6,560 research outputs found

    Entanglement entropy in a holographic p-wave superconductor model

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    In a recent paper, arXiv:1309.4877, a holographic p-wave model has been proposed in an Einstein-Maxwell-complex vector field theory with a negative cosmological constant. The model exhibits rich phase structure depending on the mass and the charge of the vector field. We investigate the behavior of the entanglement entropy of dual field theory in this model. When the above two model parameters change, we observe the second order, first order and zeroth order phase transitions from the behavior of the entanglement entropy at some intermediate temperatures. These imply that the entanglement entropy can indicate not only the occurrence of the phase transition, but also the order of the phase transition. The entanglement entropy is indeed a good probe to phase transition. Furthermore, the "retrograde condensation" which is a sub-dominated phase is also reflected on the entanglement entropy.Comment: figures added; accepted by Nuclear Physics

    J/\psi polarization in photo-production up-to the next-to-leading order of QCD

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    We investigate the J/psi polarization in photoproduction at the Hadron Electron Ring Accelerator(HERA) up to the next-to-leading order of QCD. The results show that the transverse momentum p_t and energy fraction z distributions of J/psi production do not agree with the observed ones very well. The theoretical uncertainties for the z distributions of the J/psi polarization parameters with respect to various choices of the renormalization and factorization scales are too large to give an accurate prediction. The uncertainties for the p_t distributions of these parameters are small when p_t>3GeV and the obtained p_t distributions can not describe the experimental data even in this region.Comment: 5 pages, 3 figures. Discussion on the theoretical uncertainties from the choice of renormalization scale was adde

    Single cell functional proteomics for assessing immune response in cancer therapy: technology, methods, and applications

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    In the past decade, significant progresses have taken place in the field of cancer immunotherapeutics, which are being developed for most human cancers. New immunotherapeutics, such as Ipilimumab (anti-CTLA-4), have been approved for clinical treatment; cell-based immunotherapies such as adoptive cell transfer (ACT) have either passed the final stage of human studies (e.g., Sipuleucel-T) for the treatment of selected neoplastic malignancies or reached the stage of phase II/III clinical trials. Immunotherapetics has become a sophisticated field. Multimodal therapeutic regimens comprising several functional modules (up to five in the case of ACT) have been developed to provide focused therapeutic responses with improved efficacy and reduced side-effects. However, a major challenge remains: the lack of effective and clinically applicable immune assessment methods. Due to the complexity of antitumor immune responses within patients, it is difficult to provide comprehensive assessment of therapeutic efficacy and mechanism. To address this challenge, new technologies have been developed to directly profile the cellular immune functions and the functional heterogeneity. With the goal to measure the functional proteomics of single immune cells, these technologies are informative, sensitive, high-throughput, and highly multiplex. They have been used to uncover new knowledge of cellular immune functions and have been utilized for rapid, informative, and longitudinal monitoring of immune response in clinical anti-cancer treatment. In addition, new computational tools are required to integrate high-dimensional data sets generated from the comprehensive, single cell level measurements of patient’s immune responses to guide accurate and definitive diagnostic decision. These single cell immune function assessment tools will likely contribute to new understanding of therapy mechanism, pre-treatment stratification of patients, and ongoing therapeutic monitoring and assessment

    The Most Familiar Stranger: The Acculturation Of Mainland Chinese Students Studying In Taiwan

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    Mainland China and Taiwan have a homogenous macroculture, but a heterogenous microculture. To understand the acculturation of students from mainland China to Taiwan, the present study applies Berry’s(1997) two-dimensional model of acculturation, together with the concept of cultural types as its analytical framework, using focus group interviews to analyze different directions of acculturation among students from mainland China in Taiwan. The results show that regarding personal values, due to Taiwan’s restrictions on students from mainland China and the fact that they must eventually return to their place of origin, the acculturation of students from mainland China mainly takes the “separation/segregation” mode. Regarding peer selection, due to differences between individuals in their interpersonal choices, they may adopt “separation/segregation” or “integration” modes. Regarding the period of residence in Taiwan, as students from mainland China spend longer in Taiwan, they tend more towards “integration.” However, when teachers show greater contempt for the culture of mainland China, the acculturation of students from mainland China tends toward the “separation/segregation” mode

    Origin of Scaling Behavior of Protein Packing Density: A Sequential Monte Carlo Study of Compact Long Chain Polymers

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    Single domain proteins are thought to be tightly packed. The introduction of voids by mutations is often regarded as destabilizing. In this study we show that packing density for single domain proteins decreases with chain length. We find that the radius of gyration provides poor description of protein packing but the alpha contact number we introduce here characterize proteins well. We further demonstrate that protein-like scaling relationship between packing density and chain length is observed in off-lattice self-avoiding walks. A key problem in studying compact chain polymer is the attrition problem: It is difficult to generate independent samples of compact long self-avoiding walks. We develop an algorithm based on the framework of sequential Monte Carlo and succeed in generating populations of compact long chain off-lattice polymers up to length N=2,000N=2,000. Results based on analysis of these chain polymers suggest that maintaining high packing density is only characteristic of short chain proteins. We found that the scaling behavior of packing density with chain length of proteins is a generic feature of random polymers satisfying loose constraint in compactness. We conclude that proteins are not optimized by evolution to eliminate packing voids.Comment: 9 pages, 10 figures. Accepted by J. Chem. Phy

    Triangle singularity in the J/ψγpˉΔJ/\psi \to \gamma \bar{p} \Delta decay

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    In this work, we study the role of triangle singularity in the J/ψγpˉΔJ/\psi \to \gamma \bar{p} \Delta decay. We find that through a triangle mechanism, involving a triangle loop composed by ω\omega, π\pi and pp, this decay may develop a triangle singularity and produce a visible peak in the invariant mass MγΔM_{\gamma\Delta} around 1.73 GeV with a width of 0.02 GeV. Such a triangle mechanism may also cause significant spin effects on the final Δ\Delta, which can be detected by measuring its spin density matrix elements. Our calculations show that the branching ratios due to the triangle mechanism is Br(J/ψγpˉΔ,ΔπpJ/\psi\to \gamma \bar p\Delta,\Delta\to \pi p)=1.058×1061.058\times 10^{-6}. Hopefully, this reaction can be investigated at BESIII and future experiments, e.g. Super Tau-Charm Facility, and the narrow width of the induced structure, the moving TS position and the distinct features of the spin density matrix elements of the Δ\Delta may serve as signals for the triangle singularity mechanism.Comment: 7 pages, 5 figure
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