53 research outputs found

    An Analysis of Prosthodontic Research Productivity: Geographic, Economic, and Collaborative Perspective

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    Purpose: This study evaluated the quantity of prosthodontic literature produced globally by continent in three prosthodontic journals over a 10‐year period, 1998–2008. Prosthodontic research productivity relative to economic status of countries and collaboration among countries grouped by economic status was assessed. Materials and Methods: Three peer‐reviewed prosthodontic journals were used for the analysis of articles published in 1998, 2003, and 2008: The Journal of Prosthetic Dentistry, International Journal of Prosthodontics , and Journal of Prosthodontics . The country of every author listed for each included article was recorded. The number of articles published by each continent and each country was reported. Countries were grouped according to the World Bank economic classification system, and the number of articles published by each economic class was found. Results: The majority of publications over the 10‐year period were produced in Asia (Japan), Europe (Germany), and North America (USA). Productivity declined by 14.4% in high‐income countries while it increased in upper middle‐, lower middle‐, and low‐income countries. The majority of publications written by upper and lower middle‐ and low‐income countries were independent works. Articles resulting from collaboration increased over time for all economic classes of countries. Conclusions: The origins of prosthodontic literature are becoming more geographically and economically diverse, with increased contributions from Africa, Asia, and South America, and middle‐ and low‐income countries between 1998 and 2008. Collaboration between high‐income countries and the other economic group countries increased over time.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90374/1/j.1532-849X.2011.00776.x.pd

    Radiological research activity 1998–2007: relationship to gross domestic product, health expenditure and public expenditure on education

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    Objective The purpose of this study was to evaluate the relationship of the radiological research activity from 1998 to 2007 to the gross domestic product (GDP), health expenditure and public expenditure on education. Methods The population-adjusted research activity determined by the number of articles published, the cumulative impact factor (IF) and the cumulative IF per capita were correlated with per capita values of the GDP, health expenditure and public education expenditure. Linear regression analysis and multiple regression analysis were used for statistical analysis. Results The cumulative IF per capita correlated with the GDP per capita (R = 0.94, P  0.05). Conclusion Radiological research activity demonstrates a close relationship to the GDP, health expenditure and public expenditure on education. The last factor independently predicts research activity

    Self-medication of migraine and tension-type headache: summary of the evidence-based recommendations of the Deutsche Migräne und Kopfschmerzgesellschaft (DMKG), the Deutsche Gesellschaft für Neurologie (DGN), the Österreichische Kopfschmerzgesellschaft (ÖKSG) and the Schweizerische Kopfwehgesellschaft (SKG)

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    The current evidence-based guideline on self-medication in migraine and tension-type headache of the German, Austrian and Swiss headache societies and the German Society of Neurology is addressed to physicians engaged in primary care as well as pharmacists and patients. The guideline is especially concerned with the description of the methodology used, the selection process of the literature used and which evidence the recommendations are based upon. The following recommendations about self-medication in migraine attacks can be made: The efficacy of the fixed-dose combination of acetaminophen, acetylsalicylic acid and caffeine and the monotherapies with ibuprofen or naratriptan or acetaminophen or phenazone are scientifically proven and recommended as first-line therapy. None of the substances used in self-medication in migraine prophylaxis can be seen as effective. Concerning the self-medication in tension-type headache, the following therapies can be recommended as first-line therapy: the fixed-dose combination of acetaminophen, acetylsalicylic acid and caffeine as well as the fixed combination of acetaminophen and caffeine as well as the monotherapies with ibuprofen or acetylsalicylic acid or diclofenac. The four scientific societies hope that this guideline will help to improve the treatment of headaches which largely is initiated by the patients themselves without any consultation with their physicians

    Neoadjuvant treatment of pancreatic adenocarcinoma: a systematic review and meta-analysis of 5520 patients

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    A scoping review of comparisons between abstracts and full reports in primary biomedical research

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    Abstract Background Evidence shows that research abstracts are commonly inconsistent with their corresponding full reports, and may mislead readers. In this scoping review, which is part of our series on the state of reporting of primary biomedical research, we summarized the evidence from systematic reviews and surveys, to investigate the current state of inconsistent abstract reporting, and to evaluate factors associated with improved reporting by comparing abstracts and their full reports. Methods We searched EMBASE, Web of Science, MEDLINE, and CINAHL from January 1st 1996 to September 30th 2016 to retrieve eligible systematic reviews and surveys. Our primary outcome was the level of inconsistency between abstracts and corresponding full reports, which was expressed as a percentage (with a lower percentage indicating better reporting) or categorized rating (such as major/minor difference, high/medium/low inconsistency), as reported by the authors. We used medians and interquartile ranges to describe the level of inconsistency across studies. No quantitative syntheses were conducted. Data from the included systematic reviews or surveys was summarized qualitatively. Results Seventeen studies that addressed this topic were included. The level of inconsistency was reported to have a median of 39% (interquartile range: 14% - 54%), and to range from 4% to 78%. In some studies that separated major from minor inconsistency, the level of major inconsistency ranged from 5% to 45% (median: 19%, interquartile range: 7% - 31%), which included discrepancies in specifying the study design or sample size, designating a primary outcome measure, presenting main results, and drawing a conclusion. A longer time interval between conference abstracts and the publication of full reports was found to be the only factor which was marginally or significantly associated with increased likelihood of reporting inconsistencies. Conclusions This scoping review revealed that abstracts are frequently inconsistent with full reports, and efforts are needed to improve the consistency of abstract reporting in the primary biomedical community

    Sternal wound infections after coronary artery bypass grafting usinf bilateral skeletonized internal mammary arteries: frequency, etiology, risk factors and outcome

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    Coronary artery bypass on a beating heart (off-pump coronary artery bypass grafting or OPCABG) has become common in the last ten years in an attempt to decrease the complications associated with the use of extracorporeal circulation. There is also evidence that a new technique of OPCABG, which is performed with the use of bilateral skeletonized internal mammary arteries avoiding any procedure on the ascending aorta and a sternal closure technique based on alternative placement of figure of eight and single sternal wires, can further decrease sternal wound infections. In the retrospective part of the study, we examined the frequency, characteristics, and predisposing factors of postoperative infections, in a large cohort of patients undergoing OPCABG surgery over a period of 39 months (January 2001 - March 2004) at “Henry Dunant” Hospital, Athens, Greece. Cases were patients who developed microbiologically documented nosocomial infection. Patients who underwent valve surgery combined with coronary artery bypass surgery were excluded from the study. Twenty-one of 782 (2.7%) studied patients developed microbiologically documented nosocomial infection after OPCABG. Six of 782 studied patients (0,77%) developed sternal wound infection [4 (0.51%) developed superficial wound infection and 2 (0.26%) mediastinitis], 8 patients (1.02%) developed pneumonia, 7 (0.90%) bacteremia, 4 (0.51%) urinary tract infection (UTI), and 1 (0.13%) developed pressure sore infection. Four patients had infections at two or more different sites. Specifically, 1 patient had UTI and mediastinitis, 1 UTI and pressure sore infection, 1 pneumonia and bacteremia, and 1 pneumonia, urinary tract infection, and bacteremia. Thus, there were 26 episodes of microbiologically documented infections in 21 patients. The backward stepwise multivariable logistic regression model revealed that independent risk factors associated with development of microbiologically documented nosocomial infection were arterial hypertension, previous vascular surgery, urgent operation, postoperative atrial fibrillation, number of inotrops used during operation and after operation, transfusions of fresh frozen plasma during ICU stay and ICU stay until development of infection. ..............

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