Suppressing Unwanted Autobiographical Memories Reduces Their Automatic Influences: Evidence from Electrophysiology and an Implicit Autobiographical Memory Test

The present study investigated the extent to which people can suppress unwanted autobiographical memories in a mock crime memory detection context. Participants encoded sensorimotor-rich memories by enacting a lab crime (stealing a ring) and received direct suppression instructions so as to evade guilt detection in a brainwave-based concealed information test. Aftereffects of suppression on automatic memory processes were measured in an autobiographical implicit association test (aIAT). Results showed that suppression attenuated brainwave activity (P300) that is associated with crime-relevant memory retrieval, rendering innocent and guilty/suppression participants indistinguishable. However, guilty/suppression and innocent participants could nevertheless be discriminated via the late posterior negative slow wave, which may reflect the need to monitor response conflict arising between voluntary suppression and automatic recognition processes. Lastly, extending recent findings that suppression can impair implicit memory processes; we provide novel evidence that suppression reduces automatic cognitive biases that are otherwise associated with actual autobiographical memories

Countermeasure Mechanisms in a P300-Based Concealed Information Test

The detection of deception has been the focus of much research in the past 20 years. Though much controversy has surrounded one deception detection protocol, the “Control Question Test” (NRC 2003, Ben-Shakhar 2002), an alternative test, the Guilty Knowledge Test (GKT), developed by Lykken (1959, 1960), is based on scientific principles and has been well-received in the scientific community. The GKT presents subjects with various stimuli, one of which is a guilty knowledge item (termed the probe, such as the gun used to commit a crime). The other stimuli in the test consist of control items that are of the same class (termed irrelevants, such as other potentially deadly weapons: a knife, a bat, etc.) such that an innocent person would be unable to discriminate them from the guilty knowledge item. If the subject’s physiological response is greater for the guilty knowledge item, then knowledge of the crime or other event is inferred. The Guilty Knowledge Test has been adapted for use through the measurement of Event Related Potentials. Specifically, the P300 component, which is large when an individual recognizes an item as meaningful, is the primary dependent variable. We recently introduced an accurate, and countermeasure (CM)-resistant P300-based Guilty Knowledge Test (Rosenfeld et al. 2008). When subjects use CMs to all irrelevant items in the test, the probe P300 is increased rather than reduced, as in previous P300-based deception protocols, allowing detection of CM users. Evidence herein suggests this is partly due to an omit effect; the probe was the only uncountered item. 3 groups were tested: a guilty omit probe group performed an explicit response to each irrelevant item but not to the probe; an innocent omit irrelevant group saw only irrelevant items and omitted a response to one item; and a guilty no omit group had a guilty knowledge item as probe and performed an explicit response to each. We found a greater P300 amplitude to probes in the guilty omit probe condition as compared with the other two conditions, indicating a P300 enhancing effect of omitting a response to a single stimulus

Detecting Knowledge of Incidentally Acquired, Real-World Memories Using a P300-Based Concealed-Information Test

Autobiographical memory for events experienced during normal daily life has been studied at the group level, but no studies have yet examined the ability to detect recognition of incidentally acquired memories among individual subjects. We present the first such study here, which employed a concealed-information test in which subjects were shown words associated with activities they had experienced the previous day. Subjects wore a video-recording device for 4 hr on Day 1 and then returned to the laboratory on Day 2, where they were shown words relating to events recorded with the camera (probe items) and words of the same category but not relating to the subject’s activities (irrelevant items). Electroencephalograms were recorded, and presentation of probe items was associated with a large peak in the amplitude of the P300 component. We were able to discriminate perfectly between 12 knowledgeable subjects who viewed stimuli related to their activities and 12 nonknowledgeable subjects who viewed only irrelevant items. These results have strong implications for the use of memory-detection paradigms in criminal contexts

Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions.

Life and death fate decisions allow cells to avoid massive apoptotic death in response to genotoxic stress. Although the regulatory mechanisms and signalling pathways controlling DNA repair and apoptosis are well characterized, the precise molecular strategies that determine the ultimate choice of DNA repair and survival or apoptotic cell death remain incompletely understood. Here we report that a protein tyrosine phosphatase, EYA, is involved in promoting efficient DNA repair rather than apoptosis in response to genotoxic stress in mammalian embryonic kidney cells by executing a damage-signal-dependent dephosphorylation of an H2AX carboxy-terminal tyrosine phosphate (Y142). This post-translational modification determines the relative recruitment of either DNA repair or pro-apoptotic factors to the tail of serine phosphorylated histone H2AX (gamma-H2AX) and allows it to function as an active determinant of repair/survival versus apoptotic responses to DNA damage, revealing an additional phosphorylation-dependent mechanism that modulates survival/apoptotic decisions during mammalian organogenesis

Lying in the Scanner: Covert Countermeasures Disrupt Deception Detection By Functional Magnetic Resonance Imaging

Functional magnetic resonance imaging (fMRI) studies have documented differences between deceptive and honest responses. Capitalizing on this research, companies marketing fMRI-based lie detection services have been founded, generating methodological and ethical concerns in scientific and legal communities. Critically, no fMRI study has examined directly the effect of countermeasures, methods used by prevaricators to defeat deception detection procedures. An fMRI study was conducted to fill this research gap using a concealed information paradigm in which participants were trained to use countermeasures. Robust group fMRI differences between deceptive and honest responses were found without, but not with countermeasures. Furthermore, in single participants, deception detection accuracy was 100% without countermeasures, using activation in ventrolateral and medial prefrontal cortices, but fell to 33% with countermeasures. These findings show that fMRI-based deception detection measures can be vulnerable to countermeasures, calling for caution before applying these methods to real-world situations

