Chiral effective field theory beyond the power-counting regime

Novel techniques are presented, which identify the chiral power-counting regime (PCR), and realize the existence of an intrinsic energy scale embedded in lattice QCD results that extend outside the PCR. The nucleon mass is considered as a benchmark for illustrating this new approach. Using finite-range regularization, an optimal regularization scale can be extracted from lattice simulation results by analyzing the renormalization of the low energy coefficients. The optimal scale allows a description of lattice simulation results that extend beyond the PCR by quantifying and thus handling any scheme-dependence. Preliminary results for the nucleon magnetic moment are also examined, and a consistent optimal regularization scale is obtained. This indicates the existence of an intrinsic scale corresponding to the finite size of the source of the pion cloud.Comment: 6 pages, 4 figures, conferenc

Close encounters involving free-floating planets in star clusters

Instabilities in planetary systems can result in the ejection of planets from their host system, resulting in free-floating planets (FFPs). If this occurs in a star cluster, the FFP may remain bound to the star cluster for some time and interact with the other cluster members until it is ejected. Here, we use $N$-body simulations to characterise close star-planet and planet-planet encounters and the dynamical fate of the FFP population in star clusters containing $500-2000$ single or binary star members. We find that FFPs ejected from their planetary system at low velocities typically leave the star cluster 40% earlier than their host stars, and experience tens of close ($<1000$ AU) encounters with other stars and planets before they escape. The fraction of FFPs that experiences a close encounter depends on both the stellar density and the initial velocity distribution of the FFPs. Approximately half of the close encounters occur within the first 30 Myr, and only 10% occur after 100 Myr. The periastron velocity distribution for all encounters is well-described by a modified Maxwell-Bolzmann distribution, and the periastron distance distribution is linear over almost the entire range of distances considered, and flattens off for very close encounters due to strong gravitational focusing. Close encounters with FFPs can perturb existing planetary systems and their debris structures, and they can result in re-capture of FFPs. In addition, these FFP populations may be observed in young star clusters in imaging surveys; a comparison between observations and dynamical predictions may provide clues to the early phases of stellar and planetary dynamics in star clusters.Comment: Accepted for publication in MNRAS; 18 pages, 12 figure

Effects of deleting cannabinoid receptor-2 on mechanical and material properties of cortical and trabecular bone

Acknowledgements We thank Dr J.S. Gregory for assistance with Image J and Mr K. Mackenzie for assistance with Micro-CT analysis. Funding ABK was funded by a University of Aberdeen, Institute of Medical Sciences studentship and the Overseas Research Students Awards Scheme.Peer reviewedPublisher PD

Mechanical and material properties of cortical and trabecular bone from cannabinoid receptor-1-null (Cnr1-/-) mice

Funding ABK was funded by a studentship from the University of Aberdeen, Institute of Medical Sciences, and the Overseas Research Students Awards Scheme Acknowledgments We are grateful to Dr J.S. Gregory for assistance with Image J and Mr K. Mackenzie for assistance with Micro-CT analysis.Peer reviewedPostprin

In-vivo magnetic resonance imaging of hyperpolarized silicon particles

Silicon-based micro and nanoparticles have gained popularity in a wide range of biomedical applications due to their biocompatibility and biodegradability in-vivo, as well as a flexible surface chemistry, which allows drug loading, functionalization and targeting. Here we report direct in-vivo imaging of hyperpolarized 29Si nuclei in silicon microparticles by MRI. Natural physical properties of silicon provide surface electronic states for dynamic nuclear polarization (DNP), extremely long depolarization times, insensitivity to the in-vivo environment or particle tumbling, and surfaces favorable for functionalization. Potential applications to gastrointestinal, intravascular, and tumor perfusion imaging at sub-picomolar concentrations are presented. These results demonstrate a new background-free imaging modality applicable to a range of inexpensive, readily available, and biocompatible Si particles.Comment: Supplemental Material include

Flavor Delta(54) in SU(5) SUSY Model

We design a supersymmetric SU (5) GUT model using \Delta (54), a finite non-abelian subgroup of SU (3)f . Heavy right handed neutrinos are introduced which transform as three-dimensional repre-sentation of our chosen family group. The model successfully reproduces the mass hierarchical mass structures of the Standard Model, and the CKM mixing matrix. It then provides predictions for the light neutrino with a normal hierarchy and masses such that m{\nu},1 \approx 5\times10-3 eV, m{\nu}, 2 \approx 1\times 10-2 eV, and m{\nu},3 \approx 5 \times 10-2 eV. We also provide predictions for masses of the heavy neutrinos, and correc- tions to the tri-bimaximal matrix that fit within experimental limits, e.g. a reactor angle of -7.31o. A simple modification to our model is introduced at the end and is shown to also produce predictions that fall well within those limits.Comment: 22 page

Beef Cattle Instance Segmentation Using Fully Convolutional Neural Network

In this paper we present a novel instance segmentation algorithm that extends a fully convolutional network to learn to label objects separately without prediction of regions of interest. We trained the new algorithm on a challenging CCTV recording of beef cattle, as well as benchmark MS COCO and Pascal VOC datasets. Extensive experimentation showed that our approach outperforms the state-of-the-art solutions by up to 8% on our data

Lactobacillus ruminis strains cluster according to their mammalian gut source

peer-reviewedBackground Lactobacillus ruminis is a motile Lactobacillus that is autochthonous to the human gut, and which may also be isolated from other mammals. Detailed characterization of L. ruminis has previously been restricted to strains of human and bovine origin. We therefore sought to expand our bio-bank of strains to identify and characterise isolates of porcine and equine origin by comparative genomics. Results We isolated five strains from the faeces of horses and two strains from pigs, and compared their motility, biochemistry and genetic relatedness to six human isolates and three bovine isolates including the type strain 27780T. Multilocus sequence typing analysis based on concatenated sequence data for six individual loci separated the 16 L. ruminis strains into three clades concordant with human, bovine or porcine, and equine sources. Sequencing the genomes of four additional strains of human, bovine, equine and porcine origin revealed a high level of genome synteny, independent of the source animal. Analysis of carbohydrate utilization, stress survival and technological robustness in a combined panel of sixteen L. ruminis isolates identified strains with optimal survival characteristics suitable for future investigation as candidate probiotics. Under laboratory conditions, six human isolates of L. ruminis tested were aflagellate and non-motile, whereas all 10 strains of bovine, equine and porcine origin were motile. Interestingly the equine and porcine strains were hyper-flagellated compared to bovine isolates, and this hyper-flagellate phenotype correlated with the ability to swarm on solid medium containing up to 1.8% agar. Analysis by RNA sequencing and qRT-PCR identified genes for the biosynthesis of flagella, genes for carbohydrate metabolism and genes of unknown function that were differentially expressed in swarming cells of an equine isolate of L. ruminis. Conclusions We suggest that Lactobacillus ruminis isolates have potential to be used in the functional food industry. We have also identified a MLST scheme able to distinguish between strains of L. ruminis of different origin. Genes for non-digestible oligosaccharide metabolism were identified with a putative role in swarming behaviour.This work was supported by a Principal Investigator Award (07/IN.1/B1780) from Science Foundation Ireland to P.W. O’Toole