624 research outputs found
High Resolution Observations of the Massive Protostar in IRAS18566+0408
We report 3 mm continuum, CH3CN(5-4) and 13CS(2-1) line observations with
CARMA, in conjunction with 6 and 1.3 cm continuum VLA data, and 12 and 25
micron broadband data from the Subaru Telescope toward the massive proto-star
IRAS18566+0408. The VLA data resolve the ionized jet into 4 components aligned
in the E-W direction. Radio components A, C, and D have flat cm SEDs indicative
of optically thin emission from ionized gas, and component B has a spectral
index alpha = 1.0, and a decreasing size with frequency proportional to
frequency to the -0.5 power. Emission from the CARMA 3 mm continuum, and from
the 13CS(2-1), and CH3CN(5-4) spectral lines is compact (i.e. < 6700 AU), and
peaks near the position of VLA cm source, component B. Analysis of these lines
indicates hot, and dense molecular gas, typical for HMCs. Our Subaru telescope
observations detect a single compact source, coincident with radio component B,
demonstrating that most of the energy in IRAS18566+0408 originates from a
region of size < 2400 AU. We also present UKIRT near-infrared archival data for
IRAS18566+0408 which show extended K-band emission along the jet direction. We
detect an E-W velocity shift of about 10 km/sec over the HMC in the CH3CN lines
possibly tracing the interface of the ionized jet with the surrounding core
gas. Our data demonstrate the presence of an ionized jet at the base of the
molecular outflow, and support the hypothesis that massive protostars with
O-type luminosity form with a mechanism similar to lower mass stars
Evaluation of cell culture in microfluidic chips for application in monoclonal antibody production
Microfluidic chips are useful devices for cell culture that allow cell growth under highly controlled conditions, as is required for production of therapeutic recombinant proteins. To understand the optimal conditions for growth of cells amenable of recombinant protein expression in these devices,we culturedHEK-293T cells under different microfluidic experimental conditions. The cells were cultured in polymethyl methacrylate (PMMA) and polydi-methylsiloxane (PDMS)microdevices, in the absence or presence of the cell adhesion agent poly-D-lysine. Different microchannel geometries and thicknesses, as well as the influence of the flow rate have also been tested, showing their great influence in cell adhesion and growth. Results show that the presence of poly-D-lysine improves the adhesion and viability of the cells in continuous or discontinuous flow. Moreover, the optimal adhesion of cells was observed in the corners of themicrochannels, as well as in wide channels possibly due to the decrease in the flow rate in these areas. These studies provide insight into the optimal architecture of microchannels for long-term culture of adherent cells in order to use microfluidics devices as bioreactors for monoclonal antibodies production.Fil: Peñaherrera Pazmiño, Ana Belén. Universidad Tecnológica Nacional; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Payés, Cristian. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Sierra Rodero, Marina. Universidad Tecnológica Nacional; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Vega, M.. Universidad Tecnológica Nacional; ArgentinaFil: Rosero, G.. Universidad Tecnológica Nacional; Argentina. Universidad de Buenos Aires; ArgentinaFil: Lerner, Betiana. Universidad Tecnológica Nacional; Argentina. Universidad de Buenos Aires; ArgentinaFil: Helguera, Gustavo Fernando. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Pérez, M. S.. Universidad Tecnológica Nacional; Argentina. Universidad de Buenos Aires; Argentin
Weak and Compact Radio Emission in Early High-Mass Star Forming Regions: II. The Nature of the Radio Sources
In this study we analyze 70 radio continuum sources associated with dust
clumps and considered to be candidates for the earliest stages of high-mass
star formation. The detection of these sources was reported by Rosero et al.
(2016), who found most of them to show weak (1 mJy) and
compact (0.6) radio emission. Herein, we
used the observed parameters of these sources to investigate the origin of the
radio continuum emission. We found that at least of these radio
detections are most likely ionized jets associated with high-mass protostars,
but for the most compact sources we cannot discard the scenario that they
represent pressure-confined HII regions. This result is highly relevant for
recent theoretical models based on core accretion that predict the first stages
of ionization from high-mass stars to be in the form of jets. Additionally, we
found that properties such as the radio luminosity as a function of the
bolometric luminosity of ionized jets from low and high-mass stars are
extremely well-correlated. Our data improve upon previous studies by providing
further evidence of a common origin for jets independently of luminosity.Comment: Accepted for publication in the Ap
Weak and Compact Radio Emission in Early High-Mass Star Forming Regions: I. VLA Observations
We present a high sensitivity radio continuum survey at 6 and 1.3cm using
the Karl G. Jansky Very Large Array towards a sample of 58 high-mass star
forming regions. Our sample was chosen from dust clumps within infrared dark
clouds with and without IR sources (CMC-IRs, CMCs, respectively), and hot
molecular cores (HMCs), with no previous, or relatively weak radio continuum
detection at the mJy level. Due to the improvement in the continuum
sensitivity of the VLA, this survey achieved map rms levels of 3-10
Jy beam at sub-arcsecond angular resolution. We extracted 70
centimeter continuum sources associated with 1.2mm dust clumps. Most
sources are weak, compact, and are prime candidates for high-mass protostars.
