Correlation of Left Atrial Volume Index With Pro-BNP in Heart Failure With Preserved Ejection Fraction

Objective: To determine the correlation between left atrial volume index and Pro-BNP in heart failure patients with preserved ejection fraction. Study Design: Descriptive Cross-Sectional Study. Setting: This study was conducted at the Department of Cardiology, Liaquat University of Medical & Health Sciences (LUMHS), Jamshoro, Pakistan. Duration: Six months after the approval of the synopsis, from March 26, 2021, to September 25, 2021. Materials and Methods: All patients who fulfilled the inclusion criteria and visited LUMHS, Jamshoro were included in the study. Informed consent was taken after explaining the procedure, risks, and benefits of the study. Peripheral venous blood samples were obtained for the assessment of Pro-BNP levels. A detailed comprehensive echocardiography was performed on all patients. All collected data were entered into the proforma attached at the end and used electronically for research purposes. Results: The age of the patients ranged from 19 to 59 years, with a median of 58 and an interquartile range of 12. In the distribution of gender, 20 (60.5%) patients were male while 13 (39.4%) were female. Pearson’s correlation coefficient showed a weak and non-significant linear correlation between left atrial volume index and Pro-BNP levels (r = 0.134, P > 0.05). Conclusion: It is concluded that a weak correlation was noted between left atrial volume index and Pro-BNP levels. More studies are necessary to evaluate the statistical association with a larger sample size and with more parameters in multiple study centers in Pakistan to validate the findings of the present study