The violent frontline: space, ethnicity and confronting the state in Edwardian Spitalfields and 1980s Brixton

This article discusses in comparative terms the relationship between space, ethnic identity, subaltern status and anti-state violence in twentieth century London. It does so by comparing two examples in which the control of the state, as represented by the Metropolitan Police, was challenged by minority groups through physical force. It will examine the Spitalfields riots of 1906, which began as strike action by predominantly Jewish bakers and escalated into a general confrontation between the local population and the police, and the Brixton riots of 1981, a response to endemic police harassment of mainly Caribbean youth and long-term economic discrimination in that area of South London. It will begin by dissecting the association of physical metropolitan space with the diasporic ‘other’ in the Edwardian East End and post-consensus South London, and how this ‘othering’ was influenced both by the state and the anti-migrant far right. It will then interrogate the difficult relationship between the Metropolitan Police and Jewish and Caribbean working class communities, and how this deteriorating relationship exploded into in extreme violence in 1906 and 1981. The article will conclude by assessing how the relationships between space, identity and violence influenced long-term national and communal narratives of Jewish and Caribbean interactions with the British state

Host-Pathogen Interaction during Pneumococcal Infection in Patients with Chronic Obstructive Pulmonary Disease

Acute exacerbation is a frequent complication of chronic obstructive pulmonary disease (COPD). Recent studies suggested a role for bacteria such as Streptococcus pneumoniae in the development of acute exacerbation. For this study, we investigated the following in COPD patients: (i) the epidemiology of pneumococcal colonization and infection, (ii) the effect of pneumococcal colonization on the development of exacerbation, and (iii) the immunological response against S. pneumoniae. We cultured sputa of 269 COPD patients during a stable state and during exacerbation of COPD and characterized 115 pneumococcal isolates by use of serotyping. Moreover, we studied serum immunoglobulin G (IgG) antibody titers, antibody avidities, and functional antibody titers against the seven conjugate vaccine serotypes in these patients. Colonization with only pneumococci (monocultures) increased the risk of exacerbation, with a hazard ratio of 2.93 (95% confidence interval, 1.41 to 6.07). The most prevalent pneumococcal serotypes found were serotypes 19F, 3, 14, 9L/N/V, 23A/B, and 11. We calculated the theoretical coverage for the 7- and 11-valent pneumococcal vaccines to be 60 and 73%, respectively. All patients had detectable IgG levels against the seven conjugate vaccine serotypes. These antibody titers were significantly lower than those in vaccinated healthy adults. Finally, on average, a 2.5-fold rise in serotype-specific and functional antibodies in S. pneumoniae-positive sputum cultures was observed during exacerbation. Our data indicate that pneumococcal colonization in COPD patients is frequently caused by vaccine serotype strains. Moreover, pneumococcal colonization is a risk factor for exacerbation of COPD. Finally, our findings demonstrate that COPD patients are able to mount a significant immune response to pneumococcal infection. COPD patients may therefore benefit from pneumococcal vaccination

‘This is Staffordshire not Alabama’: Racial Geographies of Commonwealth Immigration in Early 1960s Britain

In the 1964 general election, the English town of Smethwick outside Birmingham became infamous for the unprecedented way in which issues of immigration, race and racism entered British national politics. Conservative candidate Peter Griffiths captured the Smethwick seat in Parliament from long-standing Labour MP Patrick Gordon Walker, aided by the slogan ‘If you want a nigger neighbour, vote Liberal or Labour’—a watershed episode soon overshadowed by the rise of Powellism in the late 1960s. Debates between Griffiths, his supporters and his opponents in the early to mid-1960s about the local and national implications of ‘coloured’ immigration (particularly of Indian Sikhs) from the Commonwealth and the legacy of empire drew upon a densely entangled set of global reference points that went beyond a ‘multi-racial’ Britain being reshaped by its ‘multi-racial’, postcolonial Commonwealth. Racist rhetoric, as well as an increasingly assertive anti-racist activism by the Indian Workers' Association and other groups, turned to analogies ranging from Nazi Germany to apartheid South Africa and racial segregation in the United States, as well as to protest techniques inspired by Gandhi in colonial India and African Americans in the civil rights movement. In Smethwick c. 1964, the global met the local, illuminating transnational flows of people and ideas about race and cultural diversity nonetheless contingent upon their time and place