722 research outputs found
Surface flow profiles for dry and wet granular materials by Particle Tracking Velocimetry; the effect of wall roughness
Two-dimensional Particle Tracking Velocimetry (PTV) is a promising technique
to study the behaviour of granular flows. The aim is to experimentally
determine the free surface width and position of the shear band from the
velocity profile to validate simulations in a split-bottom shear cell geometry.
The position and velocities of scattered tracer particles are tracked as they
move with the bulk flow by analyzing images. We then use a new technique to
extract the continuum velocity field, applying coarse-graining with the
postprocessing toolbox MercuryCG on the discrete experimental PTV data. For
intermediate filling heights, the dependence of the shear (or angular) velocity
on the radial coordinate at the free surface is well fitted by an error
function. From the error function, we get the width and the centre position of
the shear band. We investigate the dependence of these shear band properties on
filling height and rotation frequencies of the shear cell for dry glass beads
for rough and smooth wall surfaces. For rough surfaces, the data agrees with
the existing experimental results and theoretical scaling predictions. For
smooth surfaces, particle-wall slippage is significant and the data deviates
from the predictions. We further study the effect of cohesion on the shear band
properties by using small amount of silicon oil and glycerol as interstitial
liquids with the glass beads. While silicon oil does not lead to big changes,
glycerol changes the shear band properties considerably. The shear band gets
wider and is situated further inward with increasing liquid saturation, due to
the correspondingly increasing trend of particles to stick together
Evolutionary Models for Formation of Network Motifs and Modularity in the Saccharomyces Transcription Factor Network
Many natural and artificial networks contain overrepresented subgraphs, which have been termed network motifs. In this article, we investigate the processes that led to the formation of the two most common network motifs in eukaryote transcription factor networks: the bi-fan motif and the feed-forward loop. Around 100 million y ago, the common ancestor of the Saccharomyces clade underwent a whole-genome duplication event. The simultaneous duplication of the genes created by this event enabled the origin of many network motifs to be established. The data suggest that there are two primary mechanisms that are involved in motif formation. The first mechanism, enabled by the substantial plasticity in promoter regions, is rewiring of connections as a result of positive environmental selection. The second is duplication of transcription factors, which is also shown to be involved in the formation of intermediate-scale network modularity. These two evolutionary processes are complementary, with the pre-existence of network motifs enabling duplicated transcription factors to bind different targets despite structural constraints on their DNA-binding specificities. This process may facilitate the creation of novel expression states and the increases in regulatory complexity associated with higher eukaryotes
Feasibility Methodology for Multistory Buildings with Respect to Fallout Radiation Protection
Architectural Engineerin
A Combined Laboratory and Synchrotron In-Situ Photoemission Study of the Rutile TiO2 (110) / Water Interface
In-situ analysis of the TiO2 / water interface via NAP-XPS is demonstrated in both a lab based system (NAP-cell configuration) and synchrotron endstation (backfill configuration). Ultra-thin wetting layers (UTWL) of liquid water (~10 nm) are formed on a rutile TiO2 surface with minimal contamination present in addition to unique insight during the growth of the liquid films as indicated via NAP-XPS, in-situ sample temperature and background vapour pressure monitoring. Chemical changes at the solid / liquid interface are also demonstrated via healing of Ti3+ surface defect states. Photon depth profiling of the as grown liquid layers indicate that the formed films are ultra-thin (~10 nm) and likely to be continuous in nature. This work demonstrates a novel and flexible approach for studying the solid / liquid interface via NAP-XPS which is readily integrated with any form of NAP-XPS system, thereby making a critical interface of study available to a wide audience of researchers for use in operando electrochemical and photocatalytic research
Factors Influencing Emergency Contraception Use in Indigent Populations
Introduction: Indigent women are disproportionately affected by unwanted, unplanned pregnancies. Studies previously identified lack of knowledge about emergency contraception (EC) as a major deterrent from use. This study was performed to address three potential barriers to the use of EC in indigent populations: culture and religion, patient education, and cost. For the entirety of this study, EC refers to levonorgestrel (LNG).
