16 research outputs found

    Effort perception and hemodynamic responses to the 3/7 vs. 3X9 methods in heart failure and in coronary artery disease patients: a randomized-cross-over study

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    Abstract Funding Acknowledgements Type of funding sources: Foundation. Main funding source(s): Fonds Erasme pour la recherche médicale Background/Introduction The hemodynamic response to strength training depends on the intensity, the time of rest between exercise sets and the duration of the exercise (1-3). A new method (the ‘3/7 method’), which consist of 5 successive sets of exercise with an increasing number of repetitions (3 to 7) separated by brief inter-set rest intervals (15 s), achieved a greater and faster strength gain after 12 weeks of training in young healthy subjects (4-5) (Fig 1). Further characterization of the tolerability of 3/7 method, as well as rise in blood pressure (BP) and heart rate (HR) it may induce, is needed in a patient population before this methodology can be applied in cardiac rehabilitation centers (6). These parameters were compared to those induced by 3 series of 9 repetitions (‘3X9 method’) with a longer inter-set rest interval (1min), using a randomized and cross-over study design. Purpose This study investigated the Borg scale and hemodynamic response of the 3/7 vs. 3X9 strength training methods in heart failure patients with reduced ejection fraction (HFrEF, Left ventricular ejection fraction (LVEF) < 40%) and patients with coronary artery disease (LVEF> 40%, CAD). Method 23 HFrEF (58±9 y, 13% female) and 22 CAD (64±10 y, 14% female) participated in the study. CAD underwent revascularization between 1 and 6 months prior to the study. Patients with decompensated heart failure, atrial fibrillation, major orthopedics disabilities were not included in the study. The strength training consisted in leg extension against a load of ~ 70% of 1 repetition maximal (1RM). Perceived exertion was also assessed at the end of the last set by using the modified Borg Scale (0-10). HR and BP were assessed noninvasively beat by beat (Task Force Monitor). We compared baseline and peak exercise values in each group. All participants signed an agreement form approved by the local Ethic Review Board. Result Baseline BP and HR and effort perception at the end of exercise did not differ between the 3/7 and 3X9 groups (Borg scale: HFrEF 3/7 method: 5,4±2,6 vs. 3X9 method: 5,8±2,5; CAD 3/7 method: 6,2±1,3 vs. 3X9 method: 6,1±1,5; p= NS) (Fig 2). HR became faster with the 3/7 method as compared to the 3X9 method in the HFrEF (85±11 vs. 83±12 bpm, p=0.014, respectively) and CAD (90±13 vs. 87±14 bpm, p=0.03, respectively) patients. In the CAD group, systolic BP increased more with the 3/7 method than with the 3X9 method (143±22 vs. 133±20 mm Hg, p<0.001). Other parameters did not differ. Conclusion The 3/7 and 3X9 strength training protocols elicit comparable effort perception and similar hemodynamic responses in HFrEF and CAD. The 3/7 method increases transiently HR by a few more beats in both groups and raises systolic BP by 10 additional mmHg in CAD patients. Taken together, this study suggests the 3/7 method is safe in patients with HFrEF and CAD, and warrants further investigation of the usefulness of the 3/7 method in cardiac rehabilitation units.info:eu-repo/semantics/publishe

    Hemodynamic Tolerance of New Resistance Training Methods in Patients With Heart Failure and Coronary Artery Disease: A RANDOMIZED CROSSOVER STUDY.

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    The purpose of this study was to determine and compare the effectiveness of three different resistance training (RT) methods for cardiac rehabilitation.info:eu-repo/semantics/publishe

    0531: Long-term experience with heart transplantation in children and patients with congenital heart disease

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    This study assessed the long-term outcome of heart (HTx) and heart-lung transplantation (HLTx) in patients with congenital heart disease (CHD) and children with non-congenital cardiac or pulmonary disease.MethodsRetrospective single-centre analysis of long-term posttransplant outcome, with chart collection of clinical and paraclinical data.ResultsFrom 1984 to 2013, 111 first-HTx, 5 HLTx and 6 re-HTx were performed (62 males), in patients aged 11.7±8.2y: 96(79%) aged <18y. Cardiopathy included 61 cardiomyopathies (50.8%), 50 CHD (41.7%), 6 retransplants (5%). HLTx included 1 Eisenmenger, 1 PPHT, and 2 pulmonary diseases. Patients with cardiomyopathy were younger than CHD (8.7y vs 14.9y).Seventeen (14%) patients had circulatory mechanical support as bridge to transplant. Acute rejection occurred more frequently within the first year post-transplant or >5th year in non-compliant teenagers. Overall 33 patients died (27%), 3.5±4.6y postTx (1 day to 16.4y, med 1.5 months), due to early multivisceral failure in 6 (18%), pulmonary hypertension in 3 (9%), acute rejection in 7 (21%), graft coronary disease in 6 (18%), sepsis in 5 (15%) and miscellaneous in 6. Graft coronary disease occurred in 15(12.4%): 4 had re-HTx, 6 died and 5 are alive. Five lymphoma occurred, 4 months to 14y after HTx, cured in 4 (1died). Patient’s survival was 85% at 1y, 81% at 5y, 70% at 10y and 61% at 20y post-transplant. Graft survival rates were respectively 82%, 68% and 52% at 5y, 10y and 20y post-transplant. Survival did not differ with pretransplant disease, age, gender, pretransplant mechanical support. Mortality was higher in patients with coronary disease (40%) than those free from (25%).Conclusionlong-term prognosis after HTx and HLTx is favourable. Graft coronary disease is the main cause of failure, less frequent than in the adult non-CHD heart-transplanted population
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