7,090 research outputs found
Effects of omalizumab therapy on allergic rhinitis: a pilot study
The use of omalizumab, a humanized monoclonal antibody able to binding Ig-E, is currently authorized only for treatment of severe bronchial asthma. The use of omalizumab in other Ig-E related diseases is off-label, although some studies have provided promising results about it. The aim of this study was to evaluate if therapy with omalizumab in patients affected by asthma and allergic rhinitis has an impact also on allergic rhinitis-related symptoms
Electromagnetic transitions for A=3 nuclear systems
Recent advances in the study of pd radiative capture in a wide range of
center-of-mass energy below and above deuteron breakup threshold are presented
and discussed.Comment: Invited lead talk at the 19th European Conference on Few-Body
Problems in Physics, Groningen, The Netherlands, 8/23 - 8/27 2004, 5 pages, 4
figure
Chiral effective field theory predictions for muon capture on deuteron and 3He
The muon-capture reactions 2H(\mu^-,\nu_\mu)nn and 3He(\mu^-,\nu_\mu)3H are
studied with nuclear strong-interaction potentials and charge-changing weak
currents, derived in chiral effective field theory. The low-energy constants
(LEC's) c_D and c_E, present in the three-nucleon potential and (c_D)
axial-vector current, are constrained to reproduce the A=3 binding energies and
the triton Gamow-Teller matrix element. The vector weak current is related to
the isovector component of the electromagnetic current via the
conserved-vector-current constraint, and the two LEC's entering the contact
terms in the latter are constrained to reproduce the A=3 magnetic moments. The
muon capture rates on deuteron and 3He are predicted to be 399(3) sec^{-1} and
1494 (21) sec^{-1}, respectively, where the spread accounts for the cutoff
sensitivity as well as uncertainties in the LEC's and electroweak radiative
corrections. By comparing the calculated and precisely measured rates on 3He, a
value for the induced pseudoscalar form factor is obtained in good agreement
with the chiral perturbation theory prediction.Comment: 4 pages, 2 figures, revisited version accepted for publication on
Phys. Rev. Let
Electromagnetic structure of A=2 and 3 nuclei and the nuclear current operator
Different models for conserved two- and three-body electromagnetic currents
are constructed from two- and three-nucleon interactions, using either
meson-exchange mechanisms or minimal substitution in the momentum dependence of
these interactions. The connection between these two different schemes is
elucidated. A number of low-energy electronuclear observables, including (i)
radiative capture at thermal neutron energies and deuteron
photodisintegration at low energies, (ii) and radiative capture
reactions, and (iii) isoscalar and isovector magnetic form factors of H and
He, are calculated in order to make a comparative study of these models for
the current operator. The realistic Argonne two-nucleon and Urbana IX
or Tucson-Melbourne three-nucleon interactions are taken as a case study. For
=3 processes, the bound and continuum wave functions, both below and above
deuteron breakup threshold, are obtained with the correlated
hyperspherical-harmonics method. Three-body currents give small but significant
contributions to some of the polarization observables in the
H()He process and the H()H cross section at
thermal neutron energies. It is shown that the use of a current which did not
exactly satisfy current conservation with the two- and three-nucleon
interactions in the Hamiltonian was responsible for some of the discrepancies
reported in previous studies between the experimental and theoretical
polarization observables in radiative capture.Comment: 48 pages, 25 figures, 4 tables, revtex4. Submitted to Phys. Rev.
Electrodisintegration of He below and above deuteron breakup threshold
Recent advances in the study of electrodisintegration of 3He are presented
and discussed. The pair-correlated hyperspherical harmonics method is used to
calculate the initial and final state wave functions, with a realistic
Hamiltonian consisting of the Argonne v18 two-nucleon and Urbana IX
three-nucleon interactions. The model for the nuclear current and charge
operators retains one- and many-body contributions. Particular attention is
made in the construction of the two-body current operators arising from the
momentum-dependent part of the two-nucleon interaction. Three-body current
operators are also included so that the full current operator is strictly
conserved. The present model for the nuclear current operator is tested
comparing theoretical predictions and experimental data of pd radiative capture
cross section and spin observables.Comment: 5 pages, 5 figures, submitted to Eur. Phys. J.
Proton-3He elastic scattering at low energies and the "A_y Puzzle"
The Kohn variational principle and the hyperspherical harmonic technique are
applied to study p-3He elastic scattering at low energies. Preliminary results
obtained using several interaction models are reported. The calculations are
compared to a recent phase shift analysis performed at the Triangle University
Nuclear Laboratory and to the available experimental data. Using a
three-nucleon interaction derived from chiral perturbation theory at N2LO, we
have found a noticeable reduction of the discrepancy observed for the A_y
observable.Comment: 9 pages, 9 figures, to be published in the Proceedings of the 19th
International IUPAP Conference on Few-Body Problems in Physics, Bonn, 200
Weak proton capture on 3He
The astrophysical S-factor for the proton weak capture on 3He is calculated
with correlated-hyperspherical-harmonics bound and continuum wave functions
corresponding to realistic Hamiltonians consisting of the Argonne v14 or
Argonne v18 two-nucleon and Urbana-VIII or Urbana-IX three-nucleon
interactions. The nuclear weak charge and current operators have vector and
axial-vector components, that include one- and many-body terms. All possible
multipole transitions connecting any of the p 3He S- and P-wave channels to the
4He bound state are considered. The S-factor at a p 3He center-of-mass energy
of 10 keV, close to the Gamow-peak energy, is predicted to be 10.1 10^{-20} keV
b with the AV18/UIX Hamiltonian, a factor of about 4.5 larger than the value
adopted in the standard solar model. The P-wave transitions are found to be
important, contributing about 40 % of the calculated S-factor. The energy
dependence is rather weak: the AV18/UIX zero-energy S-factor is 9.64 10^{-20}
keV b, only 5 % smaller than the 10 keV result quoted above. The model
dependence is also found to be weak: the zero-energy S-factor is calculated to
be 10.2 10^{-20} keV b with the older AV14/UVIII model, only 6 % larger than
the AV18/UIX result. Our best estimate for the S-factor at 10 keV is therefore
(10.1 \pm 0.6) 10^{-20} keV b, when the theoretical uncertainty due to the
model dependence is included. This value for the calculated S-factor is not as
large as determined in fits to the Super-Kamiokande data in which the hep flux
normalization is free. However, the precise calculation of the S-factor and the
consequent absolute prediction for the hep neutrino flux will allow much
greater discrimination among proposed solar neutrino oscillation solutions.Comment: 54 pages RevTex file, 6 PostScript figures, submitted to Phys. Rev.
Hard x-ray broad band Laue lenses (80 - 600 keV): building methods and performances
We present the status of the laue project devoted to develop a technology for
building a 20 meter long focal length Laue lens for hard x-/soft gamma-ray
astronomy (80 - 600 keV). The Laue lens is composed of bent crystals of Gallium
Arsenide (GaAs, 220) and Germanium (Ge, 111), and, for the first time, the
focusing property of bent crystals has been exploited for this field of
applications. We show the preliminary results concerning the adhesive employed
to fix the crystal tiles over the lens support, the positioning accuracy
obtained and possible further improvements. The Laue lens petal that will be
completed in a few months has a pass band of 80 - 300 keV and is a fraction of
an entire Laue lens capable of focusing X-rays up to 600 keV, possibly
extendable down to 20 - 30 keV with suitable low absorption crystal materials
and focal length. The final goal is to develop a focusing optics that can
improve the sensitivity over current telescopes in this energy band by 2 orders
of magnitude
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