Detection rates of radio sources associated with the mm dust clumps for CMCs,
CMC-IRs and HMCs are 6, 53 and 100, respectively. This result is
consistent with increasing high-mass star formation activity from CMCs to HMCs.
The radio sources located within HMCs and CMC-IRs occur close to the dust clump
centers with a median offset from it of 12,000AU and 4,000AU,
respectively. We calculated 5 - 25GHz spectral indices using power law fits
and obtain a median value of 0.5 (i.e., flux increasing with frequency),
suggestive of thermal emission from ionized jets. In this paper we describe the
sample, observations, and detections. The analysis and discussion will be
presented in Paper II.Comment: Accepted for publication in the ApJ
Implementation of social and environmental standards: Continuity in use based on benefits and costs. A case study: the flower label program in Ecuador
135 p.In 1996 a German initiative created the Flower Label Program, with the main
intention of improving the image of the floricultural sector in this country, and
improving the social and environmental conditions in the developing countries in
which flowers are produced. The scheme to be implemented by cut flower producers
was seen by them to be an opportunity to reach a privileged position in this market,
as the continued protests led by social and environmental organizations in Germany
could create restrictions for the trade of non labelled flower in this market. Therefore
flower growers saw in the label the possibility of improving access to the German
market and gaining better prices while they accomplished what they consider to be
part of their philosophy with respect to social and environmental concerns. However,
after the label was implemented, the benefits obtained by flower growers were less
than expected, creating the possibility that companies already working with the
scheme could stop its use. This situation prompted the current study, which attempts
to determine the principal factors influencing decisions regarding continued use of
the label by flower producers.
In order to accomplish this goal, the current qualitative study uses a conceptual
framework based on the Technology Acceptance Model (TAM), in order to analyze
the influence of different factors such as perceived benefits, perceived costs, external
pressure and external variables in the final decision. Thus, the results revealed that
the most important factor influencing continuity in the label’s use is the construct
perceived costs which shows a direct influence in the final decision as well as an
indirect effect through perceived benefits. Similarly, intangible economic benefits
coming from enterprise image improvements were found to be crucial factors
determining the label’s continuity in use, as well as the construct firm’s philosophy
which influences indirectly the final decision by attenuating cost perceptions.
Additionally, the construct enterprise ideas was also found to be an important
determinant of the final decision, both directly and indirectly through the construct
enterprise image
Best Practices and Methodologies for IT Project Portfolio Management
Abstract. In today's business environment, a key factor for decision making is the IT projects portfolio management (ITPPM). IT projects must be aligned with the objectives, goals and strategies, which is achieved through the appropriate application of a methodology for ITPPM. The experienced application of a methodology depends on the experience of the managers of ITPPM, considering that the application of methodologies generates best practices, it becomes necessary to study some of the more representative methodologies and obtain the best practices that allow novice administrators to initiate their portfolio management activities in information technology projects. In this article, three methodologies are studied, from which best practices are obtained, as results; a hierarchy of best practices is obtained so that project managers can be guided or introduced in their field
Broadband VLA Spectral Line Survey of a Sample of Ionized Jet Candidates
The study of the interaction between ionized jets, molecular outflows and
their environments is critical to understanding high-mass star formation,
especially because jets and outflows are thought to be key in the transfer of
angular momentum outwards from accretion disks. We report a low-spectral
resolution VLA survey for hydrogen radio recombination lines, OH, NH, and
CHOH lines toward a sample of 58 high-mass star forming regions that
contain numerous ionized jet candidates. The observations are from a survey
designed to detect radio continuum; the novel aspect of this work is to search
for spectral lines in broadband VLA data (we provide the script developed in
this work to facilitate exploration of other datasets). We report detection of
25GHz CHOH transitions toward ten sources; five of them also show
NH emission. We found that most of the sources detected in CHOH and
NH have been classified as ionized jets or jet candidates and that the
emission lines are coincident with, or very near ( pc) these
sources, hence, these molecular lines could be used as probes of the
environment near the launching site of jets/outflows. No radio recombination
lines were detected, but we found that the RMS noise of stacked spectra
decreases following the radiometer equation. Therefore, detecting radio
recombination lines in a sample of brighter free-free continuum sources should
be possible. This work demonstrates the potential of broadband VLA continuum
observations as low-resolution spectral line scans.Comment: 38 pages, 19 figures. Accepted for publication in The Astrophysical
Journal Supplement Serie
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