56 research outputs found
Research of Magnetic Field Distribution in the Working Area of Disk Separator, Taking Into Account an Influence of Materials of Permanent Magnets
Based on the results of a numerical-field analysis of the distribution of the magnetic force field in the working area of the disk magnetic separator, designed to clean bulk substances from ferromagnetic inclusions, the influence of the magnetic material of the poles of the magnetic system on the field distribution is determined. A consistent study of two magnetic systems assembled on the basis of magnetic materials of different classes is carried out. The finite element method implemented in the COMSOL Multiphysics software environment is used to calculate the distribution of magnetic induction in a disk magnetic separator with rare-earth and ferrite magnets. Due to the complexity of the spatial geometry of the force field in the working area of the disk magnetic separator, a three-dimensional model of the magnetic system is developed. A comparative analysis of the distribution of the magnetic force field in the working area of the disk separator with a highly coercive magnetic system and with a magnetic system based on ferrite blocks is carried out. As a result of the analysis, it is found that the indicators of the intensity and heterogeneity of the magnetic field for a highly coercive magnetic system significantly exceed the corresponding parameters of a ferrite magnetic system. It is proved that when choosing magnets for the magnetic system of a disk separator, preference should be given to highly coercive alloys, the magnetic properties of which significantly exceed the magnetic properties of ferrite magnets. To reduce the cost of the magnetic system of the disk separator, the use of a combined magnetic system assembled from magnetic materials of different classes is proposed. Studies of combined magnetic systems with various mass fractions of magnetic materials are done. The ratio of the mass fractions of magnets of various properties in the poles of the magnetic system is determined, at which sufficiently high magnetic characteristics are provided in the working area. It is shown that the presence of a ferrite fraction in the magnetic poles not only reduces the cost of the magnetic system of the separator, but also reduces the mass of the system. The tasks of further research are justifie
DETERMINATION OF THE RATIONAL GEOMETRICAL PARAMETERS OF PLATE TYPE ELEMENTS OF MAGNETIC MATRIX OF THE POLYGRADIENT SEPARATOR
Introduction. Polygradient magnetic separation has wide application in industry and in biomedicine. Working process in polygradient separators takes place in a matrix, magnetic elements of which create magnetic forces sufficient to remove small ferro- and paramagnetic inclusions. Problem. The influence of mutual arrangement of elements on character of distribution of magnetic field is not taken into account during calculation of characteristics of magnetic field in magnetic matrixes. It makes comparative analysis of matrixes of different configurations quite difficult. Fulfillment of comparative analysis of strength characteristics of magnetic fields of multicomponent matrixes of polygradient separators of various configurations requires further researches. Goal. To determine the dependence of the strength characteristics of the polygradient electromagnetic separator on the geometrical parameters of the plate type elements of the multicomponent matrix. Methodology. The finite element method for calculation of power characteristics of separator magnetic field, method of comparative analysis and simple search method for determination of rational geometric parameters of the matrix have been used during the solution of the paper problem. Results. Estimation of entire spectrum of force field in plane of working zones of investigated structures in two-dimensional location for determination of rational variants of polygradient matrixes has been done. The main stages of computational experiment are given. Method of comparative analysis of power characteristics of investigated variants of matrix structures with corresponding characteristics of basic version of separator for determination of rational geometrical variants of polygradient matrixes has been applied. By results of calculations the rational geometric parameters of polygradient matrix has been chosen. The characteristics of power magnetic fields in working gaps of matrixes of polygradient separator have been studied. It made possible to determine the rational structural variants of matrix on basis of parameter of effective area of working zone. Practical value. The results of research can be used in practice of design of electromagnetic separators with polygradient matrixes
Characteristics of plasma lipid profile in patients with hypertension, comorbid with gouty arthritis, and its correction with atorvastatin
Подагра, коморбідна з артеріальною гіпертензією, супроводжується комплексом метаболічних змін, серед яких однією з найбільш виражених є дисліпідемія. У роботі 22 пацієнти з артеріальною гіпертензією та супровідною подагрою додатково до планової терапії приймали аторвастатин дозою 20 мг на добу протягом 42 діб. Було виявлено, що у даної групи хворих найбільш виражена підвищена фракція холестерину ліпопротеїдів низької щільності (91 % хворих). На фоні лікування відбулося достовірне зниження загального холестерину на 24,96 %, холестерину ліпопротеїдів низької щільності на 27,21 %, холестерину ліпопротеїдів дуже низької щільності на 21,82 %, тригліцеридів на 24,69 %. Холестерин ліпопротеїдів високої щільності та індекс атерогенності показали недостовірну тенденцію до зниження.Arterial hypertension is one of the most common risk factors for cardiovascular disease often accompanied by chronic forms of gout. This disease combination is associated with the development of hyperlipidemia, which increases cardiovascular risk even more. No current studies have been performed to check the effect of medium doses of atorvastatin in such comorbid pathology. 22 male patients with gout and arterial hypertension had lipid profile checked before and after 42 days of standard treatment additionally including 20 mg of atorvastatin daily. It was found that initial LDL cholesterol was elevated in 91% of studied subjects. After the treatment significant lowering of total cholesterol by 24.96%, LDL cholesterol by 27.21%, VLDL cholesterol by 21.82%, triglyceride levels by 24.69% was discovered. HDL cholesterol and atherogenic index showed insignificant decrease
Endothelial dysfunction: diagnostic value, methods of determining
Представленная работа посвящена исследованиям по эндотелиальной дисфункции, механизмам её формирования, наиболее часто используемым методам её определения, результатам по их информативности при различной патологии. Собственный анализ чувствительности и специфичности представленных методов позволил сделать вывод, что совместное определение эндотелий-зависимой и независимой реактивности сосудов и подсчёта ЦЭ является наиболее чувствительным (88%) и специфичным (100%) способом оценки ДЭ.Background: endothelial dysfunction is considered to be a disruption in any of endothelial functions, leading to endothelial activation and subsequent development of atherosclerosis. Taking into account growing importance of early cardiac disease diagnostics endothelial dysfunction can be used as a marker of developing atherosclerosis. The most frequent methods are ultrasound brachial artery dilatation assessment, circulating endotheliocytes count, endothelin-1, fWF and TNF-α concentration measurement, proinflamatory (IL-1, IL-2, IL-5, IL-7, IL-12) and antiinflammatory (IL-4, IL-10) interleukins concentration measurement.
