Analysis of grape Vitis vinifera L. DNA in must mixtures and experimental mixed wines using microsatellite markers

DOI: 10.1021/jf011462eInternational audienc

Automatic extraction of spontaneous cries of preterm newborns in neonatal intensive care units

International audienceCry analysis has been proven to be an inescapable tool to evaluate the development of preterm infants. However, to date, only a few authors proposed to automatically extract spontaneous cry events in the real context of Neonatal Intensive Care Units. In fact, this is challenging since a wide variety of sounds can also occur (e.g., alarms, adult voice). In this communication, a new method for spontaneous cry extraction from real life recordings of long duration is presented. A strategy based on an initial segmentation between silence and sound events, followed by a classification of the resulting audio segments into two classes (cry and non-cry) is proposed. To build the classification model, 198 cry events coming from 21 newborns and 439 non-cry events, representing the richness of the clinical sound environment were annotated. Then, a set of features, including Mel-Frequency Cepstral Coefficients, was computed in order to describe each audio segment. It was obtained after Harmonic plus Noise analysis which is commonly used for speech synthesis although never applied for newborn cry analysis. Finally, six machine learning approaches have been compared. K-Nearest Neighbours approach showed an accuracy of 94.1%. To experience the precision of the retained classifier, 412 hours of recordings of 23 newborns were also automatically processed. Results show that despite a difficult clinical context an automatic extraction of cry is achievable. This supports the idea that a new generation of non-invasive monitoring of neuro-behavioral development of premature newborns could emerge. © 2021 European Signal Processing Conference, EUSIPCO. All rights reserved

Remodelage de la signalisation calcique dans la tumeur prostatique : signature moléculaire de la récidive du cancer de prostate après chirurgie ?

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Motion Estimation and Characterization in Premature Newborns Using Long Duration Video Recordings

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Voxyvi: A system for long-term audio and video acquisitions in neonatal intensive care units

International audienceBACKGROUND: In the European Union, 300,000 newborn babies are born prematurely every year. Their care is ensured in Neonatal Intensive Care Units (NICU) where vital signs are constantly monitored. In addition, other descriptors such as motion, facial and vocal activities have been shown to be essential to assess neurobehavioral development. AIM: In the scope of the European project Digi-NewB, we aimed to develop and evaluate a new audio-video device designed to non-invasively acquire multi-modal data (audio, video and thermal images), while fitting the wide variety of bedding environment in NICU. METHODS: Firstly, a multimodal system and associated software and guidelines to collect data in neonatal intensive care unit were proposed. Secondly, methods for post-evaluation of the acquisition phase were developed, including the study of clinician feedback and a qualitative analysis of the data. RESULTS: The deployment of 19 acquisition devices in six French hospitals allowed to record more than 500 newborns of different gestational and postmenstrual ages. After the acquisition phase, clinical feedback was mostly positive. In addition, quality of more than 300 recordings was inspected and showed that 77% of the data is exploitable. In depth, the percentage of sole presence of the newborn was estimated at 62% within recordings. CONCLUSIONS: This study demonstrates that audio-video acquisitions are feasible on a large scale in real life in NICU. The experience also allowed us to make a clear observation of the requirements and challenges that will have to be overcome in order to set up audio-video monitoring methods

Surgical Staff Radiation Protection During Fluoroscopy-Guided Urologic Interventions

International audienceINTRODUCTION: Over the past 20 years, the use of fluoroscopy to guide urologic surgical interventions has been constantly growing. Thus, in their daily practice, urologists and other operating room (OR) staff are exposed to X-radiation increasingly frequently. This raises questions as to the risks they encounter and the actions needed to reduce them. OBJECTIVE: Evaluate X-ray dose exposure in the members of the surgical team and determine urologist radioprotection knowledge and practices. MATERIALS AND METHODS: A prospective bicenter study was conducted within AFUF (French urology resident association) and in association with The French Nuclear Safety Authority/The Institute for Radiological Protection and Nuclear Safety (ASN/IRSN). Radiation exposure was measured on 12 operators using dosimeters (seven per operator), in staff-occupied locations in the OR using ionization chambers, and on anthropomorphic phantoms. A survey was used to gather information on radiation knowledge and safety practices of the AFUF members. RESULTS: Annual whole-body radiation doses were low (0.1-0.8 millisieverts [mSv], mostly at around 0.3 mSv), and equivalent doses were low for the fingers (0.7-15 mSv, mostly at around 2.5 mSv), and low for the lens of the eye (0.3-2.3 mSv, mostly at around 0.7 mSv). In percutaneous nephrolithotomy, extremity doses were lower when the patient was placed in dorsal decubitus compared with ventral decubitus. Pulsed fluoroscopy reduced radiation dose exposure by a factor of 3 compared with continuous fluoroscopy with no image quality loss. Radiation safety practices were poor: only 15% of urologists wore dosimeters and only 5% had been trained in the handling of X-ray generators. CONCLUSION: In the present study, radiation exposure for urologists was low, but so was knowledge of radiation safety and optimization practices. This absence of training for radiation safety and reduction, teamed with novel techniques involving long fluoroscopy-guided interventions, could result in unnecessarily high exposure for patients and OR personne

Overexpression of certain transient receptor potential and Orai channels in prostate cancer is associated with decreased risk of systemic recurrence after radical prostatectomy

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