2,154 research outputs found
Synthesis of hybrid anticancer agents based on kinase and histone deacetylase inhibitors
Get PDFFragments based on the VEGFR2i Semaxanib (SU5416, (vascular endothelial growth factor receptor-2
inhibitor) and the HDACi (histone deacetylase inhibitor) SAHA (suberanilohydroxamic acid) have been
merged to form a range of low molecular weight dual action hybrids. Vindication of this approach is
provided by SAR, docking studies, in vitro cancer cell line and biochemical enzyme inhibition data as well
as in vivo Xenopus data for the lead molecule (Z)-N1-(3-((1H-pyrrol-2-yl)methylene)-2-oxoindolin-5-yl)-
N8-hydroxyoctanediamide 6
Is there an alternative explanation to post-MI emergence of mitral regurgitation; a CMR-LGE observational study
Get PDFCardiac magnetic resonance imaging in today's economic climate; a cost effectiveness analysis
Get PDFIf there is LV myocardial fibrosis should we expect to find RV myocardial fibrosis? A cardiovascular MRI study
Get PDFRetrospective review of patients with atrial fibrillation: does pulmonary vein isolation make a difference?
Get PDFCan increasing the number of excitations (NEX) in late gadolinium enhancement (LGE) imaging prove beneficial in patients who can not hold their breath for the duration of the scan time?
Get PDFThe evaluation of right and left ventricular morphology by CMR with comparison to recipient heart after heart transplant: a surgical perspective
Get PDFIs cardiovascular MRI equally effective as TEE in evaluation of left atrial appendage thrombus in patients with atrial fibrillation undergoing pulmonary vein isolation
Get PDFMitral regurgitation recovery and atrial reverse remodeling following pulmonary vein isolation procedure in patients with atrial fibrillation: a proof of concept cardiac MRI study
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