Methods and results: Data of 10 healthy adult volunteers and 37 patients with cardiac pathology was analyzed. Sensivity and specificity of endothelium-dependent and –independent vasodilatation and circulating endothelial cells count was determined according to standard procedure.
Conclusion: Analysis of the sensitivity and specificity of the presented methods led to the conclusion that the joint determination of endothelium-dependent and independent vasodilatation and counting circulating endothelial cells is the most sensitive (88%) and specific (100%) method of assessing presence of endothelial dysfunction
Generation of electromagnetic fields of extremely high intensity by coherent summation of Cherenkov superradiance pulses
We demonstrate both theoretically and experimentally the possibility of correlating the phase of a Cherenkov superradiance (SR) pulse to the sharp edge of a current pulse, when spontaneous emission of the electron bunch edge serves as the seed for SR processes. By division of the driving voltage pulse across several parallel channels equipped with independent cathodes we can synchronize several SR sources to arrange a two-dimensional array. In the experiments carried out, coherent summation of radiation from four independent 8-mm wavelength band SR generators with peak power 600 MW results in the interference maximum of the directional diagram with an intensity that is equivalent to radiation from a single source with a power of 10 GW
Coherent summation of emission from relativistic Cherenkov sources as a way of production of extremely high-intensity microwave pulses
For relativistic Cherenkov devices, we investigate the process of high-power microwave pulse generation with its phase correlating to the sharp edge of an e-beam current pulse. Our theoretical consideration is referred to quasi-stationary and superradiative (SR) generation regimes when spontaneous emission of the e-beam edge serves as the seed for the development of further coherent oscillations. Phase correlation of the excited microwave pulses with the characteristics of the current pulse front and/or an initial external electromagnetic pulse has been additionally confirmed by particle-in-cell simulations. Pulse-to-pulse stability of the radiation phase within several percents of the oscillation period makes it possible to arrange multichannel schemes producing mutually coherent microwave pulses. In the experiments that have been carried out, the cathodes of independent generators were powered by identical accelerating pulses from strictly synchronized voltage modulators, or by splitting the pulse from a single powerful modulator. For the 2-ns regime with the power of each Ka-band backward-wave oscillator about 100 MW, we demonstrate quadratic growth of the power density in the interference maximum of the directional diagram. In a short pulse SR regime, with the peak power of 600 MW in a single channel, for a four-channel 2-D array, we attained a 16-fold radiation intensity gain
Iron-based ultrafine particles made in mode solutions and industrial waste waters
Iron and attendant impurities settled from industrial waste water by ferritizing and formation of nanoparticles in batch bacterials culture have been studies. Iron settlement by ferritizing forms magnetic sediment extractable by magnetic separation..
LACTOFERIN IN THE PROBLEM OF ANTI-INFECTIOUS PROTECTION OF BABIES IN THEIR FIRST YEAR OF LIVING
The author summarizes the results of research of the antibacterial, antiviral and antifungal properties of multifunctional human protein — lactoferrin, in order to determine the prospects for its use in the prevention and treatment of infectious diseases of children in their first year of life. The mechanisms of anti-infectious effect of this protein with breastfed children have been described. Basic differences between human lactoferrin and cattle lactoferrin have been shown. Biotechnology of obtaining recombinant human lactoferrin from the milk of genetically engineered dairy animals (goat-producers) has been described. According to the studies, both by physical and chemical parameters and biological activity, human lactoferrin, obtained from milk-producing goats, corresponds to its natural counterpart
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