, 95% CI: 1.01-1.61). CONCLUSIONS: A strength of this analysis is the breakdown of MOC associations with TBI stratified by enlisted and officer ranks, which has been previously unreported. Given the significantly increased odds of service-related TBI reporting within enlisted ranks, further exploration into the location (deployed versus non-deployed) and mechanism (e.g., blast, training, sports, etc.) for these injuries is needed. Understanding injury patterns within these military occupations is necessary to increase TBI identification, treatment, and foremost, prevention.Results highlight the importance of examining specific occupational categories rather than relying on gross categorizations, which do not account for shared knowledge, skills, and abilities within occupations. The quantification of risk among enlisted MOCs suggests a need for further research into the causes of TBI

Concert recording 2019-11-25

[Track 1]. Come paride vezzozo from L\u27elisir d\u27amore / Gaetano Donizetti -- [Track 2]. Apparition / Claude Debussy -- [Track 3]. Ebben, nandro lontana from La Wally / Alfredo Catalani -- [Track 4]. Lamento di Federico from L\u27Arlesiana / Francesco Cilea -- [Track 5]. My man\u27s gone now from Porgy and Bess / George Gershwin -- [Track 6]. I carry you heart / John Duke -- [Track 7]. Les oiseaux dans la charmille from Les contes d\u27Hoffmann / Jacques Offenbach -- [Track 8]. La serenata [Track 9]. Penso [Track 10]. Tristezza / Francesco Paolo Tosti -- [Track 11]. Three Browning songs, op. 44. The year\u27s at the spring [Track 12]. Ah! Love, but a day! [Track 13]. I send my heart up to Thee / Amy Beach

Concert recording 2018-10-29

[Track 1]. The wolf\u27s aria from Little red riding hood / Seymour Barab -- [Track 2]. Die beiden Grenadiene / Robert Schumann -- [Track 3]. Jeanie with the light brown hair / Stephen Foster -- [Track 4]. Verborgenheit / Hugo Wolf -- [Track 5]. Ridente la calma / Wolfgang Amadeus Mozart -- [Track 6]. Allerseelen / Richard Strauss -- [Track 7]. Laurie\u27s song from The tender land / Aaron Copland -- [Track 8]. Come raggio di sol / Antonio Caldara -- [Track 9]. Gretchen am Spinnrade / Franz Schubert -- [Track 10]. La Spectre de la Rose from Les Nuits d\u27Ete / Hector Berlioz -- [Track 11]. Lied der Mignon / Franz Schubert -- [Track 12]. This is my beloved from Kismet / Robert Wright George Forrest -- [Track 13]. Dein blaues Auge [Track 14]. Wie Melodien zieht es / Johannes Brahms -- [Track 15]. The infinite shining heavens from Songs of travel / Ralph Vaughan-Williams -- [Track 16]. O stay, my love / Sergei Rachmaninoff -- [Track 17]. Il lacerato spirito from Simon Boccanegra / Giuseppe Verdi -- [Track 18]. There but for you I go from Brigadoon / Lerner and Loewe

Concert recording 2019-10-27

[Track 1]. Now sleeps the crimson petal / Roger Quilter -- [Track 2]. Ideale / Paolo Tosti -- [Track 3]. Intorno all\u27idol mio / Anthony Cesti -- [Track 4]. Chanson triste / Henri Duparc -- [Track 5]. Son tutta duolol / Alessandro Scarlatti -- [Track 6]. Aprile / P. Tosti -- [Track 7]. Ah, love, but a day! / Amy Beach -- [Track 8]. So shall the lute and harp awake from An Oratorio-Judas Maccebaeus / George Frideric Handel -- [Track 9]. Come again / John Dowland -- [Track 10]. Der kuss / Ludwig van Beethoven -- [Track 11]. An Chloe / W. A. Mozart -- [Track 12]. Auf dem Wasser zu singen / Franz Schubert --[Track 13]. Allerseelen / Richard Strauss -- [Track 14]. I never saw another butterfly. II. Yes, that\u27s the way things are ; [Track 15]. III. Birdsong / Lori Laitman -- [Track 16]. Je dis que rien m\u27epouvante from Carmen / Georges Bizet -- [Track 17]. Che gelinda manina from La Boheme / Giacomo Puccini -- [Track 18]. Kristine Mezines, piano Granada / Agustin Lara -- [Track 19]. My name from Eve-Song / Jake Heggie -- [Track 20]. Do not go, my love / Richard Hageman