Objectives: To determine the impact of culture and religion, patient education, and cost on EC use in the indigent population.
Methods: This study was a cross-sectional observational study to explore and investigate relationships between indigent populations and the use of EC. To be included in the study, participants had to be: at least 14 years old, female, and have an annual household income below the federal poverty line (FPL). Those excluded were less than 14 years old, male, and reported an annual household income above the FPL. A questionnaire consisting of 31 survey questions were utilized to assess the endpoints of the study. The study utilized both paper and electronic forms of the survey. Participants signed informed consent to enable them participate in the study. Out of 319 participants, 59 met all inclusion criteria and were used in statistical analyses.
Results:Based on Kruskal-Wallis results, religious groups’ acceptance of EC influenced indigent women’s decision to use it (p=0.016). Level of education also influenced women’s understanding of EC as an abortifacient and knowledge of when LNG is effective. Spearman rho revealed correlations between participants’ willingness to pay for EC or routine birth control and knowing that EC was an option (coefficient 0.391; p-value 0.005). There was also a correlation between the cost of EC and ultimate use (coefficient -0.603; p-value
Conclusion: Our research found that religious groups’ acceptance of EC use and knowledge about how LNG works does affect the decision to use EC. Neither cultural identification nor cost of EC appears to have a significant impact on the final decision to use
New deal for disabled people national extension: findings from the first wave of qualitative research with clients, job brokers and jobcentre plus staff
The New Deal for Disabled People (NDDP) was introduced in 1998 and 1999 as a series of pilots
designed to evaluate services based on the use of personal advisers to help disabled people move into
or stay in paid employment. The pilots were wound up in 2001 and superseded by what is known as
the ‘national extension’ of NDDP, the aim of which is to ‘support and test innovative ways of helping
people on Incapacity Benefits move from economic inactivity into sustained employment’ (DSS, ES,
DfEE research specification, April, 2001). Services under the national extension are provided by a
network of around 60 ‘Job Broker’ organisations including voluntary and other not-for-profit bodies,
commercial companies, government agencies and other public sector organisations. This report
presents findings from a first wave of qualitative research carried out in 2002 which forms part of a
larger programme of work aimed at providing the Department for Work and Pensions with a
comprehensive evaluation of the NDDP extension.
The overall aim of the qualitative research is to explore the organisation, operation and impacts of the
Job Broker service from the perspective of all key stakeholders, including users and providers of Job
Broker services, and staff of Jobcentre Plus offices. Specifically, the research was designed to
produce data on the following:
• factors affecting participation in the Job Broker programme
• clients’ understanding and experiences of NDDP
• the role and operation of Job Brokers
• the role and operation of the Jobcentre Plus staff who can provide people with information about
Job Broker services.
A research design was adopted that aimed to gather data using a range of qualitative research
techniques from key actors associated with 18 Job Broker services operating in 15 specific
geographical areas. The first wave of data collection was carried out in the Summer/Autumn of 2002;
a second wave is planned for 2003.
The report is organised into three main parts. Part I (Chapters 2 to 5) presents findings from the Job
Broker and Jobcentre Plus staff research. In Part II (Chapters 6 to 9), the client perspective is
presented. Part III (Chapter 10) provides an overall summary of the emerging issues
Performance of bulk SiC radiation detectors
SiC is a wide-gap material with excellent electrical and physical properties that may make it an important material for some future electronic devices. The most important possible applications of SiC are in hostile environments, such as in car/jet engines, within nuclear reactors, or in outer space. Another area where the material properties, most notably radiation hardness, would be valuable is in the inner tracking detectors of particle physics experiments. Here, we describe the performance of SiC diodes irradiated in the 24 GeV proton beam at CERN. Schottky measurements have been used to probe the irradiated material for changes in I–V characteristics. Other methods, borrowed from III–V research, used to study the irradiated surface include atomic force microscope scans and Raman spectroscopy. These have been used to observe the damage to the materials surface and internal lattice structure. We have also characterised the detection capabilities of bulk semi-insulating SiC for α radiation. By measuring the charge collection efficiency (CCE) for variations in bias voltage, CCE values up to 100% have been measured
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