The effects of asymmetric vs. symmetric probability of targets following probe and irrelevant stimuli in the complex trial protocol for detection of concealed information with P300

The complex trial protocol (CTP, [J.P. Rosenfeld, E. Labkovsky, M. Winograd, M.A. Lui, C. Vandenboom & E. Chedid (2008), The complex trial protocol (CTP): a new, countermeasure-resistant, accurate P300-based method for detection of concealed information. Psychophysiology, 45, 906–919.]) is a sensitive, new, countermeasure-resistant, P300-based concealed information protocol in which a first stimulus (Probe or Irrelevant) is followed after about 1.4–1.8 s by a Target or Non-Target second stimulus within one trial. It has been previously run with a potentially confounding asymmetric conditional probability of Targets following Probes vs. Irrelevants. This present study compared asymmetric vs. symmetric conditional probability groups and found no significant differences in detection rates or Probe-minus-Irrelevant P300 differences between groups. Group differences were seen in error rates and reaction times (RT) to second stimuli. These differences were, however, not diagnostic for deception vs. truth-telling, and were attributable to response perseveration

Assigned Versus Random Countermeasure-Like Responses in the P300-Based Complex Trial Protocol for Detection of Deception: Task Demand Effects

The Concealed Information Test (CIT) is a credibility assessment protocol of an entirely different nature than the traditional lie detector test. Instead of attempting to detect actual lying (the goal of the commonly used Control Question Test), the goal of the CIT is to determine whether an individual possesses knowledge of specific details of a crime or event. For example, if a murder was committed at 800 Church Avenue using a .38 caliber revolver, the CIT seeks to determine whether a suspect recognizes the address and type of weapon. The CIT presents subjects with various stimuli, one of which is a crime related item (the probe; such as the gun used to commit a murder). Other stimuli consist of control items that are of the same class (irrelevants; such as other potentially deadly weapons: a knife, a bat, etc.) such that an innocent person would be unable to discriminate them from the crime related item. If the subject’s physiological response is greater for the probe item than for irrelevant items, then knowledge of the crime or other event is inferred. The CIT can be conducted through the measurement of a variety of physiological indicators, but one highly effective method is by measuring the electrical signals at the participant\u27s scalp, termed Event Related Potentials (ERPs). One ERP component, termed the P300, is particularly large when an individual recognizes an item as meaningful, and is thus a good indicator of concealed information. We recently introduced an accurate and countermeasure resistant P300-based deception detection test called the Complex Trial Protocol (Rosenfeld et al., 2008). When subjects use countermeasures to all irrelevant items in the test, the probe P300 is increased rather than reduced (as it was in previous P300-based deception protocols), allowing detection of countermeasure users. The current experiment examines the role of task demand on the Complex Trial Protocol by forcing the subject to make countermeasure-like response to stimuli. Subjects made either a simple random button response to both probe and irrelevant stimuli (experiment 1) or a more complex, assigned, button response to probe and irrelevant stimuli (experiment 2). We found that an increase in task demand reduced the effectiveness of the test. Using random responses we found a simple guilty hit rate of 11/12 with no false positives, but only a 4/11 hit rate for countermeasure-users. Using assigned responses we found a simple guilty hit rate of 8/15 with no false positives, and a 7/16 hit rate for countermeasure-users. We herein suggest that the high level of task demand associated with these countermeasure-like responses causes reduced hit rates

A novel countermeasure against the reaction time index of countermeasure use in the P300-based complex trial protocol for detection of concealed information

A P300 deception detection protocol was tested using simultaneous versus serial countermeasures and stimulus acknowledgment responses. Previously, P300 showed recognition and elevated reaction time identified countermeasure use. Probe-irrelevant P300 differences were significant in both countermeasure groups and control group. Detection rates were 11/12 for controls, 10/12 for serial countermeasure users, and 11/13 for simultaneous countermeasure users. Reaction time detected countermeasure use in serial responders, but not simultaneous responders. The simultaneous response reaction times were indistinguishable from controls

Improved Thin, Flexible Heat Pipes

Flexible heat pipes of an improved type are fabricated as layers of different materials laminated together into vacuum- tight sheets or tapes. In comparison with prior flexible heat pipes, these flexible heat pipes are less susceptible to leakage. Other advantages of these flexible heat pipes, relative to prior flexible heat pipes, include high reliability and greater ease and lower cost of fabrication. Because these heat pipes are very thin, they are highly flexible. When coated on outside surfaces with adhesives, these flexible heat pipes can be applied, like common adhesive tapes, to the surfaces of heat sinks and objects to be cooled, even if those surfaces are curved

Financial Incentive Does Not Affect P300 in the Complex Trial Protocol (CTP) Version of the Concealed Information Test (CIT) in Malingering Detection. II. Uninstructed Subjects

Well-known research showed that the skin conductance response (SCR) of the Autonomic Nervous System (ANS) in the Concealed Information Test (CIT) is usually augmented in participants who are financially and motivationally incentivized to beat the CIT. This is not what happens with Reaction Time (RT)-based CITs, P300 CITs based on the 3-stimulus protocol, nor on the P300-based complex trial protocol for detection of malingering (however these tests differ from forensic CITs). The present report follows up the Rosenfeld et al. (1, 2) study of motivated malingerers instructed how to beat the test, with uninstructed motivated (paid and unpaid) and unmotivated (“simple malingering”) subjects, using episodic and semantic memory probes. The Test of Memory Malingering (TOMM) validated behavioral differences among groups. The “CIT effect” (probe-minus-irrelevant P300 differences) did not differ among incentive groups, although as previously, semantic memory-evoked P300s exceeded episodic memory evoked P300s. An effect of specific test-beating instructions was found to enhance the CIT effect for semantic information